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Biomedical subjects

H Brunner

Publications and source records attributed to H Brunner.

At least 91 records · Page 5Linked to original sources
PubMed1985

[Nutrition in the first week of life--comparative studies between 2 different nutrition regimens].

The research work to optimize nutrition in the first week after birth was carried out with two groups of healthy newborns. The food quantity of the first group was calculated according to the formula (days of life--1) X 70 ml, that of the second group according to the formula [days of life X 10) + 20] X 5 ml. With the nutrition according to formula 2 combined with the so - called early - feeding a rapid increase was reached in the drinking quantity. Potential nutrition deficiency troubles had to be avoided by this way. The statistical analysis according to the body weights which revealed daily didn't proof any statistical differences. A food calculation according to formulas must be judged to be obsoletely. The nutrition during the first weeks of life ought to be effected by nursing or balanced nutrition based on formula both with regard to frequency and quantity on demand a rooming in system.

Body Weight↗
PubMed1985

Use of counter-immunoelectrophoresis for the detection of chlamydial antigens in serum.

An increasing number of reports on Chlamydia trachomatis pneumonia in infancy has recently been published in the literature. Demonstration of the aetiologic agent depends, however, on laborious culture procedures and serological techniques. Based on the observation of a cross-reaction between certain Acinetobacter species and Chlamydiae, the detection of chlamydial antigens in sera of 13 infants with pneumonia due to Chlamydia trachomatis was performed with antiserum to Acinetobacter by the counter-immunoelectrophoresis technique.

Acinetobacter↗
PubMed1979

[The treatment of acute pancreatitis in Austria: results of a questionnaire].

The treatment of acute pancreatitis as currently practised in Austria was evaluated by means of a questionnaire mailed to all medical and surgical departments in Austrian hospitals. Fasting, analgesics and parenteral fluid therapy are applied routinely and proteinase inhibitors are used in nearly all hospitals. The efficacy of placing the pancreas at rest by withdrawal of oral fluids, nasogastric suction or antacids is variably assessed. Pharmacological inhibition of pancreatic secretion is achieved mainly by anticholinergics, whilst less often glucagon is prescribed. Antibiotic prophylaxis is widely applied. The main indications for surgery are complications and pre-existing biliary tract disease. These results are compared with the literature.

Acute Disease↗
PubMed1979

[Significance of Ureaplasma urealyticum in the sperm of fertility patients].

U. urealyticum was found in the semen of 12.9% of the patients, who attended a fertility clinic. Ureaplasma counts of more than 1,000 CFU/ml were demonstrated in 8.6% of cases. Non-specific genital infection caused by U. urealyticum was rarely diagnosed, and there was no correlation of the ureaplasma counts and the spermatological findings in cases without inflammation.

Humans↗
PubMed1979

Electron microscopic studies on the attachment of Mycoplasma pneumoniae to guinea pig erythrocytes.

A mechanism of pathogenicity of Mycoplasma pneumoniae is its ability to attach to the surface of mammalian cells. It has previously been demonstrated by others that M. pneumoniae adheres with a specialized terminal structure, the "tip," to ciliated epithelial cells of the respiratory tract. In this report we show by electron microscopy that M. pneumoniae adsorbs with membrane sites other than the tip to guinea pig erythrocytes.

Animals↗
PubMed1979

Complement components (C1, C2, C3, C4) in bronchial secretions after intranasal infection of guinea pigs with Mycoplasma pneumoniae: dissociation of unspecific and specific defense mechanisms.

Shortly after intranasal infection of guinea pigs with Mycoplasma pneumoniae, the titers of the complement components increased significantly in bronchial secretions by the folllowing amounts, compared with the titer of a control group: C1, about 2-fold; C2, 1.6-fold; C3, 17-fold; and C4, 942-fold. Histopathological signs of inflammation were not apparent at this time. At 2 weeks after infection, when the titers of complement components in the bronchial secretions were at the level of control values or lower, the serum antibody titer increased, and it reached the highest level at 6 weeks after infection. Therefore, one can distinguish two phases of reaction of the macroorganism to intranasal inoculation. The increase in complement components shortly after infection may represent an earlyunspecific defense mechanism of the host before the specific immune response becomes effective, since the complement system can be activated by M. pneumoniae via the classical as well as the alternative pathway in the absence of antibodies.

Administration, Intranasal↗
PubMed1979

Serological cross-reactions between Acinetobacter calcoaceticus and chlamydiae.

A cross-reaction between Acinetobacter calcoaceticus and chlamydiae is described. A water-soluble, heat stable, non-dialyzable antigen was extracted from Acinetobacter species by boiling. This antigen fixed complement in the presence of homologous hyperimmune sera from rabbits or guinea pigs and in the presence of heterologous human or hyperimmunized animal sera containing chlamydial antibodies. Hyperimmune antisera to the extracted antigen, or to suspensions of live acinetobacters, also reacted in complement fixation with a group-specific antigen.

Acinetobacter↗
PubMed1979

[Complement-fixing antibodies to chlamydia in the population (author's transl)].

2,213 sera of normal persons and of men with nongonococcal urethritis were tested by CF. 4.5% of the males, 9.2% of the females, and 10.8% of the urethritis-patients had titers of 1 : greater than or equal to 16 when tested against a group-specific chlamydial antigen. The usefullness of the CFT for seroepidemiological studies was confirmed.

Adolescent↗
PubMed1979

[The mycoplasma-pneumonia. A model for the study of the pathogenesis of infectious diseases (author's transl)].

The known mechanisms of pathogenicity of Mycoplasma pneumoniae are discussed. In addition, evidence is provided for the participation of the immune system in the pathogenesis of M. pneumoniae disease. In a working hypothesis the stimulation of a protective and/or a reactive immune response is postulated, depending on the predisposition of the host, the infecting dose, the frequency of contact and the virulence of the organisms. Because well studied animal models are available, the Mycoplasma-Pneumonia is well suited to investigate the pathogenesis of infections caused by bacteria and the defense of the host.

Animals↗
PubMed1978

[Somatostatin in the treatment of acute haemorrhage from a duodenal ulcer (author's transl)].

A massive haemorrhage from a duodenal ulcer verified on endoscopy in a 21 year-old patient was stopped by a 62--hour infusion of somatostatin at a dosage of 250 microgram/hour. Suppression of gastric secretion is probably more important than the reduction in splanchnic blood flow with regard to the mechanism of action of this drug. No side effects were observed.

Adolescent↗
PubMed1978

Determination of IgG, IgM, and IgA antibodies to Mycoplasma pneumoniae by an indirect staphylococcal radioimmunoassy.

An indirect staphylococcal radioimmunoassay (SRIA) has been developed for determination of M. pneumoniae antibodies. This test allows the detection of antibodies in various immunoglobulin (Ig) classes similar to the previously described radioimmunoprecipitation test (RIP). SRIA has two advantages over RIP: first, it uses 100-fold less anti-Ig reagents than RIP; second, bound can be separated from unbound antigen more easily by the relatively heavy staphylococci. SRIA antibodies, belonging to the IgA class of Ig, could be detected in nasal secretions of volunteers infected intranasally with ts H43 of M. pneumoniae. In sera of patients with M. pneumoniae pneumonia antibodies to the IgG or the IgM class of Igs could be determined separately. This is especially important for an early diagnosis of M. pneumoniae disease.

Antibodies, Bacterial↗