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Biomedical subjects

H Denck

Publications and source records attributed to H Denck.

At least 73 records · Page 4Linked to original sources
PubMed1979

[Initial experiences with a nation-wide Austrian study of adjuvant chemo- and immunotherapy of colorectal cancer following radical surgery].

The outline of a cooperative study for adjuvant Chemo-Immunotherapy on radically operated Colon-Rectum-Carcinoma, is presented. One group of patients receiving Placebo, has to be randomized against another group who postoperatively received Chemo-Immunotherapy consisting of 5-Fluorouracil and CCNU and Corynebacterium parvum, which was administered intermittently, throughout one year. Patients with Rectum-Carcinoma additionally receive radio-therapy with 1500 rad HD before surgery and 4500--5000 rad HD postoperatively with Cobalt-60. The central documentation, and randomization, is provided at the Institute for Cancer Research of the University of Vienna.

Antineoplastic Agents↗
PubMed1979

Radiological procedures in portal hypertension.

Radiological diagnosis in portal hypertension is of paramount importance for proper treatment. The site of portal obstruction is determined preoperatively by either direct (splenoportography, transumbilical portography, epiploography, selective percutaneous transhepatic catheterization) or direct (catheterization of the celiac truncus and/or the superior mesenteric artery) methods. After a shunt procedure the examination can best be done with a balloon catheter, by direct catheterization of a shunt or by indirect splenoportography. Recently, the radiologist has started to do the treatment by percutaneous transhepatic injection of a sclerosing agent into the gastric coronary vein. For each different method the advantages and disadvantages, the indications and technical procedure are described and discussed.

Adolescent↗
PubMed1979

[Successes, failures and complications in thrombolytic therapy in peripheral, arterial and venous occlusions].

Thrombocytic therapy in peripheral arterial and venous vessel occlusion represents a clearly described alternative towards the surgery of vessels. A success rate of 36.5% can be found in subacute peripheral arterial thrombosis and 46.3% in subacute thrombotic occlusion of a bypass-graft. Contrary to that, a rate of 29.8% can be found in complications or side-effects respectively. In cases of peripheral deep venous thrombosis, a partial or full success can be found in 72%. However, the rate of complication amounting to 44.2% is comparatively high. The longer thrombolytic therapy with streptokinase or urokinase will last, the more frequently and more serious will be the complications, such as bleedings of different kind as well as increase of temperature to mention the most frequent ones. The application of urokinase is absolutely possible today, however, the use of urokinase seems to be only justified, if a thrombolytic therapy with streptokinase was carried out successfully and a subsequent surgical therapy was not possible. The present costs of this preparation are far too high for urokinase to be applied routinely. A thrombolytic therapy with SK as well as with UK has to be followed by an anticoagulant treatment.

Arterial Occlusive Diseases↗
PubMed1978

[Prognosis of cardia carcinoma].

Based on a material of 223 patients treated for cardia carcinoma the surgical problems and the results after palliative, radical and enlarged resection are discussed. In the early stage without nodular involvement (I) in 72% of the radically operated patients a 5-years and 10-years cure could be obtained, in relation to all patients observed the success, however, is only 10% for 5-years and 8% for 10-years cure. This is caused by the fact that stage I was found in only 10% of the patients admitted to our hospital. The need for a close observation programm for clearly defined high risk groups must be pointed out and the possibilities of a special postoperative adjunct therapy should be fully used.

Adult↗
PubMed1978

[Endoscopic sclerosing of oesphageal varices (author's transl)].

Due to unsatisfactory results of porto-systematic shunts in oesophageal varices as prophylaxis or as therapy in haemorrhagic states local therapeutic measures have attracted attention, especially sclerosing the wall of the oesophagus by an endoscopic technique.

Esophageal and Gastric Varices↗
PubMed1977

[Operative therapy: thrombectomy, umbrella filter, caval ligation (author's transl)].

The goals of our therapeutic trials in acute leg and pelvic vein thrombosis are to 1. Prevent embolism, 2. Salvage the limb, 3. Prevent the postthrombotic syndrome. Early surgical thrombectomy guarantees salvage of the limb in most cases; the frequency of pulmonary embolism can be significantly reduced compared to the spontaneous course and frequency of the postthrombotic syndrome. For recidivistic pulmonary embolism the umbrella filter of Mobin-Uddin, which is implanted via a transjugular pathway, is today the treatment of choice. Further embolisms are rare. For massive lung embolism, extracorporal circulation is necessary: The formerly used Trendelenburg operation is no longer justified.

Acute Disease↗
PubMed1977

[Surgery of the extracranial cerebral vessels. (Indication and results)].

Surgery of the extracranial cerebral vessels nowadays under right indication and operative technique is one of the most satisfying areas of vascular surgery. Our present status of indication is shown in table 1; it should be pointed out that the classical indication is a lesion of the internal carotid artery with a Transitoric Ischemic Attack, but also in cases of progressive stroke with acute carotid occlusion the operation will be successful relentless of any time limit as long as the patient is conscious. For the extrathoracal bypass procedure we now prefer the subclavio-subclavian bypass to the formerly performed carotio-subclavian bypass.

Carotid Artery Diseases↗