[Strategy in central subclavian occlusion].
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Biomedical subjects
Publications and source records attributed to H Denck.
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As long-term results of portosystemic shunt operations for decompression of the portal hypertension are unsatisfactory, the author's therapeutic trials are directed increasingly at local treatment of varicosity. One treatment used is esophagoscopic submucosal sclerosing therapy of the esophageal wall for detachment of the varices from the surface. This method proved to be of great value in 420 patients, as the incidence of fatal recurrences of bleeding was only 12% and primary mortality was 15%. Suggested indications for endoscopic mural sclerosing are discussed. Mural sclerosing associated with transhepatic percutaneous esophageal varix sclerosis (following Lunderquist) might improve the results further in some cases.
The great number of people with varicosities and the relatively high percentage of venous pathology among this group shows the importance of their detection and treatment. The results achieved in more than 1000 operations on varicose legs underline the great benefits arising from surgical treatment of the varicose saphenous vein. The treatment of chronic venous insufficiency in the malleolar region has been aided by the use of the Klapp tenotoma. The simple and atraumatic manipulation of this instrument enables the surgeon to overcome the most important obstacles in this region, the perforator veins (Cockett I, II), the venous leg ulcer and the corona phlebectatica paraplantaris. Conscientious postoperative supervision of the patient by the surgeon personally or by a dermatologist trained in this speciality is an essential condition for the successful operative treatment of varicose veins.
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A lumbar sympathectomy was performed on 36 patients with angiographical verified arterial occlusion on the upper and lower leg. Pre- and postoperative partly the lower leg flow was registered by air plethysmography and the lower leg and bridge of foot flow simultaneously registered by the Straine gauge plethysmography. Independent of the method an increase of the arterial blood flow was noticed with 40% of the patients. In spite of this improvement the registered values after the reactive hyperemia in lower leg and bridge of foot are still clearly restricted. The remaining 60% of the patients however showed a clear worthening of the blood flow conditions.
The surgery of solitary metastasis of the lung has special ranges of indication which refer to pathomorphology, cardiorespiratory and oncological programming. By systematical selection the own material of 45 cases shows a two year survival time of 33% and a five year of 11%. Last results with survival rate are similar to the treatment of the bronchus carcinoma of all stages and are further justifying this therapeutical consequence.
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Indications for thrombectomy in acute thrombosis of the deep veins of the pelvis and lower extremities are: 1. Phlegmasia coerulea dolens with imminent danger of venous gangrene. 2. All cases: a) with contraindications for a therapy with fibrinolysis, b) after therapy-failures with thrombolytic therapy, c) thrombosis of more than 3 days duration. 3. In cases associated with tumours or trauma. If a thrombectomy can only be partially achieved, or in cases with an old thrombosis, a temporary arteriovenous fistula is performed. In cases with phlegmasia alba and the inexistence of danger for an extremity treatment with fibrinolysis, this is preferable in the first three days after onset, if general conditions permit this treatment. Results of venous thrombectomies are particularly astonishingly good in phlegmasia coerulea and it is therefore mandatory to transfer all fresh cases of thrombosis of the deep veins of the peelvis and lower extremities to an angiologic center in order to differentiate cases for fibrinolytic therapy, from those which require surgical intervention.
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A preliminary evaluation of a randomized, prospective clinical study of combined polychemotherapy in bronchial carcinoma is presented. The comparison of survival-curves shows a positive tendency in favor of the treatment and justifies the continuation and extension of the study. The data presented are based on the findings of 106 patients who underwent radical surgical operations due to bronchial carcinoma and of 114 patients as a comparison who in addition received aftertreatment with high doses of cytostatics applied intermittently. The importance of the influence of the clinical symptoms on the prognosis and on the effect of the Chemotherapy is emphasized.
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The treatment of acute arterial occulsion, especially emboli and also thromboses associated with a complete ischaemia is the domain of the surgeon. Subacute or chronic arterial occlusion -- uni- or myltilocular --are suited for a trial of thrombolytic therapy, with an approximate success rate of 40%. When thrombolysis is contraindicated, then transluminal dilatation according to Dotter can be attempted in cases of short stenosis. A new and successful indication for thrombolysis is in the therapy of cases of late reocclusion after vascular reconstructive operations. The preliminary results in this field are very good, especially in the aortoiliac region. The indications, the practical details, the results and complications of thrombolytic therapy with streptokinase are discussed.
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