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H Fukumi

Publications and source records attributed to H Fukumi.

54 records · Page 3Linked to original sources
PubMed1969

Summary report on Hong Kong influenza in Japan.

In the 2 months following the onset of the influenza epidemic in Hong Kong in July 1968, there must have been many importations of the virus into Japan both from Hong Kong and from other countries subsequently involved in the epidemic. Over a dozen such incidents were reported in Japan and confirmed serologically or by direct virus isolation. Although they must have seeded the virus at least in and near the ports of importation, a true epidemic of Hong Kong influenza did not start until October. It spread gradually, first to the larger and more crowded cities and then to smaller urban areas, but in a sporadic manner and without massive involvement of the rural areas. This was in marked contrast to an influenza B epidemic that affected the whole country during the same period-September-October 1968 to March 1969-and also in contrast to the 1957-58 Asian influenza epidemic.

Disease Outbreaks↗
PubMed1969

Interpretation of influenza antibody patterns in man. Existence and significance of Hong Kong antibody in old people prior to the Hong Kong influenza epidemic.

In sera drawn from persons over 72 years of age living in an old people's home in Japan there was found to be a certain degree of antibody to Hong Kong virus before the outbreak of the Hong Kong influenza epidemic in that country. The Hong Kong antibody titres in this group showed no correlation with the titres of simultaneously circulating classical A2 antibody. These findings suggest that some 70 years ago there may have been an epidemic influenza era during which a type of influenza A virus prevailed that was similar in antigenic structure to the Hong Kong type. A similar suggestion was made by workers in the Netherlands in connexion with the classical A2 influenza on the occasion of its appearance about 10 years ago. In view of the time lag between their findings and the present findings in Japan, the author suggests that an "ancient Hong Kong influenza era" may have followed the "ancient A2 influenza era", which may be supposed to have lasted about 10 years.

Age Factors↗
PubMed1967

Studies on cholera carriers.

Cholera carrier studies in the Philippines in 1964-66 showed a prevalence rate of 21.7% among household contacts of cholera patients, and 8.4% in occupants of houses next door to one where a cholera patient lived, as opposed to 0.34% in the general population. The duration of the carrier state among 19 household carriers isolated for examination varied from 5 to 19 days. The vibrio concentration in the stool of contact carriers was 10(2)-15(5) per gram, as compared with 10(6)-19(9) per ml of rice-water stool in cholera cases.The agglutinin titre increased with time for carriers, as it does for patients. It declined to a very low level 8-12 weeks after recovery, with the exception of one proved long-term carrier.The strains isolated from carriers were identical in all respects, including virulence in infant rabbits, with strains isolated from patients-except that 3 carrier strains were rough.

Adolescent↗
PubMedDate not supplied

Antigenic variation of influenza viruses isolated from the recent epidemics.

In the winters of 1975-76 and 1976-77 there were fairly heavy epidemics of influenza in Japan, and on those occasions considerable discussions were held on the efficacy of influenza vaccine in connection with the variability of antigenic structure of the influenza virus. The type of the virus which prevailed in the winter of 1975-76 belonged to type A, but detailed antigenic analysis revealed that there had been two main antigenic types somewhat but definitely distinguishable from each other, the one is the well-known A/Victoria/75 type while the other is A/Tokyo/75 type. This epidemic seems to have started with the latter type, but soon the two types of virus prevailed hand in hand until the late part of the epidemic when the type A/Victoria/75 became overwhelming. The virus for the vaccine was however A/Tokyo/6/73 for that season, which is antigenically considerably different from both of these two strains. In the beginning of 1976, namely at the end of the epidemic season of type A, a few scattered epidemics due to type B influenza were reported from some parts of Japan. The result of antigenic analysis found that the virus belonged to B/Hong Kong/72 type, though showing some degree of antigenic schift. The same type of virus caused the epidemic of the winter 1976-77, which was considerably wide-spread and developed unexpectedly large number of cases. There were active discussion on the effectiveness of vaccine, of which B type was B/Gifu/1/73, recovered from the fairly large epidemic in 1973, and belonging to B/Hong Kong/72.

Antibodies, Viral↗
PubMedDate not supplied

Serological and virological investigations fo orthomyxovirus in birds in South-East Asian area.

We have previously reported that some species of migrating ducks (pintail, mallard, widgeon and falcated teal) possess in their sera antibodies against H antigens of human or avian influenza viruses. Such findings have also been reported from other workers, and the appearance of new types of influenza viruses accompanied by outbreaks of new influenza pandemics, or circulation of influenza virus antigens in animals, birds and humans have been discussed on the basis of such findings. Recently a number of orthomyxoviruses have been isolated from wild birds such as myna, banded parakeets, etc. imported from India and some areas of South-East Asia. Some of them have H antigens not recognized previously, and some are found to have more or less common reactions with human H3 antigen, and consequently antigens Hav 7 and Heq 2, which are known to show cross-reaction with H3. The significance of such a fact in connection with the appearance of a new influenza pandemic is discussed.

Animals↗