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Biomedical subjects

H G Neumann

Publications and source records attributed to H G Neumann.

At least 127 records · Page 7Linked to original sources
PubMed1975

[Clinical pathological studies of the microcarcinoma cervicis uteri (author's transl)].

1. In 232 diagnostical cervix-conisations (almost exclusively on account of positive papsmears) there were 119 carcinomata in situ and 17 microcarcinomata. In accordance and in comparison with other investigators the frequency of microcarcinoma - related to carcinoma in situ - runs up to approximately to 14%. Microcarcinoma was found in 6% of dysplasia and in 10% of all carcinomata in situ. 2. For early clinical diagnosis (for instance papsmears and colposcopy) as well as for therapy the topographical distribution of microcarcinoma is of importance; they have been found almost exclusively on the upper part of the uterine orifice. The treatment of microcarcinoma by means of conisation is being evuluated. An individually differentiated operative therapy is aimed at, by no means, however, the so-called "radical cancer-therapy". 3. Observations concerning cancerogenesis of the carcinoma cervicis are not only of theoretical interest. The "oligophasic" cancerogenesis from dysplasia has been observed - about one fifth of all cases of microcarcinomata came into existence that way. Relatively often a cytotest showed in these cases a Papanicolaou group III. The latter fact should be taken into account in our present time for a differential cytology.

Carcinoma↗
PubMed1975

[Problems in the indication for hysterectomy post conization].

The importance of histo-pathological diagnosis after conisation of the Cervix uteri in view of hysterectomia post conisation is discussed (94 Carcinomata in situ, 53 cases of dysplasia and 13 microcarcinomata). If there is a modern technique of coldknife-conisation, an intensive histo-pathological diagnostic regime and the possibility of cytological and colposcopical control, hysterectomia is not necessary in cases of complete removal of carcinoma in situ by conisation.

Carcinoma in Situ↗
PubMed1975

[Organization of mass-screening for early detection of cervical cancer and its precancerous conditions. I. report: Demonstration of a computer assisted mass-screening program (Model Rostock) (author's transl)].

Gynecological mass-screening leads to a decrease of prevalence and incidence of cervical cancer and precancerous conditions. In Rostock a program for early detection of cervical cancer was developed. Organization, application of computer in this model and the expenses of a computer assisted mass-screening-program are discussed. In order to facilitate comparison between various centers, a generally accepted classification and terminology of colposcopic, cytologic and histologic findings are essential. First epidemiological results of Rostock's women are demonstrated to characterize the screened population.

Costs and Cost Analysis↗
PubMed1975

[Organization of mass-screening for early detection of cervical cancer and its precancerous conditions. II. report: Practical experience with a computer assisted mass-screening program (Model Rostock) (author's transl)].

Two years experiences with a computerassisted program for early detection of prestages and early cervical cancer in Rostock-city are reported. From 43.000 women invited to take part in the examination, 27.028 = 65% finally cooperated. Pathological Pap-smears were found in 134 cases (= 0,52%). Histological examination in 51 cases (= 0,2%) showed 1 Erosio vera (false positive), 9 severe dysplasia, 30 carcinomata in situ, 3 early invasions (microinvasive cancer), 3 microcarcinoma and 5 macrocarcinoma. Accessory findings were seen in 10,2%. A good organized mass-screening-system with unique nomenclature, diagnostic and treatment of cervical cancer and its prestages gives the best supposition to cut down its rate of incidence.

Adult↗
PubMed1974

Histological studies on the topography in dysplasia and carcinoma in situ of the extocervix (author's transl).

In 62 cases of dysplasia and 104 carcinomata in situ (in addition 15 microcarcinomata) a topographic localization on the surface of the portio uteri is demonstrated. The paraffin embedded undivided cones were cut into slices with constant distances of 0.75 mm. There are different types of localization. We observed in nearly 50% of carcinomata in situ and in nearly 66% of dysplasia a circular distribution. 20% of the carcinomata in situ were found in a largeness of a quarter of the surface of portio or smaller. The strongest alterations in carcinomata in situ (and microcarcinomata) are localized on the upper part of the uterine orifice.

Carcinoma in Situ↗