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Biomedical subjects

H Hager

Publications and source records attributed to H Hager.

At least 73 records · Page 4Linked to original sources
PubMed1976

Alanine formation and alanine aminotransferase activity in the nerve tissue with proliferating macroglia.

In the nerve tissue with proliferating macroglia cells were observed a lowered oxygen consumption, an increased aerobic glycolysis and alanine formation and a higher alanine aminotransferase and glutamate dehydrogenase activity than in the control tissue in the homogenates and in the cell sap fraction. The substrate saturation curves, apparent Km and pH optimum values in the tissue with proliferating macroglia and in the control did not differ from one another. The authors assume that a higher alanine aminotransferase activity in the tissue with macroglia proliferation can reflect either a higher synthesis of the enzyme in the altered tissue, or a predominance of glial elements in the altered tissue possessing a higher alanine aminotransferase activity than the nerve cells.

Alanine↗
PubMed1976

[Problems in treatment of ocular and cerebral vascular disturbances (author's transl)].

With regard to a paper of Leydhecker the basic principles of a combined treatment of ocular and cerebral vascular disturbances with Strophanthin, resp. Digitalis, Vasodilatators, and Hydrocortisone medicaments are again discussed. The influence of hypoxia in vasodilatation, the confirmation of alterations in visual field, as well as the effect of decreased blood viscosity on the circulation are discussed. The most important item, cardiotherapy, is emphasized once again. The peripheral effects of Strophanthin, especially on the brain, are confirmed by communications of other authors. The prognosis of this polypragmatic therapy in long-term observations is also limited.

Blood Viscosity↗
PubMed1975

The corpus luteum periodicum in the bitch: histochemical and biochemical investigations during different phases of the cycle.

The corpus luteum periodicum (c.l.p.) of the bitch was studied using enzyme histochemistry, clinical and biochemical methods. Assessment of variations of the serum progesterone level during different stages of the ovarian cycle and the study of enzymatic activity of the luteal tissue furnished informations on vitality and biosynthetic capacity of luteinizing cells: The period of functional activity of the c.l.p. nearly ceased about day 60 of the cycle (proestrus included) in the animals examined. In the light microscope the neo-synthesis of progesterone in the c.l.-tissue can be made visible by histochemical demonstration of the activity of Delta(5)-3 beta-hydroxysteroiddehydrogenase (3 beta-HSD) only up to a progesterone level exceeding 6.7 ng/ml plasma. The data obtained contribute to our baseline knowledge of the mechanism involved in the etiology of pseudopregnancylike conditions in the bitch.

Anestrus↗
PubMed1975

EM findings on the source of reactive microglia on the mammalian brain.

In traumatic brain lesions microglia cells are often plastered on the outer surface of capillaries. Basement membranes delimit these juxtacepillary cells from pericytes and endothelial cells. In altered nervous tissue many stages in the activation of pericytes may be seen at the same time. It is clearly demonstrable that these pericytes attack the basement membrane vigorously from inside. After penetration of the basement membrane these cells propel themselves between the perivascular feet processes of astrocytes and squeeze between the intracellular gaps, becoming surrounded by the cell processes of the neruopil. The observations suggest that in reactive stages in microglia cells may, at least in part, originate from the perivascular mesenchymal tissue.

Animals↗
PubMed1975

Central neuroblastic tumour associated with smooth muscle fibers. A study in the optic and electron microscopes.

The present paper is a study of a microcystic intraspinal tumour that developed in a 4-year-old child. The histologic examination showed the presence of neuroblastic elements developing next to smooth muscle fibers. The tumour had diffusely invaded the meninges, presenting a marked collagen reaction. Ultrastructurally, the neuroblastic elements exhibited an arrangement proper to the neural tube and the presence of a series of osmiophil neurosecretory dense-core vesicles. The fine structural morphology of the smooth muscle fibers was clearly revealed, the cells containing microfibrils and being delimited by a basement membrane. The muscular fibers were visibly in contact with the blood vessels. These aspects demonstrate that the medullomyoblastoma is a malignant bidermal teratoid tumour of the central nervous system. Dysgenesis of the ectomesenchyma may be considered to stand at the basis of the development of this type of tumour.

Child, Preschool↗
PubMed1975

Scanning electron microscopy in ophthalmology.

In the context the technique of the scanning electron microscopy is described and the results are shown gained by the scanning electron microscope in ophthalmology. It is pointed out that questions specific to surface can be answered quicker and easier, if superificial microscopy together with the scanning electron microscope is used an additional source of information. Scanning electron optical pictures are very useful for ophthalmologic science.

Ciliary Body↗
PubMed1975

[Pigment glaucoma. Scanning-electronmicroscopic findings. (author's transl)].

In case of a patient suffering from pigment glaucoma trabeculectomy was performed on both eyes. In one trabecular section the outer wall of Schlemm's canal, and in the other the trabecular framework were investigated by scanning-electronmicroscopy. The intertrabecular spaces were largely blocked by pigment granula, which, in some places, were stored in the clump cells of the iris. Even the outer wall of Schlemm's canal was dotted with pigment granula. The scanning-electronmicroscopic findings revealed the pigmental drainage blocking of the aqueous humour and explained the acute pressure rise in the pigment glaucoma with wide iridocorneal angle by an acute obstruction of the already largely blocked intertrabecular spaces.

Adult↗
PubMed1975

[Lasermicrosurgery in glaucoma (Lasertrabeculopuncture I1LTP], tangential irisbasecoagulation [TLC], removal of miosis and shifting of pupils) (author's transl)].

The long-term results of Lasertrabeculopuncture (LTP) and of tangential irisbasecoagulation (TIC) according to experience of 4 years are presented and critically discussed in comparison with the reports of other authors. The removal of miosis and the shifting of displaced pupils in glaucomatous and cataract eyes is demonstrated. The long-term results of other interventions in glaucoma by lasermicrosurgery are announced.

Glaucoma↗