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Biomedical subjects

H Iizumi

Publications and source records attributed to H Iizumi.

6 recordsLinked to original sources

Effect of physical training on thrombotic tendency in rats: decrease in thrombotic tendency measured by the He-Ne laser-induced thrombus formation method.

The effect of physical training on thrombotic tendency was assessed in rats. Exercise was done on a flat treadmill for 30 min at a rate of 1,400 m/h (submaximal speed), 5 times a week for either 1.5 or 3 months. The thrombotic tendency was measured by the He-Ne laser-induced thrombus formation method in microvessels of mesentery, i.e. measurement of the number of laser irradiations necessary to induce stasis of blood flow by occlusive thrombus formation. An increase in the number of irradiations necessary to induce occlusive thrombus formation was observed in arterioles, but not in venules after physical training for 1.5 and 3 months.

Animals

Effect of food consumption pattern on total serum cholesterol level: a methodological approach.

The food intake and serum cholesterol levels of 60 healthy, middle-aged inhabitants of Kobe city were surveyed from 1974 to 1981. We attempted to estimate the serum cholesterol level in which food consumption patterns (8-factor scores) were chosen as dietary indicators. Every two years, multiple regression analysis was applied cross-sectionally for males and females, using the eight factor scores as independent variables and the total serum cholesterol level as a dependent variable. The multiple regression coefficients based on the factors were significant for both males and females. Reproducibility of the standard partial regression coefficients, beta, for females was also high. We obtained a formula for estimating serum cholesterol level based on the scores of Factor 1 (staple foods), F5 (prepared foods), F6 (traditional Japanese foods), F7 (vegetable oil) and F8 (nutrition-consciousness): multiple regression coefficient R = 0.56 and coefficient of determination R2 = 0.31. The multiple regression equation indicated that serum cholesterol level increased with the combined effects of the uniformity of the food life, westernized-type food consumption, concern for nutrition and a relatively low intake of vegetable oil.

Adult

Eleven-year follow-up of changes in individuals' food consumption patterns.

In 101 healthy middle-aged persons of both sexes, changes in dietary were followed up for 11 years 1974 to 1984. As dietary indicators, the food consumption pattern, 8 factors obtained by factor analysis, was used. The factors were evaluated for changes with age in each person and each sex. Changes with age were observed for the food consumption patterns: There was a general tendency in the group for the staple food factor to change in the direction of a Westernized food the same time, the group generally changed in the direction of less intake of sweets and of animal fats. From the standpoint of nutrients, the changes over this period were a decrease in the energy intake, in the percentage of energy from carbohydrate, of energy from alcohol, which caused a slight increase in the percentage of energy from protein and fat. The main factors in the changes was physiological changes that accompany the process of aging, changes in the consciousness of health, and changes in the food environment.

Adult

Physical conditions affecting food consumption patterns.

From the point of view of food counseling, we studied the coefficients of cross correlation in the relationship of physical conditions and eating behavior. For the 11 years from 1974 to 1984, we monitored 101 healthy middle-aged persons in terms of the food intake and several indicators of health. Of the various indicators, the systolic blood pressure (SBP), the diastolic blood pressure (DBP), total cholesterol in the serum (TOTAL-C), beta-lipoprotein (beta-LIPO), and relative weight, all risk factors in atherosclerosis, were used as physical conditions. For the diet indicator, we used eight factors in the food consumption pattern. We calculated the correlation for individuals between these indicators. The clinical data, with the exception of systolic blood pressure, affected the food consumption pattern, and a mutual feedback between the physical conditions and the diet seemed to be possible. The correspondence for the food intake of individuals to physical conditions did not contradict current knowledge about nutrition.

Adult