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Biomedical subjects

H J Spjut

Publications and source records attributed to H J Spjut.

At least 73 records · Page 4Linked to original sources
PubMed1976

Intramural gastric abscess.

Two patients who underwent surgical resection of intramural gastric abscesses are described. Intramural gastric abscesses is a rare problem that simulates more common surgical conditions. The salient features of the symptoms, signs, and findings are reviewed.

Abscess↗
PubMed1976

Diffuse malignant mesothelioma.

Thirteen cases of diffuse malignant mesothelioma, 12 pleural and one peritoneal, were examined and reviewed from the clinical and morphologic points of view. The most frequent symptom and sign were pain and effusion. Periods of survival varied, with one patient surviving 11 years despite morphologic features of the pleural tumor. The diagnosis can be made only on the basis of excised tumor tissue. The best control of the tumor is attained by repeated surgical removal. Neither radiation nor chemotherapy altered significantly the growth of the tumors.

Adult↗
PubMed1976

Ischemic necrosis of multiple major joints: report of two cases.

Two patients with idiopathic ischemic necrosis of multiple major joints are described. One had both humeral and femoral heads involved and the other had involvement of the humeral heads and one femoral head. These combinations are uncommon. Specific causes could not be found in the histories, although one patient was a chronic alcoholic and and other was severely allergic to coffee dust. In the care and follow-up of patients with ischemic necrosis, attention should be given to the possibility of involvement of multiple major joints.

Femur Head Necrosis↗
PubMed1976

Hepatic adenoma: a possible complication of oral contraceptive therapy.

Three cases of hepatic adenoma occurred in women, two of whom were taking oral contraceptive medication. The clinical and pathologic data from these and previously reported cases are reviewed. The possible causal relationship between the development of hepatic adenomas and the use of oral contraceptives is explored.

Adenoma↗
PubMed1975

Malignant mesenchymoma. Case report with electron microscopic study.

A malignant tumor from the thigh of a 65-year-old man was examined by light and electron microscopy. The tumor was diagnosed by light microscopy as malignant mesenchymoma with prevalence of leiomyosarcomatous or liposarcomatous components, but electron microscopic study revealed that the basic cell was similar to chondroblastic or osteoblastic cells. However, a precise ultrastructural classification of the tumor cells was not possible, since the majority of the cells had mixed features. The histogenesis, differentiation, and relation to prognosis are discussed.

Aged↗
PubMed1975

Bronchiolo-alveolar carcinoma-cell of origin.

Bronchiolo-alveolar carcinoma is the least common of the primary pulmonary carcinomas, and there is controversy as to its cell of origin. In this light- and electron microscopic study of five bronchiolo-alveolar carcinomas, at least two cell types were found, both of bronchiolar origin. One cell type is a metaplastic bronchiolar mucous cell and the other a bronchiolar stem cell that has ultrastructural features of both the respiratory ciliated and the respiratory nonciliated ("Clara") cell. It would not be unusual if tumors of the bronchiolo-alveolar region differentiate into cells of either the bronchiole or the alveolus, for embryologically they have a common origin. However, as information about the ultrastructure of these tumors accumulates, it is becoming apparent that an alveolar-cell carcinoma must be a rare occurrence. Hyperplastic Type II aleveolar epithelial cells may be found about the margins of these tumors and can be mistaken for the neoplastic cells.

Adenocarcinoma, Bronchiolo-Alveolar↗
PubMed1975

Nuclear magnetic resonance studies on human breast dysplasias and neoplasms.

The ability of nuclear magnetic resonance (NMR) spectroscopy to distinguish normal, diseased non-neoplastic, and neoplastic human breast tissues was investigated with T1 and T2 relaxation times used. The results indicated that NMR relaxation times could distinguish between the mean values of breast neoplasms and other diseased or normal tissues, with P values less than 0.001. Given a single sample, the probability of classifying it nonneoplastic or carcinoma could be accomplished with 85% confidence. For human breast tissues, the relaxation time T2 may be more discriminating that T1. These results support the view that the use of NMR spectroscopy in cancer detection may be of significant value and warrants considerable more interest and effort to determine the beneficial applications and limits of this technology.

Adenocarcinoma↗