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Biomedical subjects

H Kraeft

Publications and source records attributed to H Kraeft.

24 records · Page 2Linked to original sources

[Pediatric problems arising from surgery of the pancreas in childhood (author's transl)].

The annular pancreas which is responsible for one third of the cases of duodenal obstruction plays a central role in pancreatic malformations. Therapy of choice is a duodeno-duodenostomy. Prognosis is deteriorated by frequent premature delivery, Down's syndrome and associated malformations. Among pancreatic tumors the congenital pancreatic cyst, the cysto-papillary adenoma and the insulinoma are particularly considered the latter in connection with the discussion of hyperinsulinism which also nesidioblastosis is associated. Pancreatic tumors to require surgical therapy and a subtotal excision of the pancreas is frequently necessary in nesidioblastosis. Besides pancreatitis which is diagnosed in Germany also pancreatic rupture with subsequent posttraumatic pancreatitis leading to pancreatic pseudocysts is discussed. There are no deaths after isolated pancreatic trauma or surgery of pancreatic pseudocysts.

Adenoma, Islet Cell↗

[Effect of alpha-blocking agents on the internal anal sphincter muscle].

47 patients with functional chronic constipation associated with an achalasia of the anal sphincter were treated with the alpha blocking agent Phenoxybenzamin. Dosages were used according to the manufacturers' instructions. 29 of the children were completely cured. There was significant improvement in a further 13 children and only 5 patients showed no improvement. Treatment failures were associated with additional severe psychological disturbances for which psycho-therapeutic management was required.

Adolescent↗

Causes of postoperative mortality in anorectal malformations: analysis and conclusions regarding therapy.

We studied 279 cases of rectal malformation in the hospitals of Munich, Berne and Lucerne in order to evaluate the mortality in this condition. 51 children died, an overall mortality of 18.2%. Three fourths of these fatalities were due to associated severe malformations, prematurity or brain damage respectively. Eleven children died because of postoperative infections. In the future the use of appropriate measures to avoid these complications should be attempted.

Abnormalities, Multiple↗

[Results of inadequate aftercare following surgical correction of proctatresia (author's transl)].

For deep proctatresia, postoperative aftercare consisting of adequate, long-term bougienage is important. On the basis of 10 cases, it was shown that inadequate postoperative bougienage for proctatresia leads to formation of a megacolon and to overflow incontinence. The incontinence can then only be controlled by carrying out a proctectomy and a sigmoidectomy together with surgical formation of the gracilis. This proved to be satisfactory for all 10 cases presented.

Anal Canal↗

Influence of gastrostomy on the colonization of the stomach: impact on neonatal septicaemia.

Quantitative bacterial counts were carried out on 161 gastric aspirates of 65 neonates with gastrostomy. In comparison to 101 controls--cultures of premature infants without gastrostomy--Enterobacteriaceae, enterococci, Pseudomonas and Candida were found far more frequently (p less than 0.01). The colonization of the stomach was influenced by the duration of gastrostomy and by the pH of the gastric juice but not by systemic antibiotic therapy or the kind of food. Six newborns with gastrostomy developed septicaemia caused by the same organisms as we had found in elevated numbers in their gastric aspirates. The influence of non-absorbable antibiotics was studied prospectively in 72 gastric aspirates and 48 stool specimens. There was no highly significant difference between infants who had been treated with these antibiotics and those who had not.

Anti-Bacterial Agents↗