PubMed Health⌕ Search

Biomedical subjects

H M Fullmer

Publications and source records attributed to H M Fullmer.

At least 37 records · Page 2Linked to original sources

Collagenase: localization in polymorphonuclear leukocyte granules in the rabbit.

Polymorphonuclear leukocyte granules were submitted to zonal fractionation through a discontinuous sucrose gradient. Azurophilic and specific granules were enzymatically characterized by peroxidase and alkaline phosphatase activity, respectively. The enzymes formed modal distributions like those reported by others. Collagenase activity was consistently associated with the specific granules containing alkaline phosphatase.

Alkaline Phosphatase↗

Human granulocyte collagenase.

A collagenase, operative at neutral and alkaline pH, has been extracted from the granule fraction of human granulocytic leukocytes. It digests reconstituted collagen fibrils and reduces the viscosity of collagen solutions. Cleavage of collagen in solution with purified enzyme produces the discrete products characteristic of other animal collagenases.

Acrylic Resins↗