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Biomedical subjects

H M Khan

Publications and source records attributed to H M Khan.

29 records · Page 2Linked to original sources
PubMed1985

Experimental infection of rhesus monkeys with Entamoeba histolytica mimics human infection.

Experimental infection of Entamoeba histolytica was successfully established in rhesus monkeys (Macaca mulatta). Parasites of proven pathogenicity maintained through liver passage in hamsters were used in this study. Laparotomized monkeys were inoculated intracecally/intrahepatically with trophozoites, or by oral administration of cysts (2000 cysts/ml). The cysts were isolated from an infected human stool sample. Formation of typical amebic lesions in the inoculated tissues along with alterations in hematologic indices were studied in the infected monkeys. All the experimentally inoculated monkeys showed leukocytosis and mild neutrophilia, while the hemoglobin content and levels of blood sugar and blood urea remained unaltered during the post-infection period. Specific antiamebic antibodies were readily detectable in post-infected sera.

Amebiasis↗
PubMed1984

Clinical therapeutic analysis of vitiligo phase--II.

The incidence of vitiligo varies from country to country. In the present study, seventy cases of vitiligo have been studied from skin out patient department of the Institute of Post-graduate Medicine & Research over a period of 2 years. The prevalence rate of vitiligo among the total out patient attendent was 0.4 per cent. 85 per cent of the cases belonged to the age group to 11-40 years. Male and female ratio was 2:1. Precipitating factors like physical injury, mental stress and strain had close link with development of skin lesion. In 11.4 per cent cases near relations were involved. Skin lesions according to the site showed lower extremity to be the maximally involved area and the genital areas were least involved.

Adolescent↗
PubMed1983

Incidence of cutaneous diphtheria in Bangladesh.

Corynebacterium diphtheriae (C. diphtheriae) was isolated from 23 (7%) skin ulcers out of 327 cases studied. Eight (33%) of the 23 positive cases belonged to the age group of 6 to 10 years. Of the 19 strains of C. diphtheriae typed, 18 (95%) were gravis and of which 14 (77%) were toxigenic. More than 90% of the C. diphtheriae positive ulcer cases had serum anti-toxin level at or above the protective level as against 49% of control. No diphtheria bacilli were isolated from throat of any of the skin positive cases. All the ulcers from which C. diphtheriae were isolated also harboured other definite wound pathogens. It is believed that the presence of toxigenic C. diphtheriae in skin wound might play an important role in the spread of faucial diphtheriae. It is evident from serum anti-toxin level that infected persons develop natural immunity.

Adolescent↗
PubMed1982

Incidence of urethritis in Bangladesh.

Urethritis is either gonococcal or non-gonococcal. This paper describes the investigation of 286 cases of urethral or vaginal discharges, dysuria or urethral irritation. Non-gonococcal urethritis (NGU) was found to be the commonest form of urethritis accounting for 65.05 per cent of cases. Gonococcal urethritis (GU) and abacterial urethritis were accounted for 24.47 per cent and 10.48 per cent of cases respectively. No history of sexual exposure was found in 21.27 per cent of cases with NGU, whereas this was invariably present in cases of GU. This may indicate that in at least some of the patients with NGU, the disease may not be sexually transmitted. This point needs further study.

Adolescent↗
PubMed1977

Post-Kala-azar dermal leishmaniasis ( a review of 10 cases).

Ten cases of Post-Kala-azar Dermal Leishmaniasis (PKDL) have been studied. The sites of involvement and morphological character have been noted. Skin scraping, biopsy, serological and biochemical changes have been looked for. Presence of visceral leishmaniasis along with PKDL had been searched. Response to therapy with antimony compounds have been observed and found satisfactory. Visceral leishmaniasis although not frequent now a days, the incidence of PKDL is still prevalent to some extent in this country.

Adolescent↗
PubMed1975

Absorption and elimination of photodieldrin by Daphania and goldfish.

The alga, Ankistrodesmus spiralis, becomes saturated with photodieldrin in 8 hours. The Daphnia whether contaminated by feeding on the algae saturated with photodieldrin or by directly absorbing this insecticide eliminate about 50 per cent of the absorbed photodieldrin in 4 days which increases up to 70 per cent in 7 days. However, continuous exposure of daphnids to photodieldrin results in increased absorption and accumulation of this insecticide. Transfer of the goldfish contaminated with photodieldrin to clean water results in initial elimination in 24 hours whose rate in is then is then subsequently reduced. These two organisms are thus capable of eliminating their body residues of photodieldrin, the "terminal residue: of dieldrin, if their environment is decontaminated.

Absorption↗