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Biomedical subjects

H Mathies

Publications and source records attributed to H Mathies.

At least 19 recordsLinked to original sources

[Guideline for the joint swelling symptom--primary physician problem management and referral indications. German Society of Rheumatology "Quality Assurance" Committee].

The guideline "Joint Swelling" is addressed to primary care physicians--general practitioners, internists or orthopedists without special experience in rheumatology. It provides a framework for interviewing patients, as well as for physical, laboratory and imaging examinations and for selection of treatment appropriate to the level of primary care. Situations which call for urgent evaluation and criteria for referral to rheumatologists are described. The appendix contains comments on signs and symptoms to differentiate arthralgia from joint swelling and on the diagnostic value of a history of joint swelling without confirmation by the physician. Further recommendations for the evaluation of patient history and physical and technical examinations are given in a tabular form. The significance of laboratory and imaging procedures is discussed.

Arthritis, Rheumatoid↗

[Expert assessment of psychosomatic disorders in rheumatology].

There are often big problems regarding expert evidences of psychosomatic clinical pictures, because, contrary to the complaints expressed and perceived by the patient, somatic findings are not evident to justify a permanent disablement. Nearly without exception it is a question of chronified cases of psychosomatic complaints up to real psychoneuroses. The diagnosis and delimination from a simulation is difficult and is frequently failed. Without doubt there are cases, in which only the psychic component determines the vocational disablement.

Arthritis, Rheumatoid↗

[HLA B27-associated rheumatic diseases from the clinical viewpoint].

On the basis of the description of the possible variable courses and symptoms of ankylosing spondylitis, Reiter's syndrome, and reactive arthritides (spondarthritides) frequently produced by intestinal infections, all of which show HLA B27 as the predisposing hereditary antigen in about 90% of the cases, it is discussed whether these conditions represent a disease entity in which additional unknown factors determine the expression and the tendency of the course of the disease.

Arthritis, Reactive↗

[Non-steroidal antirheumatic agents - questions of the clinician to the pharmacologist].

The problems of clinical application and effects of the non-steroidal antirheumatic drugs have been critically described and pointed at known pharmacological data and clinical publications. Especially still not sufficiently examined connections are emphasized, because their examination could contribute to an aimed use of the antirheumatic drugs. Furthermore the existing declarations concerning the clinical efficacy and the comparison of the effects are critically discussed with regard to their validity. Suitable presuppositions for subsequent trials and for the interpretation of their results are given.

Anti-Inflammatory Agents, Non-Steroidal↗

[Prednisolone reduction by benoxaprofen].

The prednisolone sparing effect of benoxaprofen has been examined in only 13 cases of rheumatoid arthritis. The examination was terminated prematurely because of an accumulation of side effects of the skin. The results of these 13 cases are not significant, but the drug seems to show a relatively high mean value of its prednisolone sparing effect but it seems to cause a high proportion of side effects, especially of the skin. This preliminary result should be reported in regard to possibly following studies with simular observations.

Anti-Inflammatory Agents↗