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Biomedical subjects

H Meffert

Publications and source records attributed to H Meffert.

At least 91 records · Page 5Linked to original sources
PubMed1982

Polyclonal B cell activation in the acute phase of systemic lupus erythematosus--aspects of pathogenic significance.

B lymphocytes from patients suffering from systemic lupus erythematosus show increasing rates of spontaneous transformation in prolonged cultivation (144 hr). An additional B cell stimulation could be detected following the addition of sera from lupus erythematosus patients (isolated during the acute phase of disease) to the culture medium. In addition enriched mitogenic serum components from lupus sera increase the 3H-thymidine uptake of Brucella abortus primed B cells of healthy controls. The incorporation of 3H-thymidine with respect to the Brucella antigen concentration is described.

B-Lymphocytes↗
PubMed1981

Incorporation of 14C-linoleic acid in cerebrosides of psoriatic and normal human skin.

Psoriasis is marked by loss of glycoalyx. Glycocalyx is composed of glycoproteins and glycolipids such as cerebrosides. It was shown that the incorporation of 14C-linoleic acid in cerebrosides of normal and psoriatic human skin is different. In psoriatic epidermis and corium the turnover of this fatty acid is significantly elevated. It is suggested that in psoriasis the epidermal cell is not able to build up a regular carbohydrate sequences of lipids because the false carbohydrate chain activates the degradation of glycolipids and in compensating for the increased degradation raises the synthesis rate of glycolipids.

Carbon Radioisotopes↗