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Biomedical subjects

H Ohe

Publications and source records attributed to H Ohe.

At least 55 records · Page 3Linked to original sources
PubMed1990

[Interferon-alpha producing capacities in prostatic cancer patients].

Interferon-alpha (IFN-alpha) producing capacity was measured in 47 patients with prostatic cancer by whole blood assay. The mean IFN-alpha producing capacity of prostatic cancer patients was 3657 IU/ml, which indicated a significantly (p less than 0.005) lower value than that in healthy male aged 50 years or more. IFN-alpha producing capacity in patients with Stage D disease was lower than that with Stage A, B or C. The higher the grade of the disease, the lower tended to be the capacity. A certain relationship was suspected between IFN-alpha producing capacity and the prognosis of each patient. In particular, in patients with prostatic cancer in Stage D, the prognosis was worse in low IFN-alpha producing capacity group (less than 3000 IU/ml) than in normal or high IFN-alpha producing capacity group (greater than or equal to 3000 IU/ml). It was considered that IFN-alpha producing capacity might be useful in developing the prognosis of patients with prostatic cancer.

Humans↗
PubMed1989

[Relationship between subjective symptom and presumed circle area ratio (PCAR) in benign prostatic hypertrophy].

Subjective symptoms on voiding were analysed in 419 subjects who were submitted to mass screening program for prostatic diseases by means of transrectal sonography, consisting of 296 normal subjects and 123 cases of benign prostatic hypertrophy (BPH). Subjective symptoms were encountered in about 70% of normal subjects and 80% of BPH cases. However, almost all normal subjects complained of single symptom, while many BPH cases of multiple symptoms. The frequency of subjective symptoms in BPH cases was significantly higher than that in normal subjects. Relationship between each subjective symptom and the presumed circle area ratio (PCAR) was evaluated in all cases of BPH. As the results, it was proved that the higher the PCAR was, the more the appearance of the urinary prolongation and nocturnal frequency were encountered. Moreover, it was presumed that these symptoms on voiding, especially the urinary prolongation, correlated closely with the degree of urinary obstruction in BPH patients.

Aged↗
PubMed1988

Kinetic analysis of prostatic volume in treating prostatic cancer and its predictability for prognosis.

Prostatic volume in patients with prostatic cancer diminished remarkably after castration according to measurements by transrectal sonography. These kinetic changes in prostatic volume were analyzed and a formula was applied to the regression curve. The reduction time (tau) in the formula, which is a constant representing the time interval required for the effective portion of the prostate to be reduced to one tenth, was thought to be a good index to predict the prognosis of the patients.

Cell Division↗
PubMed1988

Congenital saccular aneurysm of the superior vena cava.

A 69-year-old woman was admitted to our hospital for surgical treatment of a mediastinal mass. Midsternotomy was performed which revealed a saccular aneurysm of the superior vena cava, 6 cm in diameter, in the right superior mediastinum. Aneurysmectomy was done by dividing a 15 X 10 mm venous connection with the superior vena cava and the patient's postoperative course was uneventful.

Aged↗
PubMed1988

Dynamic study of nervous control on prostatic contraction and fluid excretion in the dog.

The effect of the section or stimulation of various nerves on prostatic contraction and fluid excretion was investigated dynamically in the dog using an apparatus devised in our laboratory. Prostatic contraction could be classified into two types from the pattern of the contracting wave. One was a prominent tonic contraction, designated as H-type contraction, observed typically after hypogastric nerve stimulation and followed always by prostatic fluid excretion. The other was a weak clonic contraction, designated as P-type contraction, occurring typically after pelvic nerve stimulation and accompanied by no fluid excretion. The periodical contraction of these two types was noticed even at rest. The H-type contraction was associated with fluid excretion with a mean rate of 0.3 ml./hr. The denervation both of the hypogastric and pelvic nerves showed no distinct influence on contraction and excretion in the resting condition. The pudendal nerve was demonstrated to have no significant effect on prostatic contraction and fluid excretion. From these results, it was considered that dynamic fluid excretion followed by prostatic contraction was regulated chiefly by sympathetic fibers from the hypogastric nerve and the physiological role of parasympathetic fibers from the pelvic nerve was something other than fluid excretion.

Animals↗
PubMed1988

Accuracy of digital palpation for size assessment of the prostate evaluated by transrectal sonography.

In order to clarify how precisely digital palpation gives information on prostatic size, evaluation of the size measurement of the prostate by means of transrectal sonography was performed on 1,543 subjects with various prostatic disorders. There was little agreement between the assessment of prostatic size by digital palpation and the ultrasonic measurement. The larger the prostate the less accurate was digital palpation. The prostatic size assessed by digital palpation was particularly dispersed widely in the prostate of 'hen's egg' size. It was proved that the size assessment by digital palpation was only effective statistically in a two-step differentiation, 'hen's egg' size and smaller. More complicated size classification was of little clinical value in digital palpation.

Evaluation Studies as Topic↗
PubMed1987

Kinetic evaluation of the effect of LHRH analog on prostatic cancer using transrectal ultrasonotomography.

The size of the prostate was measured in 11 patients with the prostatic cancer by means of transrectal ultrasonotomography after LHRH analog ([Ser(Bu)6] LHRH) treatment. Prostate volume changed parallel to serum testosterone (T) level and decreased by 17-62% compared with baseline after LHRH analog treatment for 4 months. Two different patterns were observed for the change in prostatic volume. Type A expanded transiently and then decreased gradually, while type B decreased continuously from the beginning with no expansion. After treatment for 4 months, the prostatic volume of type A was significantly less than that of type B. It is suggested that prostatic cancer showing a type A regression curve may be more sensitive to T, resulting in a better prognosis than type B.

Adenocarcinoma↗
PubMed1987

Comparative analysis of short-term and long-term prophylactic intravesical chemotherapy of superficial bladder cancer. Prospective, randomized, controlled studies of the Japanese Urological Cancer Research Group.

The Japanese Urological Cancer Research Group has conducted three randomized clinical studies on intravesical chemoprophylaxis of superficial bladder cancers. This paper presents a comparative analysis of the first and second of these. The protocol used in the first study was a so-called short-term schedule in which drugs (for group A, ADM 30 mg/30 ml; group B, ADM 20 mg/40 ml; group C, MMC 20 mg/40 ml; and group D, control) were administered twice a week for 4 weeks after transurethral resection (TUR), and in the second study a long-term schedule was used, in which drugs (for group E, ADM 30 mg/30 ml; group F, ADM 20 mg/40 ml; group G, MMC 20 mg/40 ml; and group H, control) were administered twice a week for 1 week, every 2 weeks for 7 weeks, monthly for 8 months, and finally once every 3 months for 1 year. In the first study 575 patients were evaluated and followed up for 5 years. The second study started 28 months later, and 607 patients were evaluated. A generally good prophylactic effect was obtained in the second study when the patients' backgrounds were adjusted in combination with the history and number of the tumors. The second study did not reveal any promoting or inhibitory effect on the progression of the recurrent tumors. There were no significant side effects in either study. The indications and the schedule for prophylactic intravesical chemotherapy should be more carefully studied.

Administration, Intravesical↗
PubMed1987

Development of benign prostatic hypertrophy estimated from ultrasonic measurement with long-term follow up.

Sixteen cases of benign prostatic hypertrophy (BPH) were followed up by the measurement of the prostatic weight using transrectal ultrasonotomography over a period of 7 years. In 3 cases (the 'increasing group') the weights increased remarkably, and in the remaining 13 cases (the 'stationary group') did not change very much during the period of observation. The rapid phase of increase in the prostatic weight in the 'increasing group' was observed only in their 6th decade. No special tendency was noticed with regard to age in the 'stationary group'. It is presumed that the enlargement of the hypertrophic prostate might occur rapidly in a short period, probably a few years in the 6th decade or before, and that after rapid enlargement, the weight of the prostate does not change very much.

Aged↗