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Biomedical subjects

H Ohe

Publications and source records attributed to H Ohe.

At least 73 records · Page 4Linked to original sources
PubMed1987

[Analgesic effect of calcitonin in patients with metastatic bone lesions from urogenital cancer].

The analgesic effect of eel-calcitonin (Elcitonin) was evaluated in 10 patients with metastatic bone lesions from urogenital cancer. Five patients had renal cell carcinoma, while the remaining 5 patients had prostatic cancer. Eel-calcitonin was injected intravenously to each patient at a dose of 80 units every day. The drug was markedly effective for 3 patients, effective for 4 patients and ineffective for 3 patients. The effect was better for prostatic cancer than renal cell carcinoma.

Aged↗
PubMed1986

Ultrasound findings in urolithiasis in the lower ureter.

Thirty-two cases of urolithiasis in the lower ureter, difficult to detect by ordinary X-ray studies, were diagnosed accurately by ultrasound. Stonelike echoes were easily detected on the ultrasonograms when the ureter of the affected side was dilated. Patients should be examined by ultrasound prior to invasive retrograde pyelography.

Aged↗
PubMed1986

Comparison of digital examination and transrectal ultrasonography for the diagnosis of prostatic cancer.

The ability to detect prostatic cancer by transrectal ultrasonography was evaluated in a prospective blind study of 216 men. The sensitivity of transrectal ultrasonography was 86 per cent but the specificity was only 41 per cent. Tumors less than 1 cm. in diameter were most difficult to detect by transrectal ultrasonography. The positive and negative predictive values of transrectal ultrasonography were 36 and 89 per cent, respectively. Abnormal scans that strongly suggested carcinoma were present in 10 per cent of the men who had a normal digital examination but no biopsy was performed. Transrectal ultrasound is a sensitive method to detect all but small prostatic tumors and it can detect tumors that are not evident by digital examination. To date, however, transrectal ultrasonography may be difficult to use for routine screening in the United States because of the low positive predictive value. Nevertheless, further investigation of this technique is warranted to define its role in improving the diagnosis of prostatic cancer.

Humans↗
PubMed1986

Evaluation of effect of treatment for primary lesions of stage D2 prostatic cancer by means of transrectal ultrasonotomography.

The effect of treatment for primary prostatic lesions of Stage D2 prostatic cancer was evaluated by means of transrectal ultrasonotomography and was compared with that for distant metastatic lesions. A new score system was introduced to assess the effect of treatment for the primary lesions of prostatic cancer from the ultrasonic findings of the prostate on a single examination after treatment. In 19 subjects evaluated as effective or moderate in the treatment of primary lesions, 9 were also evaluated as effective or moderate in the treatment of metastatic lesions, while 10 were judged as poor in the treatment of metastatic lesions. In 12 subjects which were evaluated as poor in the treatment of primary lesions, 3 were judged as moderate in the effect of treatment of metastatic lesions, while 9 were judged as poor. It was proved that the correct evaluation of the primary prostatic tumor was required to perform adequate treatment for Stage D2 prostatic cancer.

Combined Modality Therapy↗
PubMed1986

Experimental study on the regulation of testicular function by the cremaster reflex in rats.

The present study was performed to clarify the role of the cremaster reflex in regulating the testicular function in rats. The impairment of cremaster reflex by bilateral dissection of the genitofemoral nerves resulted in a decrease of testicular weight and degenerative changes of the semeniferous tubules in the rats kept in a cold room (4 degrees C), but not in the rats kept at room temperature (22 degrees C). The results indicate that the cremaster reflex contributes much to the temperature regulation of the testicle located within the scrotum.

Animals↗
PubMed1986

[Clinical study of cinoxacin in acute simple cystitis].

Cinoxacin (CINX) was administered twice a day for 7 consecutive days (400 mg X 2/day) to 34 female patients suffering from acute simple cystitis. The overall clinical efficacy was excellent in 15 cases (94%) and moderate in one case (6%) according to the criteria for clinical evaluation by the UTI committee. The efficacy was not determined in 18 cases. Bacteriological examination revealed 11 cases of single infection by E. coli, 2 cases of single infection by P. cepacia and S. epidermidis and one case of single infection by S. sunguis. MIC of E. coli ranged from 3.13 to 6.25 micrograms/ml. MIC of P. cepacia was 3.13 micrograms/ml and MIC of S. epidermidis more than 100 micrograms/ml. All the strains were eradicated with the efficacy of 100%. There was no relapse of acute simple cystitis in 16 cases after 7 days treatment of CINX. No serious side effects were recognized except for slight general fatigue and heart burn in 2 cases. It was thus concluded that CINX is clinically effective and safe for acute simple cystitis caused by E. coli and P. cepacia.

Acute Disease↗
PubMed1985

Preoperative evaluation of localized prostatic carcinoma by transrectal ultrasonography.

We evaluated 31 patients with clinically localized prostatic carcinoma by transrectal ultrasonography before radical prostatectomy. Results of ultrasonography were reviewed without previous knowledge of the extent of the disease and were compared to the pathological staging obtained by step section of the prostate. Preoperative transrectal ultrasonography was sensitive in detecting capsular and seminal vesicle involvement (89 and 100 per cent, respectively). However, the specificity of the method was low for capsular involvement (50 per cent), probably owing to the inability of this method to detect microscopic disease. This method is a valuable tool in the preoperative evaluation of patients with clinically localized prostatic carcinoma.

Carcinoma↗
PubMed1985

[Puncture technology and selective renal biopsy].

An experimental study of puncture technology for the kidney: We investigated the strength characteristics of tissues which are penetrated by the puncture needle for the kidney using a tension test. The tensile strength of the fascia, the muscle, the renal capsule, the renal parenchyma and the renal pelvis were 13.9, 1.1, 29.5, 0.5 and 21.4 kg/cm2, respectively. As the strengths differ, the needles for each tissue clearly need to be changed. Needle tip shape and needle material for kidney puncture were investigated by compression test, acryl resin injection into the renal vasculature, stereo-microscopy and scanning electron microscopy. These investigations revealed that the most suitable needle tip was a sharp cone shape, and material with a smooth surface and some flexibility such as Derlin seemed to be the most appropriate for the puncture needle for the kidney. Using the acryl resin injection method, stereo-microscopy and scanning electron microscopy, we studied the relative safety of single stage puncture and the repeated dilatation method to establish percutaneous nephrostomy. Single stage puncture seems to cause less damage to the kidney than the repeated dilatation method. Selective renal biopsy: A new puncture system using real-time ultrasound was developed at our clinic in 1978. The puncture procedure is monitored in 2 dimensional real-time images by a mechanical sector scanner equipped with an attachment for needle guidance. The application of the system to percutaneous renal biopsy is called "selective renal biopsy" because the specimen can be obtained selectively from any portion of the kidney.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1984

Transrectal ultrasonography of the prostate.

Transrectal prostatic ultrasonography has been performed in 203 patients within the last year. This new diagnostic modality has proven reliable in quantitating decrease in volume of the primary tumor following therapy in 71% of patients with prostatic carcinoma (10 of 14 patients) in whom long-term follow-up is available. In 12 patients staged prior to radical prostatectomy, prostatic ultrasonography was extremely valuable in detecting capsular involvement. This new diagnostic modality has significantly enhanced the staging capabilities in patients with localized prostatic carcinoma.

Follow-Up Studies↗
PubMed1984

Transrectal ultrasonotomography of the canine prostate.

We developed a new scanner for transrectal ultrasonotomography of the canine prostate. Using this scanner, a clear horizontal tomogram of the canine prostate was obtained for cross sections at every 2 mm. Prostatic volume was estimated as the sum of the volume of each section. Accordingly, the weight of the canine prostate could be accurately calculated from the volume and the specific gravity of the prostate.

Animals↗
PubMed1984

A mobile mass screening unit for prostatic disease.

A mobile unit for mass screening of prostatic disease using transrectal ultrasonotomography was developed in December 1980. In the following years we screened 1,396 males over 55 years of age. We have detected 463 cases [33.2%] of benign prostatic hypertrophy [BPH] and eight cases [0.6%] of prostatic cancer. The detection rate of BPH and malignancy of the prostate was shown to be very high. Thus, the unit promises to be of value in preventative medicine projects for prostatic disease in Japan.

Humans↗
PubMed1983

Staging of bladder tumors by transrectal ultrasonotomography and U.I. Octoson.

The staging of bladder tumors was performed in 100 cases by transrectal ultrasonotomography and in 44 cases by U.I. Octoson. Complete agreement between histology and ultrasound was obtained in 80% of the cases by the former method and in 73% by the latter method for tumors arising from the corpus of the bladder. However, agreement was obtained in only 38% of the cases by the former method and in 59% by the latter method for tumors arising from the apex and fundus of the bladder. The possibility of improving the agreement for tumors in the apex and fundus by introducing real-time transrectal linear scanning is suggested.

Humans↗