Kawasaki disease and Coxiella burneti.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to H P Lambert.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The effects of whooping cough were studied in 21 children admitted to hospital with the disease and in their families. The illness caused considerable distress to both child and family. Parents suffered especially from fears for the life and health of their child and from serious loss of sleep. Two months after admission the child's behaviour was still disturbed, but in most cases the rest of the family had returned to normal. There was much misunderstanding and misinformation about whooping cough among both parents and doctors.
Explore the source record for details and available documents.
Four hundred and sixty admissions for whooping cough to three hospitals between 1974-9 were reviewed. Many children had a long illness. More than half of them had severe or moderately severe coughing spasms and a quarter had pronounced feeding difficulties. The incidence of clinical pneumonia and convulsions was low and there were no deaths. The disease continues to be much more severe in infancy. There was some evidence that the disease declined in severity over the period studied. A number of factors including increased use of erythromycin may have contributed to this change.
Anthropometric measurements were made on 360 primary school children with a history of whooping cough and on 711 controls. Altogether 245 (68%) cases and 469 (66%) controls had taken tests of reading attainment and a smaller number had taken tests of intelligence. No significant differences were found between cases and controls in any of the anthropometric measurements nor in reading age or intelligence quotient after controlling for social class and parental smoking. Whooping cough is, in general, unlikely to cause subsequent deficiency in physical or mental development.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
360 primary-school children with a history of whooping-cough were shown to have experienced an excess of other chest illnesses compared with 711 controls. This susceptibility may, however, have antedated the whooping-cough. Current respiratory symptoms were also more common in children who had had whooping-cough, though no differences were found on physical examination. No differences were found in lung function between cases and controls. Whooping-cough, as experienced by British children in recent years, is unlikely to cause subsequent respiratory morbidity and does not result in impaired lung function in later childhood.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A patient with low back pain and recurrent Salmonella typhimurium septicaemia is described. Investigations revealed an aortic aneurysm, lumbar osteomyelitis and a psoas abscess. The importance of thorough investigation of patients with low back pain and salmonella septicaemia is emphasised.
Erythromycin and gentamicin were used to analyse the concept of bacterial synergy in an experimental model of acute appendicitis. Erythromycin given orally suppressed the aerobic flora other than the Enterobacteriaceae. When given by injection, a notable reduction in the counts of bacteroides and other anaerobic Gram-negative bacteria was also achieved. The addition of gentamicin, itself inactive against bacteroides, resulted in their total suppression. The implications of these findings are discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Bronchial secretions from 21 patients with moderate to severe chest infections were obtained by transtracheal aspiration. Six seriously ill patients showed greatly increased levels of amylase activity in the bronchial secretions compared with those found in the 15 less ill patients. This amylase was almost certainly derived from oropharyngeal contents and its presence suggests that aspiration may be more common in comatose and semi-comatose patients than is generally appreciated.