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Biomedical subjects

H P Seeliger

Publications and source records attributed to H P Seeliger.

At least 19 recordsLinked to original sources
PubMed1979

[Enteritis due to Escherichia coli O142 K86 H34 in a ward of premature infants. With a discussion on the problem of pathogenicity of "enteropathogenic serogroups of E. coli" (author's transl)].

E. coli O142 K86 H34 has been isolated from stool specimens of five babies in a ward of premature infants. Diarrheal stools were observed in two of them; one infant temporarily failed to gain weight, and the other developed a temporary loss of weight. Smooth stools observed in the third baby as well as asymptomatic infections in two others did not affect their normal development. The outbreak lasted 15 days; the source of infection and the mode of transmission remained unknown. The pathogenesis and importance of human diarrheal disease caused by E. coli is reviewed. Enteritis of adults and children due to enteroinvasive (EIEC) and enterotoxigenic (ETEC) strains is described. The etiological role of so-called "enteropathogenic E. coli" (EPEC), rejected increasingly during the past decade, has been demonstrated again in recent studies. Routine search for EPEC is suggested in cases of infantile enteritis in hospitals and other institutions.

Cross Infection↗
PubMed1977

[Prophylaxis of fungal contamination (author's transl)].

Increased contamination by facultative pathogens such as coliforms and related gram-negative bacteria and Candida albicans in hospital areas of risk endangers the benefits of medical care and causes great concern. The patient himself is the predominant source of nosocomial infections. Furthermore the medical staff, ward personnel, and contaminated environment must be incriminated. By proper decontamination of certain groups of high-risk patients and of their surroundings as well as by interrupting the microbial transfer at all levels, the present menace can be considerably reduced.

Aspergillus fumigatus↗
PubMed1977

Cryptococcosis: a diagnostic challenge.

Human cryptococcosis is an exogenous human infection of increasing frequency and growing importance. Early diagnosis is essential for the clinical outcome, no matter whether the infection is primary or secondary to underlying disease. Reliable and quick diagnostic methods are outlined and some pitfalls are discussed. Direct microscopy is essential, followed by cultivation procedures and serologic tests.

Agglutination Tests↗
PubMed1976

[Arthur Grumbach].

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Germany, West↗
PubMed1976

Macrophage function and host resistance against infection with Toxoplasma gondii.

The role of macrophages on the course of an infection with Toxoplasma gondii has been examined. Stimulation of macrophage function by killed Bordetella pertussis cells did not show any beneficial effect as an increased susceptibility became apparent. The functional blockade of macrophages by dextran sulfate or carbon particles did not result in a higher susceptibility of mice to the lethal primary infection with T. gondii. Thus in vivo macrophages apparently do not play an essential role as effector cells as they do in infections with other obligate intracellular infective organisms such as Listeria monocytogenes. The spleen is apparently of crucial importance for resistance against T. gondii infection, since death occurred earlier in splenectomized mice than in control animals.

Animals↗
PubMed1975

Incidence of Listeria monocytogenes in nature.

During a research project on the occurrence of Listeria monocytogenes 194 strains were isolated in southern West Germany during the years 1972 to 1974:154 from soil and plant samples (20.3%), 16 from feces of deer and stag (15.7%), 9 from old moldy fodder and wildlife feeding grounds (27.2%), and 8 from birds (17.3%). The highest number of isolates was obtained from uncultivated fields. The beta-hemolytic serovars 1/2b and 4b were were predominant; other serovars (some of them identified for the first time), including nonhemolyzing strains, have been encountered frequently. It is suggested that Listeria monocytogenes is a saprophytic organism which lives in a plant-soil environment and therefore can be contracted by humans and animals via many possible routes from many sources.

Animal Feed↗