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Biomedical subjects

H Pothe

Publications and source records attributed to H Pothe.

At least 19 recordsLinked to original sources

[Preoperative computer tomography and postoperative classification of brain tumors].

Imaging of different brain tumor types by computed tomography (CT) or contrast-enhanced CT scans is often very similar. Therefore, the exact preoperative CT diagnosis of intracranial neoplasms is difficult. Among 100 cases (88 primary brain tumors, 12 brain metastases), the preoperative classification by CT was correct in 51 and partially correct in 22 cases. A corresponding presumptive CT diagnosis was made in 22 brain neoplasms. 5 cases were misinterpreted. Examples of CT scans and histological pictures are compared and analysed according to the literature.

Brain Neoplasms

[Possible diagnostic misinterpretations in chronic epidural hematoma].

Of fifteen epidural hematomas with a protracted course of growth, three were preoperatively diagnosed on the suspicion of tumorous growth. By taking into account the entire course of disease, evidence of posttraumatic complications was obtained only from anamneses and, in one single case, from a fracture of the skull. Using the methods of instrumental neuroradiological diagnosis, the intracranial occupation of space could not be observed to be outside of the cerebrum.

Adult

[Problems in the treatment of fronto-basal fractures].

Midfacial fractures are frequently combined with frontobasal fractures. For this reason, it is important to the oral surgeon to be knowlegeable of the basic principles of the treatment of frontobasal fractures. The rule of general surgery that any open injury should be transformed into a closed one, also applies to these fractures. The indication for operation and the time of operation depend upon the kind of lesion. The intradural closure of the dural is regarded as the method of choice. Details of the operating technique are presented.

Dura Mater

[Operative treatment of frontobasic fractures (author's transl)].

The number of fractures of the scull especially of its fronto-basic portion is steadily increasing. So the general surgeon is more and more confronted with the problem of indication concerning oeprative procedures. He should be trained to take care of these injuries.

Adult

[Splenectomy; its results (author's transl)].

270 patients underwent splenectomy for different indications. The rate of complications amounts to 18,8%. Prognosis after splenectomy depends on the basic disease, accompanying illness and the quality of pre- and postoperative care.

Female

[Clinico-endoscopic problems in malignant changes of the gastric stump].

The authors give a report on occasional difficulties concerning the radiological and endoscopic clarification of the malignant changes at the gastric stump after treatment of resection. Four relevant cases are stated and explained. The endoscopy (glass fibre gastroscopy) together with the biopsy is at present the most reliable method for the diagnosis of the pathological processes in the remaining part of the stomach. A regular endoscopic and radiological control of patients with gastric resection is desirable.

Female

[The primary gallbladder neoplasm].

From 1960 to 1975 in the Surgical Clinic of the Medical Academy Erfurt altogether 77 patients with a primary malignoma of the gall-bladder were observed. Symptomatology and findings are non-characteristic. 64 times a laparotomy was carried out, whereby in 51 cases the intervention had to be finished as test laparotomy. 13 times a cholecystectomy or a biliodigestive anastomosis was carried out. The average survival time of the patients with test laparotomy was 53 days. A survival time of more than one year could nertainty. Issuing from this the author adopts a definite attitude to carcinogenesis and the importance of lithiasis.

Alkaline Phosphatase

[Relationship between patient delay and prognosis in gastric cancer in an unselected population (author's transl)].

Whereas the morphology of malignant neoplastia is well known, exact information on the natural history of cancer is lacking. Some hints in this direction can be gained from detailed observations of the course of disease and from correlations between duration of history and prognosis. In the literature, views on the dependence of prognosis on duration of delay are conflicting. This was the reason why we examined this relationship in gastric cancer in the region of Erfurt, GDR, based on the unselected data of the cancer registry. 1838 cases of gastric cancer in male in 1960--1969 could be evaluated concerning prognosis and patient delay. In 2575 cases, relationship between duration of delay and clinical stage as well as mode of treatment could be investigated. From the statistical evaluation it was concluded that a long history is a sign of a less aggressive tumour growth. A short delay seems to be an index of adverse host-tumour relations. Better treatment results can be expected by shortening of patient delay. Possibilities to change the situation are discussed. A more centralized organisation of surgical care is proposed.

Germany, East

[Prognosis of colonic and rectal cancer under selection free conditions (author's transl)].

Incidence of cancer of colon and rectum shows increasing tendency in G.D.R. It is necessary to orientate practical medicine in this direction respecting future needs in scientific and therapeutic view. Published results of treatment deceive in true prognosis, because they are commonly from special hospitals. Effects of selection, lack of uniform definitions and faults in statistics may lead to unfounded optimism. Reports on treatment results which are free from selection bies are rare till now. The National Cancer Registry in the Erfurt Region gave crude absolute five-year-survival rates of 10.3% in colonic cancer and 10.8% in rectal cancer for the years 1960-1966. Radical operations resulted in survival rates of 26.4% and 27.4%. The author draws conclusions concerning education of general practitioners, improvement of diagnostic facilities, and centralized organization of special medical care for cancer patients.

Age Factors

[Results of treatment of stomach cancer in a closed population free of selection bias (author's transl)].

Treatment results of surgery for gastric cancer differ widely in contemporary reports. This depends on criteria of selection and on composition of patients. Only results of treatment without any selection can give a solid ground for rational planning of cancer control measures. It must be admitted that there is a need for information concerning regional results of treatment of gastric cancer for planning of control measures. An investigation in the district of Erfurt, German Democratic Republic, gave some interesting data: The crude absolute 5-year survival rate for all stomach cancer cases in males registered in 1960-1966 reached 4,7% (87 of 1838). Distal partial gastrectomy gave 68 of 372 (or 18,3%) 5-year survivors. After radical total gastrectomy 8,6% (7 of 81) survived 5 years or more. In the first year following treatment, 81% (1488 of 1838) were registered as dead. Survival rates depend on age: 5 years survival rate of patients up to 65 years was 8,1% (59 of 729) and fell drastically in patients of 65+ years (28 of 1109 = 2,5%). The author gives some recommendations for the development of cancer control in the G.D.R.

Aged