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Biomedical subjects

H R Gordon

Publications and source records attributed to H R Gordon.

6 recordsLinked to original sources

Obstetrical judgments of viability and perinatal survival of extremely low birthweight infants.

OBJECTIVES: The purpose of the study was to determine whether the obstetrical judgment of viability makes a difference to fetal and neonatal survival of extremely low birthweight infants (500-749 g). METHODS: We assessed the effect of the antenatal judgment of viability in a group of 66 infants born weighing from 500 to 749 g. These infants were alive at maternal hospital admission and were subsequently live-born or stillborn between January 1, 1984, and December 31, 1985. We related the antepartum assessment of viability and other factors recorded in the medical record to fetal survival and to postneonatal survival to hospital discharge. RESULTS: The obstetrical judgement of viability was strongly associated with outcome. After birthweight and gestational age were controlled, fetuses considered viable were 18 times more likely to survive (95% confidence interval = 2, 175) than those considered nonviable. CONCLUSIONS: The effects of obstetrical practices on perinatal mortality must be taken into consideration in estimating the survival potential of very small fetuses and in evaluating the relationship between survival and disability.

Apgar Score↗

Prophylactic cesarean section antibiotics: maternal and neonatal morbidity before or after cord clamping.

In an ongoing prospective study at 2 hospitals, 114 cesarean section patients were studied to determine whether giving ampicillin after umbilical cord clamping is as effective as perioperative ampicillin in reducing maternal postoperative morbidity. The same patients have also been studied to determine the effect of prophylactic cesarean section ampicillin on the newborn. Results have shown that prophylactic ampicillin initiated after cord clamping is as effective in reducing maternal morbidity as ampicillin initiated prior to the surgery. There is also no evidence from our study that the transplacental passage of prophylactic ampicillin increases immediate or delayed neonatal infections.

Ampicillin↗

Suprapubic vs. periumbilical amniocentesis.

Amniocentesis has assumed a major and increasing role in the proper management of highrisk pregnancies but the procedure is not without complications. This study was undertaken to compare the suprapubic with the periumblical or "small-parts"approach. A total of 308 amniocenteses were included. The suprapubic method had fewer failures and fewer complications. The rate of premature rupture of the membranes was identifical with both approaches; in fact, following either type of amniocentesis, the percentage of premature ruptured membranes was no differnet from the anticipated spontaneous rate. In all cases of premature rupture of the membranes there were no cases of respiratory distress syndrome, maternal infection, or neonatal infection.

Amniocentesis↗