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Suprapubic vs. periumbilical amniocentesis.

H R Gordon·A G Deukmedjian
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Abstract

Amniocentesis has assumed a major and increasing role in the proper management of highrisk pregnancies but the procedure is not without complications. This study was undertaken to compare the suprapubic with the periumblical or "small-parts"approach. A total of 308 amniocenteses were included. The suprapubic method had fewer failures and fewer complications. The rate of premature rupture of the membranes was identifical with both approaches; in fact, following either type of amniocentesis, the percentage of premature ruptured membranes was no differnet from the anticipated spontaneous rate. In all cases of premature rupture of the membranes there were no cases of respiratory distress syndrome, maternal infection, or neonatal infection.

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AmniocentesisApgar ScoreCesarean SectionDelivery, ObstetricFemaleFetal DistressPremature Rupture of Fetal MembranesHumansMeconiumPregnancyPubic BoneUmbilicusVaginaComparative StudyJournal Article

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H R Gordon, A G Deukmedjian. 1975-06-01. Suprapubic vs. periumbilical amniocentesis.. https://doi.org/10.1016/0002-9378(75)90169-6

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Amniocentesis for twin pregnancies: is alpha-fetoprotein useful in confirming that the two sacs were sampled?

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PubMed2007

Fetal anomaly scan potentially will replace routine AFAFP assays for the detection of neural tube defects.

OBJECTIVES: Introduction of the second-trimester fetal anomaly scan and the decision to offer this scan to every woman in the 18th-22nd week of pregnancy necessitates a re-evaluation of the diagnostic value of the measurement of alpha-fetoprotein (AFP) concentrations in the amniotic fluid (AF) for the detection of neural tube defects (NTDs). METHODS: In this study of 6501 women who underwent amniocentesis, amniotic fluid AFP (AFAFP) concentrations were measured. The women were divided into three categories: group I, without any increased risk of fetal NTD (N = 6188); group II, with an increased risk of fetal NTD (N = 258); and group III, with a clinically diagnosed fetal NTD with known AFAFP concentrations (N = 55). RESULTS: In 27 women of group I (0.4%), the MoM (multiple of the median) level was > 2.5 times the median AFP concentration for the corresponding gestational age, and in two fetuses this was related to NTD. In two pregnancies of group II (0.8%), an increased AFAFP was related to NTD. In group III, 44 of the 55 (80%) samples had an increased AFAFP. CONCLUSION: In the near future, it is likely that imaging will replace AFAFP assays for the detection of fetal NTDs because high quality ultrasound imaging will detect NTDs accurately.

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