Biomedical subjects

H Stanulla

Publications and source records attributed to H Stanulla.

At least 37 records · Page 2Linked to original sources

PubMed1977

[Statement of the bioptic diagnostic in intrathoracic sarcoidosis--team work of 6 lung hospitals of the GDR (author's transl)].

A nearly nation-wide team-work of six chest hospitals was made with 4284 patients to analyse all performed diagnostic procedures up to the present. Its frequency and diagnostic importance in relation to the radiographic stages of the disease were examined. Especially the procedure of bronchologic examination, having been partly underrated with the morphological ascertainment of sarcoidosis, are now purposefully analysed. This showed that also with perbronchic punction-biopsy and bronchoscopic excision morphologically confirming of the diagnosis was possible at a high percentage. On the other side the right diagnosis was made clinically before bioptic procedures in the majority of the patients. The overall conclusion is that, according to the experiences made in our hospitals, the relatively harmless bronchologic procedures are in general sufficient to obtain bioptic verfication of the diagnosis "sarcoidosis". Other bioptic operations like mediastinoscopy or lung biopsy can be restricted to cases with reasonable doube of the diagnosis.

Biopsy, Needle↗

PubMed1977

[The prognosis of intrathoracic sarcoidosis on the basis of the clinical picture and the histological feature in the mediastinal lymph nodes (author's transl)].

The clinical course of (pulmonary) sarcoidosis is difficultly foreseeable with regard to the fate of a given patient. There are some clinical features to get a probably good or probably poor prognosis, but there are only a few presumptions about the correlation between the histologic patterns with the clinical course. Lymph nodes were removed by mediastinoscopy. The authors have the intention with the aid of the histologic picture in these lymph nodes to examine, if 1. micro-cellular reactions and pure epithelioid-cell granulomas may have a better prognosis than 2. central necrosis, hyalinization, and fibrosis, whereas 3. the number of giant cells seems to be without prognostic significance.

Chronic Disease↗

PubMed1977

[Atrial myxomas of the heart; diagnosis, therapy and morphology (author's transl)].

Atrial myxomas imitate several other clinical entities. The intravital diagnosis may still appear as a surprise. Myxomas can present themselves in 2 ways: by obstruction of intracardiac blood flow and by embolization. Early diagnosis should be established by utilizing angiography. Immediate resection under total cardiopulmonary bypass should be performed before catastrophic complications occur.

Adult↗

PubMed1976

[Pulmonary glomangiosis (author's transl)].

The clinical aspects, differential diagnosis and aetiology of the rare pulmonary glomangiosis are described by means of four cases observed in our clinic. It is a hamartogenous stenosing disease of the lungvessels, appearing predominately in children who suffer from congenital heart disease. It leads to pulmonary hypertension. The pulmonary glomangiosis is of practical importance: By palliative operation as the banding of the pulmonary artery the demand hypertension in the pulmonary circulation is suppressed artificially, so that in heavy cases a sufficient oxygenation is not provided, and the children die in the postoperative period. From the surgical aspect such a disease of the pulmonary vessels has to be supposed when the blood pressure distally of the experimentally banded pulmonary artery drops insufficiently. The authors recommend to exclude the disease of the vessels by excicion of lungtissue and immediate histologic investigation before the final banding is performed.

Child↗

PubMed1976

[The problem of sirenoid malformation].

The pathological-anatomical and radiological findings of the rare sirenoid malformations which have to be assigned to the disturbed developments of the candal vertebral column section are discussed taking a female apodal sirenomelus involving agenesia of a large part of the intestine and the urogenital tract. About 330 cases have been dealt with in international publications. Exogenic factors are in the foreground, mainly hypoxemic conditions during the embryogenesis whereas heritability is apparently not given.

Abnormalities, Multiple↗

PubMed1976

[Mediastinoscopy--indications, efficiency, and morphologic findings in more than 2250 investigations (author's transl)].

2276 diagnostic mediastinoscopies were performed and their efficiency was analysed. Except from patients with bronchial carcinomas, in 80% of all cases pathologic findings with diagnostic significance could be found in the lymph-nodes. CARLENS mediastinoscopy proved to be less efficient in the prognostic evaluation of bronchial carcinomas. In 521 patients with bronchial carcinomas only 146 (28%) showed mediastinal lymph-node metastasis detected by mediastinoscopy. But in the remaining 375 cases the operation revealed in 51.5% the occurence of perihilar metastatic lymph-nodes. The most important morphological findings in lymph-nodes and their differentialdiagnostical problems are discussed with reference to sarcoidosis, sarcoid-like reaction, tuberculosis, and silicosis.

Biopsy↗

PubMed1975

[Plastic closure of a bladder wall defect by use of a pedicled auto-alloplastic prosthesis in experiments].

The problems of substituting larger areas of the bladder wall are not definitely solved. Experiments on implantation of auto-allografts resulted in complications, which prevented correct epithelization of the interior surface, due to ischemia. In successful experiments on 34 rabbits, the authors obtained sufficient blood supply of the implantate and re-epithelization of the graft's interior surface in a two-stage operation.

Animals↗

PubMed1975

[Pneumopathia osteoplastica (pulmonary ossification) (author's transl)].

The Pneumopathia osteoplastica is a rare disease manifesting in two different forms of appearance. The tuberous (nodular) ossification affects mainly younger persons and is resulting in the great majority from chronic congestion of the lung due to mitral stenosis. Compared to it the idiopathic racemose (ramified) form affects older males. The paper is based on 9 cases of the two morphologic variants. The clinical aspects, etiologym morphology, and differential diagnosis of them are discussed with regard to newer publications.

Adult↗

PubMed1974