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Biomedical subjects

H Vander Eecken

Publications and source records attributed to H Vander Eecken.

At least 19 recordsLinked to original sources
PubMed1990

[Neuropsychological observations and clinical neurology].

The term "neuropsychology" covers the study of the higher functions of man with respect to the structure and the functional organisation of the nervous system, and therefore clearly belongs to the neurological sciences. The nervous system forms a whole, composed of innumerable integrating mechanisms, ordered into a hierarchy of levels ranging from the most elementary activities, which are the most genetically determined and the most permanent, to the activities that are predominantly acquired, which are the most mobile and the most reversible ones. All parts of the nervous system--ranging from the simplest to the most complex--contain reflecting cycles, which maintain themselves in relationships of mutual dependence. The impairment of one or other activity does not mean that the function resides in the damaged part of the nervous system, but merely implies that this part is essential for its completion. The perception of an agnosia patient, the locomotor system in the case of disturbed apraxia, the reactions of a patient with disturbances in the state of consciousness, the mental capacities of a demented person, all these are the result of the global activity of a nervous system which has been depleted of certain capacities and which is curbed by new limitations. In the infinite tangle of the cerebral system, the lesion cancels one or more links which fulfil a physiological role. Depending on where the broken link is situated, the remaining functional organisation coming to the surface in this way expresses itself in a pattern of behaviour which is not strictly related. According to the principle introduced by Jackson, the lesion eliminates certain activities, and releases others, which integrate themselves into underlying levels. In this way the activities of the nervous system regress according to the opposite direction of the hierarchic evolution of their structure: from the most complex to the simplest, from the most propositional to the most automatic, from the least to the most organised.(ABSTRACT TRUNCATED AT 400 WORDS)

Aging↗
PubMed1985

Acid phosphatase activity of cerebrospinal fluid cells in leptomeningeal haemorrhage.

One hundred and twenty samples of haemorrhagic spinal fluid were examined by acid phosphatase staining. This enzyme activity starts to appear in mono-histiocytic cells 2 days after bleeding and increases up to the 5th day. After 1 week the activity decreases rapidly. Similar results are found in mixtures of incubated clear spinal fluid, to which blood is added. Acid phosphatase staining is a useful additional method for determination of the age of a leptomeningeal bleed.

Acid Phosphatase↗
PubMed1984

The use of semiautomatic morphometry in the study of normal rat gastrocnemius muscle fibers.

Based on a fixed number of EM photomicrographs, a semiautomatic image analysis is made of normal gastrocnemius muscle fibers to obtain reference values for comparison with pathologic data. Z disc, mitochondria, tubular system, and sarcoplasmic reticulum are measured. It is stated that no definite fiber type differentiation is possible based on these quantitative data. However, measurements of Z disc and mitochondria are suggestive of such a differentiation. On the other hand, all data reach a Gaussian distribution on a logarithmic scale after a 5% correction factor is introduced.

Animals↗
PubMed1983

Influence of stretch on the target phenomenon in the tenotomized and immobilized gastrocnemius muscle of the rat.

The influence of traction on the target phenomenon was analysed in the tenotomized gastrocnemius muscle of Wistar rats. Target fibres were constantly observed at the medial side of the heads of the non-immobilized and tenotomized gastrocnemius muscles used as control. In the muscles fixed in flexion, no target fibres could be detected, while in the muscles fixed in hyperextension some target fibres were seen. The latter were less numerous than those present in the non-immobilized muscles. This experiment proves the importance of stretch mechanisms in the pathogenesis of the target phenomenon.

Achilles Tendon↗
PubMed1983

Brain maturation and types of perinatal hypoxic-ischemic encephalopathy.

The degree of brain maturation and the location of hemorrhage in the germinal layer and of periventricular leukomalacia were analyzed in 85 newborn brains. The average age of the premature brains with hemorrhage was 31 weeks and of those with leukomalacia 37 weeks. Hemorrhage was more frequently found in the frontal regions, while periventricular leukomalacia predominated in the parieto-occipital regions. This study confirms that the type and the location of the hypoxic-ischemic perinatal cerebral damage are dependent on the rate of regression of the embryonic type of periventricular arterial vascularization in the premature brain.

Brain↗
PubMed1982

Migraine-like headache in intraventricular tumours.

In a series of 39 intraventricular tumours, 7 patients had paroxysmal headache as the most important early complaint. The striking similarities with migraine and the misleading role of antimigraine drug therapy are illustrated. Special emphasis is placed on the importance of additional investigations such as funduscopy, EEG, skin X-rays and Ct-scan.

Cerebral Ventricle Neoplasms↗
PubMed1981

Prospective neuropathologic study on the occurrence of Wernicke's encephalopathy in patients with tumours of the lymphoid-hemopoietic systems.

In this prospective neuropathologic study, Wernicke's encephalopathy appears to be the most frequent intracranial complication of treated patients with tumours of the lymphoid-hemopoietic systems. The highest incidence of this encephalopathy is found in elderly and in patients with a prolonged survival. The chronic form of Wernicke's encephalopathy is most commonly observed.

Adolescent↗
PubMed1980

[Pathophysiology of tetanus rigidity (author's transl)].

Brainstem reflexes have been studied electrophysiologically in six patients with generalized tetanus. The selective impairment of reflexes with long polysynaptic pathways supports the assumption of an interneuronal dysfunction in tetanus. The behaviour of proprioceptive reflexes suggests that hyperactivity of gamma-motoneurons contributes to the rigidity in an early stage of the disease.

Adult↗
PubMed1979

Cytophotometric DNA determination in human astroglial tumours.

The DNA content is determined by the cytophotometric method in 16 astroglial tumours, classified according to the degree of clinical malignancy. The values are compared to those found in non-tumoural astrocytes. This method appears to be more reliable in assessment of the degree of malignancy of the tumour in biopsy material than histological criteria and the mitotic index. It is also shown to be of great value in cases where the biopsy is taken at the margin of the tumour and in which malignant histological features are missing.

Adolescent↗
PubMed1979

Comparative study of the clinical effect of vincamine versus papaverine given parenterally in the acute phase of stroke.

The efficacy of the "oxygenator", vincamine was assessed in comparison to a classic vasodilator, papaverine, after parenteral administration during the first days of an acute thrombo-embolic stroke. All 263 patients admitted to this open trial had a thrombo-embolism of the A. carotis or one of its cerebral branches within the previous 24 h. Patients demonstrating minimal neurological deficit or requiring admission to an intensive care unit, or patients with a suspected hemorrhagic syndrome were excluded. Each patient received i.v. infusions (15 mg X 6) of 6 vials of vincamine per 24 h, or 6 vials of papaverine (40 mg X 6) per 24 h, occasionally in combination with acetylsalicylic acid (ASA), dipyridamol and hydrocortisone. An initial 3-h control was followed by regular surveillance for 5 days, paying special regard to consciousness and motricity. The administration of vincamine alone had a significantly more favourable effect than papaverine alone on consciousness (p less than 0.001). Furthermore, vincamine associated with other drugs was significantly superior (p less than 0.01) to papaverine given in association. A similar tendency was noted for motor recuperation after vincamine compared to papaverine (p less than 0.001). Vincamine and papaverine were well tolerated during the 5-days observation period, only one side effect after vincamine and four after papaverine being noted.

Adult↗
PubMed1976

The target phenomenon in human muscle: a comparative light microscopic histochemical and electron microscopic study.

A large number of target fibres is observed in a muscle biopsy from a patient with an acute flaccid paraplegia of the lower limbs due to a polyneuroradiculopathy of unknown origin. With the electron microscope up to 4 structural zones are seen in the target fibers. The histochemical and ultrastructural observations in this case, suggest that the "target fiber" phenomenon is due to a disturbed trophic influence of the nervous system.

Female↗
PubMed1976

Biometrical and histochemical comparison between extra- and intrafusal muscle fibres following tenotomy.

The average diameter of the different enzymatic types of extra- and intrafusal muscle fibres is determined by means of a one millimeter scale ocular micrometer in the gastrocnemius muscle of twenty four female rats during three months, at regular intervals following tenotomy. There is a predominant atrophy of the type II extrafusal as well as intrafusal fibres in the period of immobilization. However, when the muscle becomes functional again, by healing and elongation of the tendon, the intrafusal type II fibres remain atrophic in contrast to the extrafusal ones, which regain their normal size.

Achilles Tendon↗