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Biomedical subjects

H Vander Eecken

Publications and source records attributed to H Vander Eecken.

At least 37 records · Page 2Linked to original sources

Biometrical and histochemical comparison between extra- and intrafusal muscle fibres following tenotomy.

The average diameter of the different enzymatic types of extra- and intrafusal muscle fibres is determined by means of a one millimeter scale ocular micrometer in the gastrocnemius muscle of twenty four female rats during three months, at regular intervals following tenotomy. There is a predominant atrophy of the type II extrafusal as well as intrafusal fibres in the period of immobilization. However, when the muscle becomes functional again, by healing and elongation of the tendon, the intrafusal type II fibres remain atrophic in contrast to the extrafusal ones, which regain their normal size.

Achilles Tendon↗

Paralytic pontine exotropia in subarachnoid hemorrhage. A clinicopathological correlation.

A syndrome of combined right lateral gaze palsy and right internuclear ophthalmoplegia, followed by a left exotropia in a case of subarachnoid hemorrhage is presented. At necropsy a single small pontine end-zone infarction was found, involving the medial part of the right paramedian pontine reticular formation, the tectospinal tract and the ventral part of the right medial longitudinal fasciculus. The fila radicularia of the right abducens nerve passed through the necrotic area. The mechanism of these characteristic ocular motor disturbances in relation to the post mortem findings and the topopathogenesis of the pontine infarction are discussed.

Female↗

The pseudo-rhythmic electroendephalogram after cardiac arrest.

Five cases are presented showing on the EEG pseudo-rhythmic discharges appearing on almost flat lines, after reanimation of a cardiac arrest. The morphology of the complexes is quite similar, except in the period immediately preceding death, where they are more disformed. All patients died within the following days, except one. In four of the five cases myoclonic jerks occurred, consisting of brief convulsions over the whole body, especially in the arms and the face. A literature survey shows that this EEG pattern after circulatory arrest, is not rare. It is almost always followed by death. Myoclonic jerks may or may not be present and are not necessarily synchronous with the EEG discharges. The electrogenetic origin is not yet elucidated, although it seems that the pattern may appear at a state of complete loss of cortical function.

Adult↗

Early ultrastructural changes in aging rat gastrocnemius muscle: a stereologic study.

Normal gastrocnemius muscle of Wistar rats at various ages to 2 1/2 years was studied. No light microscopic or qualitative electron microscopic changes were seen. However, stereologic determinations revealed significant reductions in volume and surface densities of sarcoplasmic reticulum, t-tubular system, and glycogen content. These alterations were considered to be the morphologic expression of the very early age-related changes in gastrocnemius muscle.

Aging↗

The Elizur test of psycho-organicity (adults). A cross-validation study.

In an effort to cross-validate the Elizur Test of Psycho-Organicity (performed on adults), a combined test used for the diagnosis of organic brain condition, 96 subjects were tested. The test can differentiate the "organic" and "non-organic" groups in a statistically significant manner. Eighty-five percent of the organics and 81% of the non-organics can be correctly identified by the test. In addition there is a significant correlation between the test findings and the electroencephalographic and radiographic results.

Adult↗

Central pontine myelinolysis and its arterial blood supply.

A case of central pontine myelinolysis is described. The clinical, angiographic and post mortem findings suggest that among the associated disorders the oligemic shock combined with a local decreased flow in the basilar artery was the most important cause of this patholigical entity. The angioarchitecture findings in the brain stem, compared to these in 26 normal brains, confirm this hypothesis.

Alcoholism↗

Cerebrospinal fluid cytology in acute ischaemic stroke.

Quantitative and/or qualitative changes in cerebrospinal fluid (CSF) cytology were observed in 31.5% of 225 samples, obtained from patients with recent non-haemorrhagic cerebral infarctions. These changes were variable and did not correlate with the stroke pattern or with the topography of the softening. The CSF cytological abnormalities were statistically different according to the aetiology of the stroke. In those infarctions, due to vasculitis lesions, either of infectious or of auto-immune nature, an abnormal cytology pattern was more frequently observed than in those of atherosclerotic thrombo-embolic origin.

Acute Disease↗

Subarachnoid hematoma in staphylococcal septicemia. A report of two cases.

Two cases of subarachnoid hematoma, due to a Staphylococcus aureus septicemia are described. The clinical as well as the pathological findings suggest a two-step evolution, consisting first in the appearance of a small to moderate stroke, due to a septic embolic occlusion of a leptomeningeal artery and to cerebral infarction, followed by rupture of the artery and the formation of the subarachnoid hematoma, acting as a mass-lesion and leading to death by uncal herniation and brain stem compression. The typical location of the hematoma over the convex surface of a cerebral hemisphere suggests that local factors, such as the vicinity of patent leptomeningeal anastomoses and the fibrosis of the leptomeninges, are probably predisposing factors for its occurrence.

Aged↗

Radicular lesions in tuberculous meningitis. A clinicopathological study.

In the present work, the involvement of cranial and spinal nerve roots in tuberculous meningitis was studied. Cranial nerves of 11 cases and the spinal roots of three patients were examined by means of serial sections of the base of the brain, brainstem and spinal cord. Although entrapment of the nerves by the tenacious inflammatory exudate was prominent, vasculitis lesions of the cranial nerves and spinal roots were also frequently observed. The latter could be an additional cause of nerve palsies in tuberculous meningitis.

Adult↗

Cerebellar infarction and internal hydrocephalus.

Four cases of acute cerebellar infarction producing hydrocephalus are presented. Only the patient, who is submitted to surgical decompression of the posterior fossa, survives, while the other three die. In the latter the necropsy shows a hemorrhagic cerebellar softening in the territory of the inferior posterior cerebellar artery, causing tonsillar herniation and impairment of the liquor drainage at the level of the inferior part of the 4th ventricle. It is suggested that the infarction and the hydrocephalus further progress in "avalanche effect", which is fatal unless prompt surgical decompression can be carried out.

Aged↗