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Biomedical subjects

H W Ocklitz

Publications and source records attributed to H W Ocklitz.

At least 19 recordsLinked to original sources
PubMed1989

[The clinico-diagnostic value of C-reactive protein, determined by simple radial immunodiffusion and compared with latex agglutination].

Importance of CRP-determination in rapid diagnosis of septic diseases in children is being examined. Specificity and sensitivity of white blood cell count, thrombocyte count, blood sedimentation rate, differential blood count and CRP were evaluated statistically. Rapid diagnosis was performed with sera of 95 patients shortly after being admitted on ward. The values of children with serious bacterial diseases were compared with those of children with serious abacterial ones. Significant superiority of CRP was established. To be successful a rapid and simple method must be available. In our study combined measurement of CRP by latex agglutination and RID has turned out to be advantageous for early detection of bacterial infection.

Bacterial Infections↗
PubMed1983

[Trends in infectious diseases].

Infectious diseases can be comprehensively divided in 4 groups by means of the parameters morbidity and lethality. This enables us to describe the continuously changing epidemiologic situation till the present state in this country in a simple way. New essential trends in etiology and pathogenesis are outlined, followed by a few selected therapeutical and prophylactic aspects. Finally problems of intrauterine acquired and neonatal infections are discussed.

Bacterial Infections↗
PubMed1980

[The protective effect of an EDTA-sodium-extract-vaccine obtained from swine-pathogenic E. coli in a field trial. 1. Communication: Direct and indirect immunization of suckling piglets (author's transl)].

Pentavalent EDTA-Sodium-extract-vaccines and monovalent EDTA-Sodium-extract-vaccines obtained from swine-pathogenic E. coli and produced in Berlin-Buch were used in field trials to test their antiepizootic effect in industrial pig-farms in the district of Wrocław. The pentavalent vaccine contained extracts from E. coli O138, O139, O141, O147, and O149, whereas extracts from O8, O115 and O149 were used as monovalent vaccines. The field trials were conducted as blind trials is closed stocks of pigs. We employed direct oral immunization of suckling piglets and indirect immunization via sow vaccination. Direct oral immunization was tested in 382 suckling piglets. 190 animals were vaccinated, 192 animals received placebo. Neither the pentavalent vaccine nor a monovalent vaccine obtained from an epizootie strain of this stock gave protection in terms of a decrease in the duration of disease or a reduction of morbidity and mortality. Direct oral-immunization of suckling piglets thus was ineffective. Indirect immunization of the suckling piglets via vaccination of sow was performed in 189 pregnant sows 18--15 days before farrowing. 84 sows received vaccines i.m., 105 were given placebo i.m. These sows farrowed 1717 pigs, 777 of which were immunized indirectly and 940 treated with placebos. With the pentavalent vaccine and with the monovalent vaccine obtained from an epizootic strain we achieved significant protection of the indirect vaccinated suckling piglets.

Administration, Oral↗
PubMed1980

[The protective effect of an EDTA-sodium-extract-vaccine obtained from swine-pathogenic E. coli in a field trial. 2. Communication: Immunization of weanling piglets (author's transl)].

Pentavalent EDTA-Sodium-extract vaccines and monovalent EDTA-Sodium-extract vaccines obtained from swine-pathogenic E. coli were used to test their antiepizootic effect in industrial pig farms, 2929 piglets after weaning were included in this field trial, 1309 were immunized partly orally, partly i.m., 1620 piglets received placebos accordingly. By means of oral immunization the pentavalent vaccine was capable of reducing the morbidity of the vaccinated animals significantly. Intramuscular immunization with the pentavalent vaccines produced significant differences in morbidity too. A monovalent vaccine obtained from E. coli O149 and E. coli O8 was shown to be equally effective, whereas a monovalent vaccine obtained from E. coli O115 was ineffective. But in this stock there were infections with O149 but none with O115 or O8.

Administration, Oral↗