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Biomedical subjects

H Yildiz

Publications and source records attributed to H Yildiz.

3 recordsLinked to original sources

Composite hip prosthesis design. II. Simulation.

An investigation was performed to study the mechanical performance of fiber-reinforced composite hip prostheses. In Part I of the study, a three-dimensional finite element code was developed for analyzing a composite hip prosthesis in a femur. The material properties of the composite were treated as anisotropic and inhomogeneous while the properties of the femoral bone were treated as anisotropic and homogeneous. All the materials were assumed to behave linear-elastically. Thermoplastic graphite/PEEK material was selected for the study. No slippage was assumed at the interface between the implant and the surrounding femoral bone. In Part II, numerical simulations were performed using the code to study the performance of a composite prosthesis in the femur. The stress/strain distributions, micromotions, and strain energy density of the surrounding femoral bone were evaluated and found to be related to initial fixation and long-term stability of the prosthesis in the femur. Numerous fiber orientations were studied, and the results of the calculations were compared with those generated from a prosthesis made of cobalt chrome and Ti-6Al-4V titanium alloys. Based on the analysis, it was shown that compared to conventional metallic implants more favorable stresses and deformations could be generated in the femur using composite implants. In addition, by changing fiber orientations according to femoral loads, a composite implant could be designed specifically for the left or the right femur.

Computer Simulation

Composite hip prosthesis design. I. Analysis.

An investigation was performed to study the mechanical performance of fiber-reinforced composite hip prostheses in a femur. The main objective of the study was to evaluate the effect of fiber orientation of a composite femoral implant on the response of the surrounding femoral bone. A three-dimensional finite element analysis was developed for analyzing a composite implant in the femur. A three-dimensional composite element was proposed to take into account ply drop-off due to a change of cross-section of the composite implant. The element could accommodate multidirectional layers and tapered composites. The material properties of the composite were treated as anisotropic and inhomogeneous while the properties of femoral bone were treated as anisotropic and homogenous. All the materials were assumed to behave linear-elastically. The thermoplastic graphite/PEEK material system was selected for the study. In this presentation, as the first part of the study, the development of the finite element analysis will be described. Numerical calculations were generated and compared with existing data and numerical results available from studies related to metal hip prostheses in the literature. Experiments on the composite hip implants were also conducted for further verification of the analysis and the computer simulations. In Part II, using the finite element code, an extensive study was performed to evaluate the stress/strain distributions, micromotions, and strain-energy density of the surrounding femoral bone, which have been related to initial fixation and long-term stability of the prosthesis in a femoral bone. Numerous fiber orientations were studied, and results of the calculations were compared with those generated by the prosthesis made of cobalt alloy and titanium alloy.

Hip Prosthesis

An investigation on plasma progesterone levels during pregnancy and at parturition in the Ivesi sheep.

In this study, plasma progesterone concentrations in a total of 45 Ivesi sheep were investigated during pregnancy and at parturition. Blood samples were collected from all the sheep studied every 20 days commencing on the 30th day of pregnancy. Plasma progesterone levels were determined by radioimmunoassay. During the second half of the pregnancy, progesterone concentrations in the sheep giving birth to one, two and three lambs were 2.02 +/- 0.08 ng/ml, 3.24 +/- 1.18 ng/ml and 4.90 +/- 0.85 ng/ml, respectively. There was no significant variation in progesterone levels between sheep with male and female offspring. At parturition, plasma progesterone concentrations did not differ significantly between the animals. The present results indicate that plasma progesterone levels could be used not only to determine the pregnancy status of the animal but also to predict the number of fetuses after the second half of the pregnancy.

Animals