[Standardized intravenous phenolred test].
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Biomedical subjects
Publications and source records attributed to H Zöllner.
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Intravenous application of 1 mg glucagon causes a significant decrease of the magnesium, calcium, and phosphate concentrations in the serum. Concerning the potassium level there is a biphasic change of concentration. Initially a significant increase of the potassium concentration is to be measured which transgresses into a longer phase of decrease of concentration. The possible causes of these changes of electrolytes after application of glucagon are discussed and it is referred to the possible clinical importance. In longer therapeutic application of glucagon a control of the serum parameters of the electrolytes metabolism appears indicated.
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In non-renal (diabetic) glucosuria we did not find any statistically real relations between the concentration of glucose in the urine and cryoscopically measured osmolality in children with healthy kidneys. The close negative correlation of the conductance of the urine to the concentration of glucose is not only to be explained by changes of the viscosity, but is an expression of an increased re-absorption of sodium as a result of a compensatory hyperaldosteronism. In renal insufficiency the electrolytic conductibility of the urine is lower than the borderline area of the normal, even when under influence of the glucose excretion the osmolality of the urine is still to be found normal. Thus also on the conditions of a considerable glucosuria we can further judge the concentrating ability of the kidney in diabetes mellitus with the help of the measurement of the conductance of the urine.
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