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Hsieh-Ting Wu

Publications and source records attributed to Hsieh-Ting Wu.

2 recordsLinked to original sources
PubMed2003

Optical heterodyne surface-plasmon resonance biosensor.

A novel optical heterodyne surface-plasmon resonance (SPR) biosensor with a Zeeman laser is proposed. Two surface plasma waves are excited by two correlated p-polarized waves in a SPR device of the Kretschmann configuration. Two reflected p waves are optically heterodyned such that the magnitude of the heterodyned signal is proportional to the multiplication of two attenuated reflected p waves. Then the detection sensitivity and the dynamic range based on this amplitude-sensitive method are enhanced. In the experiment, the kinetics between mouse immunoglobulin G (IgG) and rabbit antimouse IgG is obtained from sensograms of various concentrations of antimouse IgG. A detection sensitivity of 0.2 nM was achieved. In addition, a concentration of 5 ng/ml of protein G interacting with mouse IgG was measured successfully.

Animals↗
PubMed2003

Application of phase-to-amplitude conversion technique to linear birefringence measurements.

A novel technique that measures the linear birefringence of crystal quartz within the configuration of a Soliel-Babinet compensator (SBC) is proposed. A characteristic of this technique is that phase retardation introduced by quartz is amplitude modulation (AM) instead of phase modulation (PM). The linear birefringence is measured regardless of the azimuth angle of the SBC and the orientation of the linear polarization laser beam. Compared with the single-wedge method, the SBC is similar to a parallel plate that allows for a wider range of refracttive index of the test material to be measured. This proposed method uses a conventional amplitude demodulation method in conjunction with an optical heterodyne technique and a bandpass filter to produce a better signal-to-noise ratio. Although the SBC configuration is more complex than a single element, the independence of azimuth angle and the orientation of the linear polarized laser beam can enhance the sensitivity of the linear birefringence measurement.

Journal Article↗