Biomedical subjects
I Blumenthal
Publications and source records attributed to I Blumenthal.
Reflux vomiting.
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The incidence of renal calcification in preterm infants.
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Medical aspects of child sexual abuse.
In the 1980s the extent of child sexual abuse became widely recognized. Most doctors were ill equipped to deal with this 'new' form of abuse. Unlike physical abuse most sexually abused children have no physical signs. The close cooperation between professionals is a legacy of the experience of the last decade.
Ceftazidime in neonatal infections.
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Rectal or axillary temperature in the young child?
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Effects of oral theophylline and oral salbutamol in the treatment of asthma.
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Plasma terbutaline levels in asthma.
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Lymphocytic lymphoma, hypereosinophilia and endomyocardial fibrosis.
A 32-year-old man presented with left hypochondrial pain and myalgia. On examination he was found to have widespread lymphadenopathy and splenomegaly, and lymph node biopsy revealed diffuse lymphocytic lymphoma of the small cleaved cell type. There was hypereosinophilia (20 x 10(9)/1). The patient was initially treated with chlorambucil and prednisone, which controlled the lymphoma for 9 months but did not affect the eosinophilia. He then developed thrombocytopenia with further lymph node enlargement which was managed with a combination of bleomycin, vincristine and prednisone; this again controlled both spleen and lymph node size without affecting the eosinophilia. Six months after presentation the patient developed refractory cardiorespiratory failure due to endomyocardial fibrosis and fibrosing alveolitis. The cardiac failure was thought to be related to the hypereosinophilia resulting from the lymphoma, while the respiratory insufficiency was attributed to the bleomycin. This case illustrates the rare association between lymphocytic lymphoma and eosinophilia and shows that cardiac damage can be associated with these cells.
Gastro-oesophageal reflux in children.
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Effect of posture on gastro-oesophageal reflux in the newborn.
The effect of posture on gastro-oesophageal reflux was studied by giving 72 orogastric tube feeds to 18 low birthweight babies. Each infant was studied in each of 4 positions: prone, supine, right, and left lateral. Brilliant blue was added to feeds and reflux was determined by staining of a cotton thread opposite the holes in a feeding tube passing from the nose to the distal oesophagus. A comparison of the prone and supine positions showed that significantly less reflux occurred in the prone position.
Recurrent abdominal pain and lactose intolerance in childhood.
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Controlled trial of cromoglycate and slow-release aminophylline in childhood asthma.
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Nursing jaundiced babies on lambskin.
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Dosage guidelines for slow-release aminophylline in childhood asthma.
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Hypoproteinaemia, oedema, and anaemia: an unusual presentation of cystic fibrosis in dizygotic twins.
The rare combination of oedema, hypoproteinaemia, and anaemia as a presenting feature of cystic fibrosis in dizygotic twins of opposite sex is described. The features of this syndrome together with pathogenesis, treatment, and prognosis are discussed.
Gastric emptying of Caloreen meals in the newborn.
The gastric emptying of 10% solutions of glucose and of Caloreen, a glucose polymer, was compared in 16 newborn infants. Caloreen left the stomach more rapidly than glucose on all but one occasion. This has potential advantages to infant feeding.