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Biomedical subjects

I Bruderman

Publications and source records attributed to I Bruderman.

At least 73 records · Page 4Linked to original sources
PubMed1976

Primary diffuse pulmonary amyloidosis with monoclonal gammopathy.

A rare case of primary diffuse amyloidosis of the lung with an abnormal monoclonal protein is described. The diagnosis was confirmed by an open-lung biopsy. The different classifications of amyloidosis as well as the relationship between the immunoglobulins and the pathogenesis of amyloid disease is discussed.

Aged↗
PubMed1975

Functional characteristics of the lung in chronic uremia treated by renal dialysis therapy.

Ventilatory studies and arterial blood gas analyses were performed in 29 patients with chronic renal failure undergoing renal dialysis therapy (RDT). Twenty-three of the 29 had nearly normal pulmonary function, and the accumulation of body water between dialyses did not influence pulmonary function significantly. A trend was observed towards overinflation and air trapping in the presence of normal airway resistance, indicating narrowing of the small airways. Repeated studies over a 16-month period suggest that these patients develop neither chronic obstructive airway disease nor restrictive ventilatory impairment. Six patients had a restrictive ventilatory impairment with a trend to overdistension and air trapping as in the "normal" patients. This was observed both early and late in the course of RDT and appeared to be irreversible but not progressive. These patients had suffered from uremic pleuropericarditis and either had serous effusions or residual adhesions.

Adult↗
PubMed1975

Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis.

Diagnostic and therapeutic problems in a patient with ectopic ACTH syndrome caused by a malignant bronchial adenoma are discussed. Persistent Cushing's syndrome was present following apparent total adrenalectomy, but radioactive scanning with 131I-19-iodocholesterol showed the presence of residual adrenal tissue in the right suprarenal bed. Amelioration of the hypercortisolism occurred after removal of the bronchial adenoma. A paradoxical elevation of adrenocortical activity followed administration of dexamethasone and data are presented which suggest that periodic secretion of ACTH accounted for this phenomenon.

Adenoma↗