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Biomedical subjects

I Helin

Publications and source records attributed to I Helin.

64 records · Page 4Linked to original sources
PubMed1977

Microanatomy of the intravesical ureter in children with and without reflux.

The microscopical appearance of 37 distal ureteral resection specimens from 27 children with recurrent urinary tract infections and vesicoureteral reflux are compared to postmortem specimens of 51 distal ureters from 28 children with no history or urinary tract disease. The degree of fibrosis and inflammatory change varied a great deal in both groups and it was not possible to find any differences between them.

Child↗
PubMed1975

Renal blood flow and function during neuroleptanaesthesia and at elevated intravesical pressure. An experimental study in the pig.

During two hours of neuroleptanaesthesia in five pigs, renal blood flow was unchanged, whereas renal vascular resistance and the mean arterial blood pressure increased. The glomerular function was not significantly altered. The tubular function was moderately impaired. The intravesical pressure was successively elevated in seven pigs. This caused no changes in renal blood flow. The renal vascular resistance increased parallelled by a slight increase of the mean arterial blood pressure. Both glomerular and tubular function decreased when the intravesical pressure was elevated to 50 mm Hg or above.

Animals↗
PubMed1975

Renal blood flow and function at elevated ureteric pressure. An experimental study in the pig.

The unilateral ureteric pressure was successively elevated in five piglets. Bilateral studies of renal blood flow and related parameters (cardiac output, renal vascular resistance, mean arterial and mean venous blood pressures) revealed no significant changes. At a unilateral ureteric pressure of 10 mm Hg, there was a temporary decrease in the renal vascular resistance in both kidneys concomitatnt with an increase in renal blood flow. Glomerular and tubular function decreased successively as the unilateral ureteric pressure was increased. At a retrograde pressure of 75 mm Hg, some renal function was still preserved, probably due to pyelolymphatic backflow.

Animals↗
PubMedDate not supplied

Brucella arthritis in children.

A study in 50 children suffering from acute brucellosis demonstrated that acute arthritis is a common and often predominant manifestation of the disease. The patients lived in an area where brucellosis is endemic: their ages ranged from six months to 12 years. All patients had a brucella agglutination titer of greater than or equal to 1:320 on admission. The knee and hip joints were most commonly affected with symptoms and findings from only one joint predominating. Associated findings of only moderately elevated ESR and normal leucocyte counts with relative lymphocytosis in the vast majority of the cases made it fairly easy to distinguish acute brucella arthritis from septic arthritis of other origin. A positive blood culture for Brucella melitensis was obtained in 35 of the patients. Treatment with tetracyclines, trimethoprim-sulphamethoxazole, with or without combination with streptomycin, resulted in a prompt recovery in all patients. No mortality was seen. Seven patients were readmitted with reinfections during a mean follow-up period of 13 months. Two patients with a history of prolonged fever, malaise and arthralgia were found to have osteomyelitis of the adjacent bone tissue. They also recovered without sequelae.

Acute Disease↗
PubMedDate not supplied

Occurrence of P-fimbriated Escherichia coli in urinary tract infections.

The occurrence of Escherichia coli possessing P blood-group-specific adhesins (P-fimbriae) was examined in 97 children with urinary tract infections and 82 healthy controls. P-fimbriae were present in 91% (33/35) of the urinary strains causing acute pyelonephritis. Among strains causing cystitis and asymptomatic bacteriuria P-fimbriae were found in 19% and 14% of cases, respectively. Only 7% of faecal isolates from healthy controls carried P-fimbriae. The results were similar in three different studies. In most of the children with acute pyelonephritis the urinary pathogen was the predominant E. coli strain of the periurethral and faecal flora.

Blood Group Antigens↗