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Biomedical subjects

I Jakobsson

Publications and source records attributed to I Jakobsson.

44 records · Page 3Linked to original sources
PubMed1979

A prospective study of cow's milk protein intolerance in Swedish infants.

1 079 of 1 548 newborn infants were followed during their first year. 328 were prospectively contacted once a month. 751 were followed up at child welfare clinics. Altogether 20 were diagnosed as being cow's milk protein intolerant (1.9%). Symptoms from the gastrointestinal tract and the skin predominated. Only 2 had respiratory symptoms. Ten had their symptoms within one week after the introduction of cow's milk, 3 of them at their first cow's milk-containing meal. A further 4 already had symptoms when fed only human milk. The others (6 infants) showed symptoms after more than one week on a cow's milk containing diet. Before 2 years of age, 13 had recovered. Twelve of the cow's milk protein intolerant infants also showed adverse reactions to other foods, soy-protein intolerance being the most common (7 infants). A family history of allergy was found in 35% (116) of the 328 infants and in 70% (14) of those with cow's milk protein intolerance.

Age Factors↗
PubMed1979

Do pre- and postchallenge small intestinal biopsies help to diagnose cow's milk protein intolerance?

Twelve infants suspected of cow's milk protein intolerance were challenged with cow's milk after at least one month of cow's milk-free diet. The challenge was clinically positive in seven. Small intestinal biopsies were taken with a multipurpose capsule both pre- and postchallenge (at 24 h) in eight, prechallenge in three, and postchallenge in one. Two or three biopsy specimens were taken at the same time in 15 of the 20 biopsy occasions. The morphology of the mucosa could vary from normal to slight damage at the same biopsy occasion. No difference was found in morphology judged by light microscopy between pre- and postchallenged biopsies. Light microscopy of small intestinal biopsies taken before and at 24 h after milk challenge seems of doubtful value as a routine diagnostic means in cow's milk protein intolerance.

Animals↗
PubMed1978

Cow's milk as a cause of infantile colic in breast-fed infants.

18 mothers of 19 breast-fed infants with infantile colic were put on a diet free of cow's-milk protein. The colic disappeared promptly from 13; in 12, it reappeared on at least two further indirect challenges (in the form of a diet containing cow's milk to the mother). Most infants became symptom-free at age 2 to 4 months; at 4 months, only 4 reacted with colic when the mother took cow's milk. 5 infants were directly challenged with cow's milk; 4 reacted promptly with colic. Other signs of intolerance to cow's-milk protein developed in 3 infants during weaning. The treatment of infantile colic in breast-fed infants by a diet free of cow's milk for the mother appears worthwhile.

Adult↗
PubMedDate not supplied

Unusual presentation of adverse reactions to cow's milk proteins.

Allergy to cow's milk most commonly give symptoms from the gastrointestinal tract, the skin or the respiratory tract. Here two patients are described, with symptoms not so common. One with cerebral symptoms and the other with enuresis. Infantile colic occurs more or less in about 20% of all infants. We have found that in about 1/3 of breastfed infants with infantile colic the symptoms disappeared when the mothers had a cow's milk free diet. We have also managed to analyse the content of the cow's milk protein beta-lactoglobulin in the human milk.

Animals↗