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Biomedical subjects

I M Ali

Publications and source records attributed to I M Ali.

25 records · Page 2Linked to original sources
PubMed1994

Carotid body tumor associated with hyperparathyroidism.

Hyperparathyroidism in association with carotid body tumor is a rare combination. A common embryologic cellular origin was postulated previously to explain this unusual occurrence. We report a case of left carotid body tumor and left inferior parathyroid adenoma. We believe this to be the sixth reported case in the literature with this combination.

Adenoma↗
PubMed1994

The safety of intermittent warm blood cardioplegia.

Continuous warm blood cardioplegia is considered to be an effective method for myocardial protection. However, frequently the flow of the cardioplegia needs to be interrupted for better visualization. Intermittent warm blood cardioplegia was reported to be safe by some investigators. To assess the degree of this safety, 76 patients who underwent operations for coronary or valvular disease, or both, were divided into two groups of 38 patients each. The two groups were well matched for age, ejection fraction, number of coronary bypasses and type of valvular procedures. Cold blood cardioplegia (CBC) was used intermittently every 15 min in the first group while the second group received warm blood cardioplegia (WBC) intermittently every 15 min. The clamp time range was 50-140 min. There were no deaths in either group, four myocardial infarctions occurred, two in each group. Low cardiac output occurred in 13 patients of the WBC group and in 7 patients of the CBC group, electrocardiogram (ECG) global ischemic changes were recorded in 14 patients of the WBC group compared to 6 patients of the CBC group. Statistically the results indicate that the techniques are comparable if the clamp time is less than 90 min. However, after 90 min the development of ECG changes and low cardiac output are significantly higher when WBC is used P < 0.001. Therefore, it is concluded that using the WBC intermittently is as safe as CBC when the clamp time is less than 90 min, however extra precautions are needed with longer clamp times.

Aged↗
PubMed1990

Modification of supraventricular tachyarrhythmias by stimulating atrial neurons.

The effects of stimulating the right atrial ventral ganglionated plexus on ventricular performance during atrial tachycardia was studied in 8 lightly sedated (pentobarbital, 2.5 mg/kg intravenously) dogs with sterile pericarditis. Atrial arrhythmias were induced by electrical stimulation (10 V, 4 ms, 100 Hz) of the right atrium through previously inserted temporary bipolar pacemaker wires. Various types of supraventricular tachycardias were produced. Atrial fibrillation was produced in 3 dogs, atrial tachycardia in all 8 dogs, different atrioventricular nodal ectopic rhythms in 6 dogs, and atrial flutter in 1 dog. These arrhythmias were associated with irregular ventricular contractions that resulted in low ventricular pressures during many cardiac cycles such that low or no aortic pressure was generated. Right atrial ventral ganglionated plexus stimulation induced slowing of ventricular rate so that every ventricular contraction resulted in aortic pressure generation, thus increasing mean aortic pressure. Responses elicited by atrial ganglionated plexus stimulation were eliminated after atropine administration. We conclude that electrical stimulation of the right atrial ventral ganglionated plexus results in slowing of ventricular contractile rate during supraventricular tachycardia, presumably by activating efferent vagal neuronal elements, thereby improving ventricular performance. If applicable in humans, this technique may be of use in management of postoperative atrial arrhythmias after cardiac operations.

Animals↗