[Significance of hypothermia in renal surgery].
Explore the source record for details and available documents.
Humans↗
Biomedical subjects
I Mikó
Publications and source records attributed to I Mikó.
Auto-alloplastics closure of cervical esophageal fistulae.
The authors performed auto-alloplastic replacement with flap through a round incision, 20 to 22 in mm diameter, to elaborate a suitable method for closing the fistulae which may from during cervical esophageal operations. Of the animals three died due to other causes, the others could be evaluated, and, although the operated esophagus had not been relieved from inner pressure, after 24 hours the animals were capable of drinking, later eating. The auto-alloplastic flap was followed up by histological examination for six months.
Animals↗
Experimental in situ renal hypothermia through the renal vein.
The authors worked out the technique of in situ renal hypothermia in dogs by direct cannulation of the renal vein or through the internal spermatic vein (ovarian vein). The technique is suggested for preventing the ischaemic impairment of the renal parenchyma in operations requiring compression of the renal artery for more than 20 minutes.
Animals↗
Experimental study of suture materials placed in the renal parenchyma.
Absorbable and non-absorbable suture materials in the renal parenchyma were examined in comparative studies performed on 12 mongrel dogs. Quantitative and qualitative histological studies showed that Dexon was preferable to other absorbable suture materials as opposed to traditional catgut, while Supramide and Polyester had certain advantages over other non-absorbable materials.
Absorption↗
The role of ischaemia in the formation of postoperative intra-abdominal adhesions.
The formation of intra-abdominal adhesions was studied in animal experiments. In dogs, the peritoneal lining was eliminated on the left side of the abdominal wall, while ischaemia was elicited contralaterally by suturing the main vessels. Two to seven weeks later no omental adhesion could be found on the abdominal wall deprived of peritoneum, while it developed in 11 of the 13 operated animals in the ischaemic area.
Abdominal Muscles↗
Comparative studies on bioplasts used for the closure of wound surfaces of the pancreas.
The solubility of four types of bioplasts was studied in vitro in homogenized pancreas tissue. In parallel experiments the resection surface of pancreas in dogs was covered with the same materials. "Collagen" and "Surgicel" proved to be more resistant to pancreatic juice than other bioplasts and in vivo results were also better in these cases.
Animals↗
Sutures inserted into the gastric wall an experimental study.
Thirty gastrotomies were performed in 15 dogs using 2/0 atraumatic needles. Various kinds of threads were used: Dexon as an absorbable suture, Black Perlon and Black Braided Silk as nonabsorbable sutures. Ten suture rows were made with each material. Single-row interrupted sutures were made with no suture in the mucosa. No suture insufficiency occurred. Dexon proved to be the most suitable material, although the nonabsorbable sutures did not cause complications, either.
Animals↗
Comparative studies with extracorporeal hypothermal kidney perfusion.
Various solutions of extra- and intracellular, or non-electrolyte type supplemented with papaverine or lidocaine were administered by gravity perfusion to 60 dog kidneys. Cooling in the kidneys perfused with the solutions containing papaverine lowered the temperature of kidneys in significantly shorter time than in those containing lidocaine. The histological examinations revealed good perfusion with solutions containing papaverine; even the rim of the cortical substance has been freed of blood. Identical results could not be achieved with lidocaine. These results are to be considered in the clinical work.
Animals↗
Intraductal pressure in experimental chronic pancreatitis and the magnitude of decompression after different types of operation.
The intraductal pressure parameters were studied in dogs with chronic pancreatitis. A ductal hypertension, similar to that in human chronic pancreatitis was demonstrated. Pressure fell after all different decompression procedures applied but it was most significant after longitudinal pancreatojejunostomy.
Animals↗
[Securing anastomosis of the large intestine with glued autologous tissue].
The colon was cut through across in 32 dogs without essential preparation. The recombination of the ends was carried out by a single-row stitched suture. This one was covered with an autologous strip of parietal peritoneum and fascia which was stuck by histoacryl-N-blue. The results were good after practising this technique.
Animals↗
Experimental partial splenectomy.
Partial splenectomy was performed on 25 dogs, removing the lower third of the spleen by a transverse incision. Stronger bleeding was ligated while parenchymatous haemorrhage was covered with Gelaspon plus Topostasin or Surgicel. The substances were sutured to the spleen with Dexon suture. Both substances proved advantageous, but the application of Gelaspon induces less tissue reaction and results in thinner neocapsule.
Animals↗
[Experimental surgery of the choledochus].
The authors carried out choledochal grafts in dogs with autologous parietal peritoneum and adjoining fascia of the musculus rectus abdominis. The patch was fixed with the tissue adhesive hystoacryl without suture. Additionally there was used an interior splinting with a polyethylene tube coated with paraffin. The inserted tube rubed off itself in case of a proper size. Adhesive must not get into the choledochus. 15 of the 20 experiments in dogs were successful.
Animals↗
Comparison of suture materials in the pancreas.
Comparative tests were performed in animal experiments with traditional and new suture materials placed into the pancreas. Dexon and polyester caused the least tissue reaction and their reaction indices were the most favourable. These threads therefore appear the most suitable for making sutures in the pancreas.
Animals↗
[Experimental studies of circulation following a plication operation].
Three types of plications were performed on dogs: 1. modified mesenterial plication; 2. transjejunal internal splinting; 3. intestine duplication according to Noble. No passage disorder or abnormal circulation were observed; compared with the values of the control dogs isotope activity was the same after plication. Thus, there is no danger of impaired circulation after this type of operation.
Animals↗
[Pressure conditions in the pancreatic duct in acute experimental pancreatitis].
The pressure conditions in the pancreatic duct of healthy dogs and of animals with experimentally induced acute serous or necrotic pancreatitis were studied with the Hess-type manometer successfully applied in biliary surgery. In acute pancreatitis hypertension was observed which was more marked in the group with necrotic pancreatitis.
Acute Disease↗
Comparison of suture materials for intestinal anastomosis.
Ninety end-to-end entero-anastomoses were prepared in 45 dogs by inverted single row knotted sutures. Half of the anastomoses were carried out on the small intestine, the other half on the colon. Of the two non-absorbable materials that of the polyester type proved to be the best. Of the absorbable materials Dexon can be recommended for intestinal anastomoses, but on the colon Dexon is not reliable. Plain catgut is not recommended for this kind of anastomoses.
Animals↗
Histologic demonstrability of surgical adhesive.
Explore the source record for details and available documents.
Histological Techniques↗
Experimental dermatoplasty of skin defects with an absorbable bioplastic preparation.
Experimental dermatoplasty was performed with fibrin sponge preparation in the rabbit, during the course of which the whole skin thickness was substituted. The fibrin sponge was fixed to the skin-edges with surgical adhesive. The gradually absorbed fibrin was replaced by the migrating epithelium such that epithelization developed gradually. In special cases this method can be recommended for clinical purposes.
Animals↗