Biomedical subjects

I Moroz

Publications and source records attributed to I Moroz.

3 recordsLinked to original sources

PubMed1998

Bilateral Kimura's disease with devastating visual outcome.

Kimura's disease is a chronic inflammatory disease involving connective tissues. We treated a patient with bilateral periocular Kimura's disease causing eyelid deformity and exophthalmos for over 20 years. She has been operated on 23 times and biopsies were taken and studied histologically. The disease continued despite the multiple surgical excisions. The consequent exophthalmos and lid changes caused lagophthalmos that resulted in severe visual impairment due to chronic bilateral corneal exposure. Kimura's disease may have a devastating effect on visual function.

Angiolymphoid Hyperplasia with Eosinophilia↗

PubMed1997

Ibogaine interferes with the establishment of amphetamine place preference learning.

The ability of ibogaine, injected 24 hr before amphetamine, to modify the establishment of amphetamine-induced place preference learning was assessed. A single injection of ibogaine blocked the establishment of amphetamine place preference after 1 or 2 conditioning trials, but it was less effective after 4 trials. The reduced effectiveness of ibogaine across multiple conditioning trials appears to be the result of the development of tolerance to ibogaine.

Amphetamine↗

PubMed1995

Morphine-induced taste avoidance is attenuated with multiple conditioning trials.

Morphine has paradoxical effects in learning experiments. The drug can serve as a reinforcer in several situations; yet rats avoid tastes paired with morphine, much as they avoid tastes paired with an emetic drug such as lithium chloride (LiCl). The results of the present experiment indicate that, in contrast with LiCl-induced taste avoidance, the strength of morphine-induced avoidance is nonmonotonically related to the duration of training. Although taste avoidances produced by both drugs are readily established, the morphine-induced avoidance (unlike the LiCl-induced avoidance) weakens with continued flavor-drug pairings. These results, together with prior findings, suggest that there are distinctive features of morphine-induced taste avoidance.

Animals↗