A total of 250 patients with diagnosed bronchial asthma (BA) were examined by microbiological methods. Among them--188 children and 62 adults. In 87 patients the microflora of nasal mucosa was studied, in 40--of pharynx only and in 123 patients--both the nasal and the pharynx. For comparative analysis earlier data obtained in 69 patients with persistent allergic rhinitis (PAR) were used. The cultures isolated from the nasal mucosa of BA patients were shown to number 18 genera and 42 species, while among those isolated from pharynx mucosa 20 genera and 40 species. Monocultures were isolated from the nasal mucosa only in 23% of the examined patients and from the pharynx mucosa--only in 1.42%. Associations with different numbers of components were isolated from nasal and pharynx mucosa (2 to 6, 2 to 8 respectively). Staphylococcus aureus was regarded as the main species of nasal biocenosis in BA and PAR, as well as pharynx biocenosis in BA. Besides, in BA other Staphylococcus species (schleiferi, caprae, capitis, hominis, etc.), reversely related to the main species, could be isolated from both mucous membranes. Similarities and differences in microflora of biocenoses in both nosological forms, confirming links between PAR and BA, are considered.

Adult↗

PubMedDate not supplied

[The characteristics of the intestinal Escherichia microflora in patients with acute intestinal infections].

The content of enterobacteria in fecal samples obtained from 1,146 patients with acute enteric infections was studied. In the first days of the disease about 70% of the patients were found to have abundant and highly diversified intestinal microflora with Escherichia contamination of feces constituting 10(6)-10(7) microbial cells/g in children and 10(7)-10(8) microbial cells/g in adults. The number of patients excreting Escherichia and pathogenic enterobacteria increased from 8.8% (children under 6 months) to 28.6% (adults), the number of patients excreting Escherichia and opportunistic enterobacteria decreased from 69.1% (children under 6 months) to 36.8%. In 75% of cases the reverse relationship between the number of Escherichia and opportunistic enterobacteria was registered, the latter numbering two and more genera in 50% of cases. The serological picture of Escherichia was poorer when they were isolated simultaneously with shigellae (83 O-groups) than in those cases when Escherichia alone were isolated (108 O-groups), or when Escherichia were isolated simultaneously with opportunistic enterobacteria (119 O-groups).

Acute Disease↗

PubMedDate not supplied

[The hemagglutinating and fermentative properties of different O-serogroups of Escherichia isolated from healthy children and urology patients].

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Bacteriuria↗

PubMedDate not supplied

[The need for revision of the bacteriological criteria of the etiological significance of diarrheogenic Escherichia strains in the diagnosis of acute intestinal infections].

Different E. coli of 0-groups, enteropathogenic (EPEC), enteroinvasive, enterotoxigenic (ETEC) and diarrheogenic in sporadic child diarrhea (DESCD), regarded as the causative agents of enteric infections, were detected in 70-80% of cases (1,146 E.coli carriers) in the feces of child and adult patients with acute enteric infections (AEI) irrespective of their age; in 35% of cases the same patient had a combination of two or more varieties of EPEC, ETEC or DESCD. Only EPE were excreted by 3.5-11.3% of patients, depending on their age; only ETEC were excreted by 1.7-3.4% of patients and only DESCD, by 23.1-32.8%. In 30-40% of cases diarrheogenic E.coli of the corresponding 0-groups were isolated as monocultures. The complex of bacteriological criteria, serving as the basis for the diagnostics of AEI (the necessity of the quantitative and qualitative characterization of the contamination of the seed material, E.coli serological labeling, the determination of E.coli pathogenicity factors) is discussed.

Acute Disease↗