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Biomedical subjects

I Popiliev

Publications and source records attributed to I Popiliev.

At least 19 recordsLinked to original sources

[The characteristics of repeated myocardial infarcts in men and women].

117 patients, 89 men and 28 women, with repeated myocardial infarction were followed up for a two year period. The following were taken into consideration: risk factors, number and localization of previous infarctions, interinfarction period, clinical onset of the new infarction, complications, electrocardiographic changes, time of death, causes of death, pathologicoanatomical localization of the new and old infarctions in comparison with the electrocardiographic localization. Statistically significant differences between the two sexes were found for the death of cardiogenic shock--48.9% for men and 13.3 for women (p less than 0.01) and for chronic cardiac failure as a complication of the second myocardial infarction--50.0% for women and 16.1% for men (p less than 0.001). For all other indices the differences were not statistically significant.

Aged↗

[The characteristics of those who have died with primary or recurrent myocardial infarct].

In 93 decreased patients, 31 with first myocardial infarction and 62 with repeated myocardial infarction, the following indices were studied: risk factors, previous history, clinical onset, complications, ECG localization, time and cause of death, pathologicoanatomical changes. There was a tendency toward a greater frequency of cardiogenic shock in the patients who died during their first infarction. In the patients who died during a repeated infarction the following events were significantly more frequent: pulmonary thromboembolism (9.6%), dilatation (8.1%), recurrence (8.1%) (p less than 0.01); chronic cardiac failure (25.8%), episodes of clinical death (25.8%) (p less than 0.001); conduction-rhythm disturbances (75.8%) (p less than 0.05). Transmural infarction was found in 96.7% of the patients of the first infarction group vs 82.2% of the patients of the repeated infarction group (p less than 0.05). A statistically significant difference for the time of death was found only for the group patients who died after the 7th day of the infarction--0% for the first infarction group and 25.8% for the repeated infarction group (p less than 0.001). Cardiogenic shock was a significantly more frequent cause of death for the patients of the first infarction group (87.1%) than for the patients of the repeated infarction group.

Age Factors↗

[Hypokalemia caused by nifedipine].

A case of 72 year old woman with arterial hypertension is presented. The woman was treated with clonidine and nifedipine. Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents. It is assumed that the hypokalemia was due to the nifedipine treatment.

Aged↗

[Clinico-pharmacologic study on the liquid form of nifedipine in treating hypertensive crisis].

33 patients with hypertensive crisis were treated with a 2% Nifedipine solution for oral use. 5 patients had taken 5 mg, 16 patients--10 mg and 12 patients--20 mg of the drug. The antihypertensive action was followed up to the 6-th hour. The results show that the antihypertensive action of Nifedipine in doses of 5, 10 and 20 mg begins on the 5-th minute. The maximum antihypertensive action of these three doses is manifested between the 15 and 30 min. The duration of Nifedipine action in a dose of 5 mg is up to the 2-d hour and that of 10 and 20 mg doses is up to the 6-th hour. Only the 20 mg dose leads to a transitory statistically significant increase of the pulse rate with 10-12(-1) (p less than 0.05) between the 15 and 30 min. The side effects of the three doses are insignificant.

Administration, Oral↗

[Critical assessment of the criteria proposed for the ECG diagnosis of atrial loading].

Some criteria, proposed for the diagnosis of auricle loading have been evaluated during the study of 210 healthy subjects--87 patients with left auricle loading (LAL) and 71 patients with right auricle loading (RAL). The total duration of P wave differentiates a smaller LAL than the duration of PII. The ratio of P duration to PP segment in V1 has a poor specificity. The phenomena interatrial conduction disorder with left auricular retrograde activation has a low sensitivity on EGC for LAL, and with the orthogonal EGC--low sensitivity and specificity. The ratio of duration to amplitude of PII has a restricted value. LAL and RAL differ significantly but they are very bad results in the stages of left auricular dilation. The various ways of evaluation of the electric axis (digital or in degrees) have their place in the multidirectional pathological deviations--LAL and RAL.

Adult↗

[Analysis of the indices of patients who died from single and recurrent myocardial infarcts].

The author analyzes the percentage of deceased, age distribution, participation of risk factors, mean number of days at the hospital of the deceased, some clinical symptoms of the disease, complications, anatomic localization of the disease, ECG changes, anatomically established aneurysms and rupture, as well as the non-coincidence of clinical and anatomical diagnosis in both forms of the disease. The most important discrepancies in the indices discussed are underlined.

Adult↗

[Effect of nonpathological factors on the atrial segment of an orthogonal ECG in healthy persons].

The effect of deep breathing and shifting of the electrodes along the horizontal line was followed up in four orthogonal ECG systems. The duration of P wave did not change during deep breathing. The amplitude of P wave increased in the traditional ECG, simulating right atrial loading in the traditional ECG. The amplitude of Px decreased in OECG but it cannot lead to diagnostic difficulties. With the shifting of the electrodes (within the involuntary errors) OECG systems of McFee--Parungao and SVEK III are not liable to shifting of the electrodes and that of Frank shows an increase of the amplitude of the negative part of P z as in right-atrial loading.

Adult↗

[Clinico-anatomical characteristics of recurrent infarction pulmonary thromboembolism].

The results are reported from a retrospective study on the case histories of 41 deceased with recurrent infarction form of pulmonary thrombembolism. That form of the disease for a period of 5 years (1980-1984) was established to be found in 19.1% of all cases with pulmonary thrombembolism. The males were more often affected, with the predomination of the patients over 60 years of age; the patients with internal diseases were more than the surgical patients, with a probable origin of emboli from the femoral and pelvic veins in 58.5%. The most frequent clinical symptoms are dyspnea, tumid cervical veins and moist rales in the lungs. More than half of the patients manifest "masks" of the disease, broncho-pulmonary being the most-often established one.

Adult↗

[Clinico-morphological characteristics of pulmonary thromboembolism in decompensated heart patients].

The results from the studies on the case histories of 115 deceased decompensated cardiac patients with pulmonary thromboembolism are reported in the paper. It was established that those were mainly elderly people, both sexes almost equally engaged. The probable origin of embolism is analyzed in details as well as the concomitant diseases, anamnestic and clinical symptoms, some paraclinical deviations and the course of the disease. The involvement of the trunk or main branch and of the middle and small branches of pulmonary artery were separately discussed. Some differences are emphasized with the two localization of pulmonary thromboembolism. Finally, the various forms of the disease (cerebral, pulmonary, cardiac and abdominal) are discussed in details, with attention paid to the possible errors with them.

Adult↗

[Comparative studies with 4 orthogonal electrocardiographic systems of patients with right-ventricular hypertrophy].

One hundred and four patients with established mainly clinical right ventricular hypertrophy were studied (in three age subgroups, separately males and females). The predominating diseases were decompensated pulmonary heart (54 patients), mitral stenosis (45 patients). The orthogonal ECG systems of Frank, McFee , SVEC III and Akulini cev were used. The results from 40 patients were also discussed that were also with right ventricular hypertrophy but established by some other methods. The examinations of 103 healthy subjects served for comparison. The younger (mainly patients with mitral stenosis) were established to have changes in SY whereas the changes in the older were mainly in SX and QZ RZ. Consideration given to the indices--duration of SX over the norm and RX/SZ less than 1 with Akulini cev method and the duration of SY over the norm and RY/SZ less than 1, the systems of McFee and SVEC III proved to be with best diagnostic accuracy in right ventricular hypertrophy.

Cardiomegaly↗

[Comparative studies with 4 orthogonal electrocardiographic systems of patients with bilateral ventricular hypertrophy].

One hundred forty five patients were examined, with established mainly clinically, bi-ventricular hypertrophy of three age subgroups, males and females separately and with the diagnosis, mitral-aortic heart defect, congestive cardiomyopathy, pulmonary heart with arterial hypertension and congenital heart defect with left-to-right shunt. The orthogonal electrocardiographic systems of Frank, McFee , SVEC III and Akulini cev were used. Additionally, the results from 54 patients were discussed that had bi-ventricular hypertrophy definitely established by some other methods. The examinations of 103 healthy subjects served for comparison. The signs of left ventricular hypertrophy (RX RZ over the norm) were established to be well manifested by all systems used and at all ages, whereas the right ventricular--with increased SY in the younger patients and SX--in the older ones. Consideration given to the sum of the electrocardiographic indices of left- and right-ventricular hypertrophy, it could be said, that the systems of McFee and SVEC III, from all the orthogonal ECG systems used, are with the highest diagnostic accuracy in bi-ventricular heart hypertrophy.

Adult↗

[Electrical position of the heart and its variants in a new electrocardiographic system with 9 bipolar leads].

Consideration given to the position type of the traditional ECG, the changes in the amplitudes of R, S and T were discussed in the system with 9 bipolar leads (A-I), grouped according to age and sex in 151 healthy subjects with the leads on the back (H and I) the alteration and Q deflection were assessed. The results in each position type are compared with those of the whole group with the respective age and sex. In the first age group (20-29) the vertical position showed alteration only among the females (increase of SA and reduction of RHI), whereas the indifferent position--only among the males (increase of RF and reduction of SHI). In the second age group (30-44) the vertical position showed an increase of the amplitude of SCE among the males, whereas among the females--RH and QHI were reduced, but SHI increased; the indifferent position showed changes only among the females (increased RD) whereas the horizontal (only females) showed a reduction of SABCHI. In the third age group (45-60) the indifferent position showed changes only among the females (increased amplitudes of SA and QHI); the horizontal position among the males showed an increase of RB, and among the females--increased of QH and reduction of SBHI. The negative T-deflections are mainly found among the younger subjects, in the first leads in front (A-C), and more often--among the females. The possibilities for differentiation of the altered Q deflection in the leads H and I are discussed, with a view to acute or healed inferior-diaphragmatic myocardial infarction.

Adult↗

[Electrical positions of the heart and its variants in orthogonal electrocardiographic systems].

In a total of 151 healthy subjects the changes in the orthogonal electrocardiographic systems of Frank, McFee, SVEC III and Akulinicev were followed up, in the groups with vertical indifferent and horizontal positions, grouped into three age subgroups and according to age. They were compared with the general groups of the corresponding age and sex. It was established that at the age from 20 to 29, the changes with the systems of Frank, McFee and SVEC III were in RY, in both sexes that index, at vertical position, was increased versus the general group; at indifferent position the same index showed a reduction in males. Akulinicev system revealed changes of SX (increase) and SY (decrease) only at vertical position and only in females. At the age from 30 to 44 the vertical position in both sexes revealed changes only in RY (increase) with Frank, McFee and SVEC III, whereas the horizontal position revealed a decrease of the same index. At the age from 45 to 60 years, changes in some of the systems were established only at the horizontal position--increase of RX mainly in males and with some systems in females--reduction of RY. The statistically significant changes in the individual indices at the various positions subgroups are discussed as well as the possibilities of their differentiation from pathological states (left- and right-ventricular hypertrophy).

Adult↗