[EEG aspects of chronic alcoholism].
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Biomedical subjects
Publications and source records attributed to I Roman.
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Pre- and post-pubertal Wistar rats were injected i.m. with a single dose equivalent to 1 UI of Calcitonin (Calsyn-50 Rorer, Swiss). Its effects upon the thymus and adrenals were assessed after 1, 3 and respectively, 8 days since injection. The results pointed to differences of reaction of the thymus and adrenals dependent on rat ages and on the period of hormone persistence in the organism. The effects in mature rats are characterized by a stress state, reflected in adrenal reaction, but without impact upon the thymus in point of biochemical parameters. In rats of that age, modifications in both organs are much reduced after 8 days since calcitonin injection. In pubertal rats, adrenal activity is temperate, and thymus registers modification of DNA, of oxygen consumption and of nitrogen aminic after 3 days since injection. This modification is maintained for 8 days.
Administration of L-thyroxin in a dose of 30 micrograms/chicken, i.m. and 2-thiouracyl in a dose of 0.3 mg/chicken, i.m. for an interval of 3 days, determined, at the thymus level, increases of total protein content in the Tu group, in parallel with decreases of the nitrogen of free amino acids level in the Tx group, increases of DNA content in the Tx group and an increase of the thymus weight in both groups. Modifications are due to the action of thyroxin, on the one hand, and on the other to the doses of antithyroid drug which determines a raise of T4 content in the plasma and the manifestation of activities specific to this hormone.
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Cornish-Rock chickens were given 0.3 ml anti-bursal serum in the pectoral muscle on the first day of life. Three days after serum administration, the modifications were evident both in the bursa of Fabricius and thymus (ponderal involution and decrease of RNA and glycogen contents). Pronounced thymo-bursal differences appeared at 13 days: in the bursa the values were normalized; in the thymus inverse modifications appeared as compared to the 3 days values. The modifications in the adrenals are in agreement with those in the lymph organs.
Administration of a unique dose of thiourea (7 mg per kg b.w.) in the 7th day of life to broiler chickens affects in different manners the jejunal absorption of glucose and that of leucine. Methionine supplementation of the fodder (1.5 g per kg) during 40 days affects--in an age-dependent manner--the glucose absorption, but not that of leucine.
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