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Biomedical subjects

I Szigetvári

Publications and source records attributed to I Szigetvári.

23 records · Page 2Linked to original sources
PubMed1976

The effect of allyloestrenol on human chorionic somatomammotropin synthesis of the placenta during normal pregnancy.

The effect of allyloestrenol on human chorionic somatomammotropin (HCS) level in healthy pregnant women in the fifth to eighth months of gestation has been studied by radioimmune techniques. The HCS level showed a significant increase within 10 to 12 days. According to the results, allyloestrenol exerts a stimulating effect on the placental steroids as well as on HCS production.

Allylestrenol↗
PubMedDate not supplied

Direct chromosomal preparation for studying hydatidiform moles.

This report describes a simple direct method to obtain chromosomes from hydatidiform moles. Of 24 moles, 20 have been successfully karyotyped by this method. Of the 20 cases, 14 were complete and six were partial. The karyotype of complete moles was invariably diploid. Three of the partial moles were triploid (69,XXX), but three showed diploid/tetraploid mosaicism.

Adolescent↗
PubMedDate not supplied

Effect of choriocarcinoma supernatant on natural killer and lymphokine-activated killer cell activity.

The effect of JEG-3 choriocarcinoma supernatant on human natural killer cell and lymphokine-activated killer cell activity was investigated. Choriocarcinoma supernatants from JEG-3 cell lines were obtained at the time of their optimal growth. K562 erythroblastoid cells were used as target cells for natural killer and lymphokine-activated killer cell mediated lysis in a 51Cr release assay. The choriocarcinoma supernatants had a significant dose-dependent suppressive effect on natural killer and lymphokine-activated killer cell activity. This suppression was more expressed at high effector: target cell ratios. Therefore, choriocarcinoma supernatants appear to have potent inhibitory effects on many aspects of cellular immunity, although, additional studies should be performed to further characterize and identify immunoregulatory molecule(s) in choriocarcinoma supernatants.

Choriocarcinoma↗