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Biomedical subjects

I Xess

Publications and source records attributed to I Xess.

7 recordsLinked to original sources

Invasive dermatophytosis with lymph node involvement in an immunocompetent patient.

A 23-year-old man presented with annular and arcuate, hyperpigmented, itchy, scaly plaques over the trunk and lower extremities for 5 years progressing to verrucous papules and nodules for the last 1.5 years. He also had nontender, inguinal and axillary lymphadenopathy. Skin and lymph node biopsies showed granulomatous inflammation and special stains demonstrated long septate hyphae. Tissue cultures grew Trichophyton verrucosum. The patient was treated with itraconazole 100 mg twice daily for 8 months, resulting in complete clearance of the lesions.

Adult↗

Bone marrow examination for identifying malaria in fever of unknown origin.

To determine the utility of bone marrow examination for the diagnosis of malaria in patients with persistent fever for prolonged duration, we prospectively studied individuals undergoing diagnostic bone marrow examinations between January 1992 to December 1996. All marrow examinations of patients were examined microbiologically and resulted in diagnosis of malaria in 6.6% of the total patients studied. No case of bacterial, mycobacterial or fungal infection was diagnosed. The diagnostic efficacy of bone marrow for evidence of malaria was very useful in febrile individuals for whom the diagnosis was otherwise unknown.

Adolescent↗

Is zero dose oral polio vaccine effective in preterm babies?

A randomized controlled trial was done to compare seroconversion following a single dose of trivalent oral polio vaccine (TOPV) in preterm babies, vaccinated at two different post-conception ages, with that of term newborns. Sixty-two consecutive preterm babies < or = 35 weeks were randomly allocated to two groups. Group A was vaccinated 'early' at 34-35 weeks and group B 'late' at 38-40 weeks post conception. The two groups were comparable in birthweight [mean (SD) 1594 g (118) and 1599 g (126), respectively] and gestational age [mean (SD) 33.2 (1.2) and 33 (1.3) weeks, respectively]. A control group of 36 term babies (group C) were vaccinated in the 1st week of life. Polio virus antibodies were measured immediately before and 6-8 weeks after vaccination. Group A had seroconversion rates of 54.2, 12.5 and 12.5% against polio virus types 1, 2 and 3, respectively, group B had rates of 60.0, 8.0 and 16.0%, and group C rates of 53.6, 10.7 and 14.3%. Differences in the seroconversion rates in the three groups were not statistically significant. The conversion rates against types 2 and 3 are much lower than in previous studies. We conclude that preterm babies vaccinated at 34-35 weeks post conception show seroconversion rates similar to those in term newborns.

Humans↗

Evaluation of a safe sputum processing method for detecting tuberculosis.

AIMS: To evaluate a safe sputum processing method for detection of tuberculosis in developing countries. METHODS: A sample processing method was developed in which acid fast bacilli were killed with 1% sodium hypochlorite and concentrated by flotation on a layer of xylene before staining by the Ziehl Neelsen or auramine O methods. RESULTS: Best results were obtained by auramine O staining after flotation. Staining by the Ziehl Neelsen method after flotation gave better results than direct Ziehl Neelsen staining without flotation. CONCLUSIONS: The flotation method with Ziehl Neelsen staining offers advantages for smear preparation in the tuberculosis control programmes of developing countries.

Bacteriological Techniques↗

Acute hemorrhagic conjunctivitis due to enterovirus 70 in India.

An outbreak of acute hemorrhagic conjunctivitis occurred in Delhi, India, during August and September 1996. The etiologic agent was confirmed as enterovirus type 70 by a modified centrifugation-enhanced culture method followed by immunofluorescence and neutralization tests. After nearly a decade, this virus is reemerging as a cause of acute hemorrhagic conjunctivitis in India.

Adolescent↗

The first major outbreak of dengue hemorrhagic fever in Delhi, India.

India An outbreak of dengue hemorrhagic fever/dengue shock syndrome (DHS/DSS) occurred in 1996 in India in and near Delhi. The cause was confirmed as dengue virus type 2, by virus cultivation and indirect immunofluorescence with type-specific monoclonal antibodies. This is the largest such outbreak reported from India, indicating a serious resurgence of dengue virus infection.

Adolescent↗