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Biomedical subjects

Iu L Shevchenko

Publications and source records attributed to Iu L Shevchenko.

At least 55 records · Page 3Linked to original sources

[Continuous inhalation administration of surfactant-BL for control of adult respiratory distress syndrome after reconstruction of the abdominal aorta].

A 62-year-old patient with Leriche's syndrome and critical ischemia of the low extremities has undergone the surgery of aortofemoral grafting. A patient has developed the severe ARDS on the second day of reperfusion (bilateral diffuse infiltrates, PO2/FiO2 < 100, lung injury score was 3). Different ways of administration of bovine surfactant (SURFACTANT BL, Russia) were used during the treatment. Total application time was 84 hours, total dose was 4000 mg (50 mg/kg). Considerable improvement of lung function occurred after start of the continuous inhalation of surfactant with a constant rate of 63 mg/h. Two hours after this step PO2/FiO2 reached 400 mm Hg and remained stable 12 hours more, up to the end of surfactant administration. The patient was soon successfully extubated and discharged on the 25th day after surgery. It is supposed that in spite of a small total dose of bovine surfactant the success was achieved due to an early start of the surfactant replacement, continuous inhalation and its definite rate.

Administration, Inhalation↗

[Erythropoietin in the prevention and treatment of anemia in heart surgery patients].

The authors present results of using recombinant human erythropoietin in patients operated on the heart under conditions of extracorporeal blood circulation. It was found that the intravenous infusions of erythropoietin at the postoperative period accelerated the restitution of circulating erythron indices. The volume of transfusion of the donor erythrocyte-containing media to the patient is given erythropoietin was reliably less than that in the control group. The results obtained allow using erythropoietin to be recommended as an effective method of prophylactics and treatment of anemia in cardiosurgical patients.

Adult↗

[The potentials of molecular genetic diagnosis in military medicine (a review of the literature)].

The practical importance of the main genetic infringements in diagnostics of a wide circle of illnesses, including cardiology, nephrology, and oncology. Methods used. The exclusive effectiveness of application of the polymerasic chain reaction in the purposes of diagnostic. Expediency of application of the molecular-genetic methods for radiating, chemical and extreme effects evaluation.

Communicable Diseases↗

[The current potentials and the role of echocardiography in the diagnosis and surgical treatment of infectious endocarditis].

The authors have analyzed results of examination of 107 patients with infective endocarditis (IE) of the natural (IENV) and artificial valves (IEAV) of the heart. It was found that the revealed ultrasonic symptoms of IE were specific in 97.7% of patients with IENV and in 100% of patients with IEAV. The sensitivity of transthoracal echocardiography was 89.6% in patients with IENV and 65% in patients with IEAV. The intracardiac morphological alterations were found to coincide with the findings of echocardiography in 78.2% of patients with IENV and in 55%--with IEAV. The authors have elaborated an algorithm of the complex diagnostic examination of patients.

Adolescent↗

[Wounds of the heart].

The frequency of wounds of the heart as the cause of lethal outcomes on the battle-field practically has not changed during the recent 50 years and is equal to 80%. At the same time, the danger of such complications as infectious endocarditis has increased. The author's experience with surgical treatment of gunshot wounds of the heart makes 85 cases. Symptoms of intracardiac infection were detected in 74% of the wounded, 52 of them having the septic form. Operations were performed under artificial circulation. They included the extraction of foreign bodies, complex sanitation of the heart chambers and recovery of intracardiac hemodynamics. There were no lethal outcomes in the nearest postoperative period. Success of the treatment depends on terms of delivery of the patient to the hospital, quickness of surgical intervention and adequate intensive therapy.

Adult↗

[The surgical treatment of postinfarct aneurysms of the left ventricle].

Operations for ischemic heart disease complicated by the appearance of postinfarction left ventricular aneurysm were fulfilled on 94 patients. The modified operation after V. Dor used in 55 patients allowed fulfilling interventions on the damaged parts of the interventricular septum excluding the application of foreign patches. Intrahospital lethality was 7.6%.

Adult↗

[Radionuclide study in the diagnosis of infectious foci in heart surgery patients].

The radionuclide investigation was performed 1-3 and 24 hours after injection of a radiopharm preparation and included the single photon emission computed tomography of the heart and scintigraphy of the whole body. Inflammation foci were found on the scans as hyperfixation foci of autoleukocytes labeled with 99mTc-HMPAO (hexamethylpropilene aminooxime). Four patients had abscesses with 0.8-1.5 cm diameter in projection of the aortal and mitral valves of the heart, and in 10 patients there were foci of inflammation and suppuration of extracardiac localization (in the area of the operation wound, anterior mediastinum, frontal sinuses, transverse colon, parietal pleura). The data obtained convincingly speak of high sensitivity and specificity of radionuclide diagnostic methods with the help of labeled elements of the whole blood in recognizing latent inflammatory and suppurative processes in cardiosurgical patients at the pre- and postoperative periods.

Adolescent↗

[The early diagnosis of postoperative infectious complications in heart surgery patients].

Great surgical aggression in operations on the heart and resulting immunodeficiency create prerequisites for the appearance and grave course of infectious complications. The authors have analyzed results of operative treatment of 100 patients with acquired valvular diseases. It has been established that low parameters of the resistance index of organism (RIO) before operation can be estimated as an unfavourable prognostic sign of the development of infectious complications. The RIO dynamics at the postoperative period in many aspects reflects the character of its course. RIO and the indices of the adaptation reaction show the degree of intoxication, make the clinical estimation objective, allow the assessment of efficiency of therapy and correction of medical prescriptions.

Adaptation, Physiological↗

[The Military Medical Academy--the national property of Russia].

Article by the Chief of the Academy has been based on its history of 200 years. One of the oldest establishments of medical education has played a great role in the development of the national and world medicine. Among the Academy graduates of highest merit was N. I. Pirogov, a famous surgeon, who marked a new age in the medical science and education and introduced important innovations in the casualty treatment on the battlefield. He was the first to apply ether anaesthesia and plaster bandage and to have women taking care of the wounded on the theater of operations. Academy graduates S. P. Botkin, G. F. Lang and F. I. Komarov had founded their own schools of therapy. E. N. Pavlovskiĭ developed a study on the focus nativeness of infection and parasite disease process. Every year the Academy scientists implement more than 150 research projects for the government, ministries and different agencies, defend up to 75 theses on 30 specialties, conduct more than 20 national and international conferences, symposiums and meetings. For the last 35 years the Academy has been training medical doctors, scientists and healthcare specialists for 35 countries in Europe, Asia, Africa and Latin America.

History, 18th Century↗

[The principles of guaranteeing the quality of medical care for the wounded and ill].

The author states four main principles of maintenance of quality of the medical care to wounded and patients: a principle of conformity of preparation of the staff to soluble problems is provided by observance of the State educational standards of vocational training--carrying out the professiographic analysis of activity of the surgeons for creation of the models of the experts, perfection of the educational plans and programs; a principle of development of material base with sharp definition of priority spheres of its development for forthcoming year and use of material means for development of economic base of military-medical institutions; a principle of strict observance of modern medical technologies, based on the standards of equipment, outcomes (results of work of the medical institutions), medico-technological and medico-pharmaceutical; a principle of scientific quality management on the basis of estimation of staff-organizational structure of medical units and institutions, treatment-diagnostic technologies (processes) and the results of rendering of the medical care.

Humans↗