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Biomedical subjects

Iu L Shevchenko

Publications and source records attributed to Iu L Shevchenko.

At least 73 records · Page 4Linked to original sources
PubMed1997

[A postinfarct heart aneurysm: its removal or revascularization?].

A conclusion about the hemodynamic significance of aneurysm having the area of more than 30% of the left ventricle surface is made on the basis of an analysis of the pre- and post-operative parameters of the myocardium contractility and hemodynamic indices in 49 patients with postinfarction aneurysm of the left ventricle (main group) and 26 patients with ischemic heart disease without this complication (control group). Formation of the syndrome of chronic insufficiency of blood circulation in hemodynamically insignificant aneurysm results from ischemia of the myocardium, rather than the aneurysm as such. Improvement of blood supply to the myocardium as a result of its revascularization in such patients led to normalization of the left ventricle geometry.

Adult↗
PubMed1996

[The clinical aspects of the aftermath of the accident (based on data from the Military Medical Academy)].

The results of medical examinations of the persons taking part in elimination of consequences of Chernobyl's disaster obtained by the specialists of Military-medical academy allowed to verify the conception of damage action of radiation and nonradiation complex of injury factors, to estimate well-information of stale and new biological indicators of radiation dose, to plan the ways of rescuers rehabilitation during stationary, polyclinic and sanatorium stages of treatment.

Academies and Institutes↗
PubMed1996

[Hospital infection and some aspects of its immunoprophylaxis].

The review deals with the causes and main agents of the hospital infection occurring in surgical units. Special attention is given to the formation of the hospital isolate of the agent. A method of prevention of postoperative infective complications by vaccines prepared of these particular isolated has been proposed.

Bacterial Vaccines↗
PubMed1996

[The organization of the donation of autologous blood and its components in cardiac surgery].

The article analyzes an experience with the organization of autodonation of blood and its components in surgical treatment of 305 patients with congenital and acquired defects and ischemic heart disease. Methods of plasmacytapheresis and cryopreservation used at the terms from 3 days to 12 months before operation allowed storage of the autologous components of blood in 41.2% of the patients having indications for autodonation. In 29.1% of the observations the autotransfusion media were reserved under the outpatient clinic conditions which resulted in shorter terms of treatment at the hospital. The number of unfavorable reactions during the donation in patients did not exceed analogous parameters in regular donors. Autohemotransfusions 3-5 times reduced the volume of transfusions of the allogenic blood components and they were completely avoided in 20.1% of the patients.

Adolescent↗
PubMed1995

[The immunogenetic status of patients with infectious endocarditis].

On the basis of a deep clinico-immunological examination of 23 patients with septic endocarditis it was established that HLA B35 antigen and haplotype A2-B35 are the most probable markers of the genetic predisposition to the development of infective endocarditis. Immune deficiency is accompanied by a decreased content of T-helpers, decreased activity of natural killers and phagocytic activity of granulocytes. A combination of a genetically determined defect of the immune response with a modification of histocompatibility antigens by infective agents, drugs (narcotics, antigens etc.) and other factors are thought to be of pathogenetic significance in the development of infective endocarditis.

Adolescent↗
PubMed1995

[The histocompatibility problem in military blood transfusions].

One of the basic approaches which provides for the increase of immunological safety of hemocomponental therapy is the use of donor-recipient histocompatible blood. The decisive factor in the organism's individuality is HLA-antigen system. Antigen incompatibility of donor's and recipient's tissues in HLA-antigen causes the development of delayed hypersensitivity and sensibilization of the recipient, which provoke a number of complications and posttransfusion reactions. Histocompatibility is the key problem for modern transfusiology and transplantology.

ABO Blood-Group System↗
PubMed1995

[The problem of cytomegalovirus infection in military blood transfusions].

The actuality of a problem of cytomegaloviral infection in military transfusiology is substantiated by the increasing number of immunocompromised recipients, mass use of hemocomponent therapy in prophylaxis and correction of anemia, thrombohemorrhagic and immunodeficient syndromes. Cytomegaloviral infection in the recipients of hemocomponents may have unfavourable consequences, such as the development of mononucleosis, enhanced sensitivity to opportunistic infectious agents as a result of virus-induced immunodepression, graft rejection, risk of the development of oncologic diseases, atherosclerosis, disorders in the processes of reparation and regeneration. In the northwestern part of Russia the cytomegaloviral antigens are disclosed in 65-75% of men, age 18-23. Actual tasks are the following: put into practice cytomegaloviral antigens test for donors, make a wide use of effective leukocytic filters for leukocyte removal from hemotransfusional medium, minimize posttransfusion immunosuppression, determine recipients who need transfusions of hemocomponents prepared from seronegative donors.

Adolescent↗
PubMed1994

[The reform of military medical education and the tasks of the Military Medical Academy in improving personnel training].

The Military Medical Academy is a military educational institution which carries out the primary profile training of physicians for the Armed Services and all types of post-graduation training and advanced training of the scientific-pedagogical and medical specialists. Internship as a first stage of the post-graduation training is intended to improve practical medical training of the graduates of the Russian Military Medical Academy and other medico-military educational institutions by means of their primary specialization in one of the clinical or profile branches of medicine. The reforming of the post-graduation training rest system in the Military Medical Academy aims at its further development and putting specialists' training system into accordance with the Armed Forces reorganizations. This will make it possible to ensure high professional qualification of military doctors at the level of national and international standards.

Education, Medical, Continuing↗
PubMed1992

[Cardiac abscesses].

The paper analyzes the experience in treating 75 patients with cardiac abscesses of various sites. Abscesses complicated the natural history of infectious endocarditis in all patients. The clinical features of cardiac abscesses are shown to be related to the stage of the destructive process. Echocardiography, follow-up analysis of ECH, PhCG and overall clinical data are demonstrated to play a role in their diagnosis. The paper discusses the specific features of surgical intervention into the heart if abscesses are present. Out of 75 patients who have been operated on for abscessing infectious endocarditis, 53 have had an operation and survived.

Abscess↗