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Biomedical subjects

Iu V Anshelevich

Publications and source records attributed to Iu V Anshelevich.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Determination of the sensitivity of beta adrenergic receptors in patients with myocardial infarction].

The effect of propranolol on hypotonic erythrocyte hemolysis was investigated in normal subjects and coronary patients. In the latter, erythrocytes were shown to have much smaller osmotic stability as compared to the former. Propranolol's in vitro antihemolyzing effect is more pronounced in patients with acute myocardial infarction and angina pectoris as compared to normal subjects. antihemolyzing effect of propranolol is reduced if it is preceded by the administration of beta-adrenoblockers in myocardial infarction. It is suggested that propranolol's antihemolyzing effect be used for the assessment of beta-adrenoreceptor function.

Adult↗
PubMed1982

[Complications after intravenous administration of anti-arrhythmia agents].

The frequency and nature of side-effects are analysed in 945 patients subjected to 1205 intravenous infusions of various antiarrhythmic agents. The most common side-effects of novocainamide, isoptin, obsidan, lidocain and trimecain are arterial hypotension and shock, while conductivity disorders, asystole (novocainamide, isoptin), bradycardia, acute heart failure (obsidan) are less frequent. Rapid strophanthin saturation in patients with supraventricular paroxysmal tachyarrhythmias can result in ventricular extrasystole, and the use of phenylephrine hydrochloride can produce an excessive hypertensive response. The occurrence of side-effects can be reduced considerably if antiarrhythmic agents are employed on a correct methodological basis, with adequate infusion rate observed, the first dose correctly chosen, potassium preparations added to the treatment, etc.

Adult↗
PubMed1980

[Comparative effectiveness of treating paroxysms of atrial fibrillation and flutter].

Single intravenous injection of drugs arrests 1/3 of atrial fibrillation paroxysms and only 1/7 of atrial flutter paroxysms. According to the frequency of the arresting effect in paroxysms of atrial fibrillation, isoptin, a combination of procaine hydrochloride with strophanthin, and giluritmal take first place. In paroxysms of atrial flutter, isoptin produces the best effect. Combined antiarrhythmic therapy with several drugs results in the arrest of about 50% of tachyarrhythmia paroxysms in a few hours to 10 days. Emergency indications for the application of electric-pulse therapy are noted among 7.9% of patients with fibrillation and among 6.6% of those with flutter of the atria.

Adult↗
PubMed1978

[Use of clofelin for arresting hypertensive crises].

The authors gave clophelin by intravenous (0.1 g) or intramuscular (0.1--0.15 mg) injections to 75 patients who were in a state of hypertensive crisis. In 67 patients (89--4%) the crisis was successfully arrested. In most patients maximum hypotensive effect occurred 10--20 minutes after intravenous injection and 20--30 minutes after intramuscular administration. Tolerance to a single injection of the drug was good. In some cases there was a marked additional fall of arterial pressure in the orthostatic position, a sensation of dryness in the mouth, weakness and mild somnolence.

Adult↗