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J C Chaput

Publications and source records attributed to J C Chaput.

At least 109 records · Page 6Linked to original sources

[Chronic alcoholic pancreatitis: relation of pain to withdrawal and pancreatic surgery].

A group of 73 patients suffering from painful alcoholic, chronic pancreatitis, hospitalized from 1971 to 1981, has been analyzed retrospectively. The aim was to assess the effects of alcohol withdrawal and pancreatic surgery on the course of pancreatic pain. The mean number of years during which the patients complained of pain was 3.5 +/- 0.5 (m +/- SEM). At the end of follow-up, 70 p. 100 of the patients did no longer suffer, alcohol withdrawal was obtained in 45 p. 100 and surgery had been performed in 41 p. 100. Continued alcohol abuse did not prevent pain relief: 60 p. 100 of patients continuing to drink at the end of follow-up, did not suffer any longer. One year after pancreatic surgery, pain relief was more frequent, if alcohol abstinence had been obtained before surgery (p less than 0.01). Among the 53 patients followed up to 5 years after the start of pain: a) the cumulative actuarial probability of disappearance of pain was 17 p. 100 at 2 years, 52 p. 100 at 5 years, 62 p. 100 at 8 years after the start of pain. Alcohol abstinence and surgery were observed during the first five years of pain; b) the mean number of years of pain was lower among the patients who became abstinent early (less than 4 years after the beginning of pain) than among those who did not (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Alcoholism↗

[Analysis of factors related to length of stay in the hospital in a hepato-gastroenterology unit].

Because hospital length of stay is the most important determinant of cost of hospitalization, this study was performed to analyse factors contributing to hospital length of stay in an hepato-gastroenterology unit. Prospectively collected computerized files of the first 750 patients admitted in 1982 were analyzed according to primary diagnosis, age and sex. Ten primary diagnosis categories were established. By multivariate analysis, alcoholic liver disease and the non-digestive diseases correlated best with the hospital length of stay. Variables most predictive of an hospital length of stay greater than 14 days were diagnosis of alcoholic liver disease, patient age and diagnosis of non-alcoholic cirrhosis. Analyses of this kind are essential in making policy decisions regarding hospital cost reduction.

Adult↗

Relations between effectiveness of a diagnostic test, prevalence of the disease, and percentages of uninterpretable results. An example in the diagnosis of jaundice.

The relations between effectiveness, the percentages of uninterpretable results of a test, and the prevalence of the disease are studied in the example of the diagnosis of jaundice. Ten hepatologists and ten hepatobiliary surgeons were interviewed, and nineteen articles were reviewed. Accuracies of ultrasonography, endoscopic retrograde cholangiography, and transhepatic cholangiography, as well as of three strategies combining these tests, were ranked by hepatologists in an order that differed from chance, and by surgeons in an order that did not differ from chance. Analyses of published data, taking into account the percentages of uninterpretable results, showed that for a high prevalence of extrahepatic cholestasis, as in jaundiced patients seen by surgeons, there is no significant difference between the respective effectiveness of each test or strategy. We concluded that effectiveness must take into account the percentages of uninterpretable results and must be expressed as a function of prevalence.

Cholangiography↗

[Hepatology in 1981].

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Chemical and Drug Induced Liver Injury↗