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Biomedical subjects

J C Folk

Publications and source records attributed to J C Folk.

100 records · Page 6Linked to original sources
PubMed1983

Syphilitic neuroretinitis.

Four patients (three men, 32, 43, and 53 years old, and one 37-year-old woman) with syphilitic neuroretinitis had cerebrospinal fluid evidence of neurosyphilis. Therapy failed in one patient given penicillin G benzathine intramuscularly and it may have failed in a second patient. Another treatment failure occurred in a patient given tetracycline orally. Intramuscular penicillin G benzathine or intramuscular penicillin G procaine in doses of less than 2.4 million units/day does not produce spirocheticidal drug levels in the cerebrospinal fluid. All four patients improved after high-dose treatment with aqueous penicillin G.

Administration, Oral↗
PubMed1982

Pattern dystrophy of the retinal pigment epithelium.

The pattern dystrophies are a group of hereditary macular dystrophies characterized by lesions of the retinal pigment epithelium (RPE) arranged in various patterns of dots, lines, and branched figures. This report of two pedigrees expands the clinical spectrum. The onset is usually in the second and third decade, there is great variation in fundus appearance, vision may be severely affected, the EOG is not always abnormal, and the fundus lesions change with time. The lesions resemble those of Best's vitelliform degeneration and fundus flavimaculatus, and, possibly, also represent abnormal lipofuscin accumulation within degenerating retinal pigment epithelial cells.

Adolescent↗
PubMed1982

Bilateral phakic retinal detachment.

Ninety-nine (11.6%) of 850 phakic retinal detachment patients had bilateral detachments. The incidence of bilaterality was greater in nontraumatic detachments (13.4%) than traumatic detachments (3.8%). Patients were divided into two refractive classes: (1) myopic, containing refractive errors of -2.50 diopters or more, and (2) nonmyopic, containing all other refractive errors. The rate of bilaterality in nontraumatic detachments varied with refractive class and lattice degeneration: nonmyopic without lattice (8.1%), nonmyopic with lattice (14.2%), myopic without lattice (16.3%), and myopic with lattice (24.6%). Mean age in years at onset of the initial detachment varied with refractive class and lattice degeneration: nonmyopic without lattice (59.1), nonmyopic with lattice (55.8), myopic without lattice (49.2), and myopic with lattice (28.2). Lattice degeneration reduced the interval between detachments. Annual risks of fellow eye detachments were calculated for four groups: nonmyopic without lattice (0.12%), nonmyopic with lattice (0.95%), myopic without lattice (1.3%), and myopic with lattice (0.98%).

Eye Injuries↗
PubMed1982

Diabetic retinopathy.

It is hoped that this article has given the family physician an understanding of diabetic retinopathy and the recent advances in its treatment. It is crucial that both the family physician and an ophthalmologist follow diabetic patients closely, especially once they develop preproliferative or proliferative retinopathy. Too many patients lose their sight because they are first seen for treatment too late in the course of their disease. This is indeed a tragedy because laser treatment is effective in most patients.

Adult↗
PubMed1982

Senile macular degeneration.

Senile macular degeneration is a common disease, especially in the elderly population, but fortunately a national multicenter study has recently proved that treatment by argon laser photocoagulation is efficacious in many of these patients if the diagnosis is made promptly. Family physicians play an important role in diagnosing treatable forms of the disease quickly and in educating their elderly patients about the symptoms of this condition.

Aged↗
PubMed1981

Coats' disease in a patient with Cornelia de Lange syndrome.

A 16-month-old boy had the mental and physical retardation, low-pitched cry, phocomelia with syndactyly, hirsutism, low-set ears, bushy eyebrows, elongated eyelashes, blepharoptosis, and strabismus characteristic of Cornelia de Lange syndrome along with ophthalmoscopic findings characteristic of Coats' disease. Cryotherapy made the abnormal telangiectatic vessels less prominent, but macular scarring produced poor visual acuity. Occlusion therapy was unsuccessful.

Amblyopia↗