PubMed Health⌕ Search

Biomedical subjects

J C Sharma

Publications and source records attributed to J C Sharma.

At least 37 records · Page 2Linked to original sources
PubMed1996

Immunoglobulin profile in mycetoma.

Serum samples obtained from 25 patients of mycetoma caused by Madurella mycetomi in 18, Streptomyces somaliensis in 5, Streptomyces madurae and streptomyces palletierii from 1 each and also from 25 healthy controls were evaluated for immunoglobulins IgG, IgM and IgA by radial immunodiffusion method using tripartigen plates. All the three classes of immunoglobulins showed increased concentration in cases of mycetoma by M. mycetomi and S. pelletierii. The raised levels of IgG and IgM in cases of mycetoma caused by S. madurae and S. somaliensis where bones were involved, were not statistically significant. IgA was consistently high in all cases of mycetoma irrespective of causative agent and tissue involved. These alterations may possibly reflect relatively poor IgG and IgM response in individuals with extension of mycetoma lesion to bones.

Antibodies, Bacterial↗
PubMed1995

Lateral condylar fractures of the humerus in children: fixation with partially threaded 4.0-mm AO cancellous screws.

Thirty-seven children with fresh, displaced (more than 2 mm in any direction) fractures of the lateral condyle of the humerus were treated by open reduction and internal fixation with a partially threaded 4.0-mm diameter AO lag screw. They were reviewed at a mean follow-up of 4.8 years. Painless, full-elbow movements were obtained in 36 cases. Delayed union, with loss of 10 degrees of elbow motion, was observed in one case (2.72%). Radiologically, less than 4 degrees of varus deviation, compared with the contralateral side, was found in four cases (10.8%). Mild fishtailing was observed in three cases (8.18%). Nonunion, avascular necrosis or clinically significant premature epiphysial fusion was not observed. Elbow function was excellent, irrespective of minor radiologic abnormalities.

Bone Screws↗
PubMed1993

Comminuted femoral shaft fractures treated by closed intramedullary nailing and functional cast bracing.

Eighty-one patients with comminuted femoral shaft fractures were treated by closed unlocked Küntscher nailing and functional cast bracing for 1 to 4 weeks postoperatively depending on the degree of comminution. The mean follow-up period was 27.6 months. The average time required for fracture healing was 14 weeks. There was one delayed union. One fracture united with more than 10 degrees of rotational malalignment; shortening of more than 1 cm was present in four cases. Two patients had more than 20 degrees of limitation of hip and knee movement.

Adolescent↗
PubMed1992

Management of childhood femoral neck fractures.

Forty-three children with displaced transcervical femoral fractures were reviewed at a mean follow-up of 7.2 years and results were assessed using Ratliff's criteria. Of 22 patients treated by internal fixation alone, 10 had good, 6 had fair and 6 had poor results. The results in 21 children treated by internal fixation along with primary transverse intertrochanteric undisplaced osteotomy were: 14 good, 5 fair and 2 poor, but none improved to a statistically significant level (P = 0.139). However, the osteotomy improved the fracture union significantly and no delayed union or non-union was noted in this group (P = 0.05). There were no complications related to the osteotomy itself.

Adolescent↗
PubMed1990

Tibial condylar fractures treated with traction and early mobilisation (report on study of 75 cases).

Seventy-five cases of tibial condylar fractures irrespective of type of fractures were treated on a purely conservative line of management, consisting of traction and early mobilisation. The follow-up ranged from 6 months to 10 years; 67 cases had satisfactory results. Causes of unsatisfactory results were stiff knee, flexion deformity, osteo-arthritis and ligamentous instability.

Adult↗
PubMed1989

Ipsilateral supracondylar fracture of humerus and forearm bones in children.

A total of 34 children with ipsilateral supracondylar fractures of the humerus and forearm were studied over an 8-year period. Of these, 19 patients had fractures of the distal quarter of the forearm bones while eight patients had a distal radial epiphyseal injury. Five of the patients had undisplaced supracondylar fractures. One patient had an anterior supracondylar fracture. All forearm fractures were treated by closed reduction. Nine displaced supracondylar fractures which could not be reduced by closed manipulation were treated by olecranon pin traction in two cases and by percutaneous pinning in seven cases. Excellent or good results were found in 29 children after an average follow-up of 3.8 years.

Adolescent↗
PubMed1988

Genetic markers in the Hindu and Muslim Gujjars of Northwestern India.

A comparative study of serogenetic markers was carried out among the Hindu and Muslim Gujjars from Northwestern India. From each isolate of Gujjars, 200 adult couples were examined for the A1A2BO and Rhesus blood groups, ABH secretion, the serum proteins haptoglobins, transferrins, and albumins, and 200 male subjects were examined for glucose-6-phosphate dehydrogenase enzyme deficiency. The study showed that the Muslim Gujjars differ significantly from their counterpart, the Hindu Gujjars. The differentiation that has occurred among the Muslim Gujjars may be attributed to their geographical dispersal in diverse habitats, the inflow of genes from Islamic invaders as well as non-Islamic surrounding populations, the inbreeding effect, and the comparative breeding isolation. The genetic affinities of the Hindu Gujjars with the Jats and Rajputs provide strong evidence for their common ethnic origin and probably their recent fissioning owing to biosocial practices and occupational patterns. The computed genetic distance matrix shows diversity of Ahirs from all the concerned population groups.

ABO Blood-Group System↗
PubMed1988

Causes of ataxia in patients attending a falls laboratory.

The relationship of a range of clinical variables to balance was investigated in a group of 121 elderly patients giving a history of falls. Information collected included a clinical history and physical examination, and an evaluation of position sense, vibration sense and vestibular function. Postural changes in blood pressure were measured on a tilt-table, and sway was quantified on an ataxiameter. There was a statistically significant relationship between leg power, visual acuity, posture sense and mental function and sway, and a weaker positive association between a variety of other factors and sway. When factors showing a positive association with sway were used to construct a 'pathology' scene for each patient, it emerged that there was a statistically significant correlation between scores and ataxiameter readings. This suggests that, in the elderly, ataxia is usually the result of multiple factors.

Accidental Falls↗
PubMed1988

Continuous suction and intermittent irrigation for septic coxitis.

This prospective study was undertaken on 42 children with septic arthritis of the hip diagnosed within 5 days of onset of symptoms. The mode of treatment used was continuous catheter suction and intermittent saline irrigation of the hip joint together with parenteral antibiotics. All but 4 children responded to this treatment; 2 of these were less than 3 years old. We conclude that continuous suction-irrigation is effective in children older than 3 years very early in the course of the disease; the majority need not undergo arthrotomy.

Adolescent↗
PubMed1986

Dermatoglyphic studies among the two breeding isolates of Gujjars of northwestern India.

Dermatoglyphic studies among two breeding isolates of Gujjars (200 individuals from each population) from northwestern India have been carried out. The distribution of phenotypic frequencies of dermatoglyphic features among the Hindu and Muslim Gujjars provides strong evidence that these populations have become distinct in the course of their history. This could have occurred due to the inflow of genes from Muslim invaders and surrounding populations or from the effects of inbreeding and biosocial and geographical isolation of the Muslim Gujjars from their counterpart, the Hindu Gujjars. However, the frequency distribution of dermatoglyphics of the Hindu Gujjars resembles those of the Rajputs, Jats, and Ahirs, suggesting an infrequent inflow of genes from neighboring populations and probably their recent isolation. Sexual dimorphism for dermatoglyphics has also been observed in both Hindu and Muslim Gujjar populations.

Demography↗
PubMed1985

Mycetoma caused by Aspergillus nidulans in India.

The first case of mycetoma caused by Aspergillus nidulans has been described from India in a young farmer of Jaisalmer situated in the Thar desert of Western Rajasthan, India. The diagnosis was confirmed by histopathological and mycological studies.

Adult↗
PubMed1984

Estimates of genetic variance for some selected morphometric characters: a twin study.

Results on genetic variability in some of the morphometric characters on head and face, body girths and skin folds, based on 45 MZ and 67 like-sex DZ twin pairs, are presented. The data were subjected to a method which eliminated possible biases in the estimated genetic variances that could result from heterogeneity of total variances between zygosities of the 17 head and face measurements, heterogeneity was observed for only bizygomatic diameter. Head breadth means differed between MZ and DZ twins, indicating bias in the trait's genetic variance analysis. The results indicated a significant genetic component in these morphometric traits. For 11 girth and skinfold measurements, the t'-test based on hierarchical structure of twin data, also failed to reveal any appreciable difference between the mean values of MZ and DZ twins. Heterogeneity of total variance between zygosities was observed for three skinfold measurements, ie, biceps, triceps and suprailiac. The girth measurements, however, did not reveal any heterogeneity of total variances between the zygosities. The estimates of genetic variance revealed stronger genetic component for the girths than for the skinfolds.

Anthropometry↗
PubMed1984

Value of serum ferritin as an index of iron deficiency in elderly anaemic patients.

Serum ferritin was correlated with bone marrow iron stores in 35 elderly anaemic patients. All 19 patients with low serum ferritin had iron deficiency as assessed on bone marrow examination, whereas six patients with low or absent bone marrow iron stores had serum ferritin within normal range. A low serum ferritin invariably indicates iron deficiency and has a better correlation than low serum iron. Serum ferritin should be included in the initial investigation of the anaemic elderly.

Aged↗