PubMed Health⌕ Search

Biomedical subjects

J D Wright

Publications and source records attributed to J D Wright.

97 records · Page 6Linked to original sources
PubMedDate not supplied

Visual complaints from healthy children.

It is common for healthy children with specific visual complaints to be seen for eye examinations. After a complete eye examination has ruled out pathologic conditions as the cause of these complaints, it is appropriate for the clinician to explore the possibility that normal entoptic or physiologic visual phenomena might have provoked the child's report of vision problems. Some of these normal visual experiences are frequent causes of children's complaints of vision problems, such as physiologic diplopia, relaxation of the near synkinesis during reading, and vitreous body floaters. Some complaints are common, even though the underlying entoptic or physiologic phenomenon may be speculative or obscure, such as the report that objects look bigger or smaller than they actually are. When the clinician encounters such situations, the parents and the child will be much more satisfied by an explanation of the normal system anatomy and physiology than by the simple reassurance that everything is all right.

Accommodation, Ocular↗
PubMedDate not supplied

Lateral collateral ligament avulsion of the humeroradial joint in a horse.

This report describes traumatic avulsion of the lateral collateral ligament of the humeroradial joint in a horse. The history and diagnostic procedures are included with relevant radiographs and ultrasonographs. The poor prognosis associated with this injury is due to degenerative joint disease.

Animals↗
PubMedDate not supplied

Conjunctival biopsy in patients with Kawasaki disease.

Kawasaki disease (KD) is an acute vasculitis of infants and young children that is associated with bilateral nonexudative conjunctivitis during the acute illness. Epidemiologic evidence has suggested an infectious cause but the etiology of KD remains unknown. We examined conjunctival biopsy specimens from seven patients with typical KD to characterize the pathologic changes during the acute disease. Light microscopic examination revealed nonspecific, mild inflammatory changes that included vascular dilatation, infiltration with scattered lymphocytes, increased numbers of plasma cells in the conjunctival stroma, and increased prominence of goblet cells in the epithelium. No pathogens were identified by special stains for bacteria and rickettsiae, nor were viral particles seen by electron microscopy. We conclude that the conjunctivitis of acute KD is characterized by vascular dilatation with a mild mononuclear cell response with no pathognomonic features. The conjunctiva can be readily sampled in these patients and biopsy may prove useful in selected patients to exclude other clinical entities in the differential diagnosis.

Acute Disease↗
PubMedDate not supplied

Congenital glaucoma unresponsive to conventional therapy: a clinicopathological case presentation.

A clinicopathological case report of a black male with congenital glaucoma is presented. The child died at age three months of the Sudden Infant Death Syndrome. The clinical course was characterized by persistent corneal clouding and elevated intraocular pressure in spite of vigorous medical and surgical therapy. Histopathological findings included corneal enlargement, marked hypoplasia of the canal of Schlemm, poorly developed scleral spur, insertion of the ciliary musculature directly into the trabecular meshwork anterior to the scleral spur, and anterior displacement of the iris root. There was also anomalous dispersion of the sphincter muscle of the iris from the pupillary margin almost to the iris root, and attachment of some ciliary processes to the posterior surface of the iris. A poor clinical response to conventional glaucoma therapy, including trabeculotomy, goniotomy, trabeculectomy and medical therapy, supports the belief that the marked hypoplasia of Schlemm's canal was a major factor contributing to the elevated intraocular pressure. Furthermore, the multiplicity of abnormalities of anterior chamber angle structures suggests that some cases of congenital glaucoma may result from an early and extensive disorder in the formation of anterior segment tissues.

Autopsy↗