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Biomedical subjects

J Di Canzio

Publications and source records attributed to J Di Canzio.

5 recordsLinked to original sources
PubMed1999

Anterior cruciate ligament reconstructive surgery in adolescent soccer and basketball players.

OBJECTIVE: To evaluate trends in the frequency of anterior cruciate ligament (ACL) tears among adolescent soccer and basketball players resulting in reconstructive surgery, and to assess differences between female and male adolescent athletes. DESIGN: A retrospective review of ACL reconstructive surgeries performed from 1992 through 1997 and annual statewide participation rates obtained from the National Federation of State High School Associations. SETTING: Children's Hospital, Boston, Massachusetts, U.S.A. PATIENTS: Adolescent athletes 13 to 19 years of age (78 girls, 31 boys) admitted for ACL reconstruction due to soccer or basketball injuries. MAIN OUTCOME MEASURES: Number of ACL reconstructive surgeries and number of Massachusetts participants in high school soccer and basketball. RESULTS: A total of 69 soccer (49 girls, 20 males) and 40 basketball (29 girls, 11 males) players underwent ACL reconstruction. A greater proportion of girls underwent ACL surgery in both sports. The frequency increased over time for both sexes in both sports. Soccer-related surgeries increased at a faster rate among girls than boys. Basketball-related surgeries increased at a similar rate for both sexes, although in any given year more surgeries were performed on girls. CONCLUSION: The frequency of ACL surgery at our institution has increased among high school soccer and basketball players in a manner consistent with trends in sports participation. In our study, ACL surgery was more common among girls than boys.

Adolescent↗
PubMed1998

A statistically defined endpoint titer determination method for immunoassays.

Results of immunoassays for which no positive standards are available are often expressed as endpoint titers. The endpoint titer is defined as the reciprocal of the highest analyte dilution that gives a reading above the cutoff. Unfortunately, there is no generally accepted rule for the determination of these cutoff values. In enzyme-linked immunosorbent assays (ELISA) a value two or three times the mean background or negative control reading is sometimes used. Other investigators set the cutoff arbitrarily at a certain absorbance value. These procedures do not provide statistically meaningful information about the risk of overtitration or false low titers. We have solved this problem by devising a practical method for establishing a statistically valid cutoff. The procedure involves calculating the upper prediction limit using the Student t-distribution. The mathematical formula which defines the upper prediction limit is expressed as the standard deviation multiplied by a factor which is based on the number of negative controls and the confidence level (1 - alpha). Appropriate factors are provided for 2 to 30 negative controls and for confidence levels ranging from 95% to 99.9%. Our new method is more reliable than other nonstatistical procedures yet does not require sophisticated computation. It can be applied to a variety of immunoassays provided that negative controls are available.

Enzyme-Linked Immunosorbent Assay↗
PubMed1998

The effect of temperature changes on the dimensional stability of polyvinyl siloxane and polyether impression materials.

STATEMENT OF PROBLEM: Dental impressions are commonly mailed to remote dental laboratories and can be subjected to extreme temperature changes; however, the effects of these temperature changes on the accuracy of elastomeric impression materials are unknown. PURPOSE: This study evaluated the dimensional changes of polyether and polyvinyl siloxane impression materials as a function of storage temperature. MATERIAL AND METHODS: A total of 144 impressions were made of a stainless steel die similar to ADA Specification No. 19. Half of the impressions were made in perforated custom trays and the other half in solid trays. Measurements of the vertical and horizontal lines on the impressions were made at 10 minutes, 1 hour, 24 hours, and 26 hours, and storage temperatures ranged from 4 degrees C to 40 degrees C. RESULTS: Changes in storage temperature had a statistically significant effect on the dimensional stability of the horizontal and vertical lines. However, overall dimensional changes were extremely small. CONCLUSIONS: Storing both impression materials at 4 degrees C for 24 hours and then allowing the impressions to reach room temperature resulted in a slightly expanded impression that partially compensated for the contraction that occurred from polymerization shrinkage. Similar results occurred for polyether material only, when stored at 40 degrees C.

Analysis of Variance↗
PubMedDate not supplied

Normal ranges of scapholunate distance in children 6 to 14 years old.

SUMMARY: The purpose of this study was to determine the normal ranges of scapholunate distance (SLD) applicable to children. Bone age radiographs of 85 children (36 boys, 49 girls) 6 to 14 years of age were used to establish the normal ranges. Repeated-measures analysis of variance revealed significant age and gender differences. Therefore, linear regression was used to determine normal SLD ranges separately for girls and boys based on chronologic age and bone age. SLD normal ranges were similar for chronologic age and bone age. Interobserver and intraobserver agreement was excellent. There was no significant age by gender interaction found, indicating that although boys had significantly longer distances than girls, both showed a similar rate of decreasing SLD distance with age. These results provide age-and gender-based normal ranges of SLD in young children. These results may be useful in assessing traumatic soft tissue injuries about the pediatric wrist. Of note, only three girls and two boys (all 12 years or older) met the adult criterion of normal SLD of < or = 2 mm.

Adolescent↗