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Biomedical subjects

J E Hoopes

Publications and source records attributed to J E Hoopes.

At least 55 records · Page 3Linked to original sources

Health manpower legislation.

In response to the desires of Congress, medical schools dramatically enhanced their ability to perform biomedical research and to educate health professions personnel. Initially, Congress viewed health professionals as a national resource in terms of being willing to subsidize their education. Congress continues to view the health professions as a national resource, but the philosophy of Congress has become substantially modified: Congress is unwilling to subsidize the education of physicians, but perceives that it must regulate their specialty and geographic distribution. Medical students and medical schools have, in a major sense, been left "holding the bag." A cogent argument can be offered that the natural history of health-care evolution has been confused by excessive meddling with the system. Additional legislatively induced confusion should not be imposed, at least until the results of the previous meddling have been observed. Unfortunately, the foregoing presentation raises considerably more questions than it answers: Medical schools: What will be the source(s) of financial support? Medical students: What will be the impact of tuition indebtedness? Practicing physicians: What will be the result(s) of severe competition? Health professions educational institutions must address fundamental issues concerning their financial survival. That is, will they accept the carrot-and-stick philosophy and pursue federal funding? or will they seek financial independence toward the goal of assuming responsibility for their own destiny? The philosophy of federal funding "without strings attached" does not exist.

Education, Medical↗

Electrical burns of the oral commissure: treatment results and principles of reconstruction.

Reconstruction of the average oral commissure electrical burn deformity yields good results when performed as a delayed procedure. Our preferred technique utilizes available vermilion for reconstruction of the lower lip by a rotation flap, and a mucosal advancement flap for reconstruction of the upper lip. Since using this procedure, we have not had a recurrent contracture requiring reoperation.

Burns, Electric↗

Enzymatic responses to skin flap elevation following a delay procedure.

Alterations in enzyme activities of glucose metabolism were determined in the distal portion of the skin flaps of guinea pigs elevated following 3, 7, 14, or 21 days of the delay period. Hexokinase, pyruvate kinase, lactate dehydrogenase, and glucose 6-phosphate dehydrogenase activities were increased during the delay period, whereas isocitrate and malate dehydrogenases exhibited little alteration. Increases in glycolytic enzyme activities observed during the delay procedure were diminished in the flaps elevated during initial 3 days of the delay period, but were maintained or increased further in the flaps elevated at 7 to 21 days. Despite high levels of enzyme activities during the early period of the delay, the flaps elevated during this period exhibited partial necrosis with a low glucose level and decreased enzyme activities. It is concluded that tissue glucose level and its utilization are crucial factors for flap survival.

Alcohol Oxidoreductases↗

Breast reconstruction after mastectomy.

Recreation of normal breast anatomy and restoration of female body image after mastectomy for cancer are the goals of the reconstructive surgeon. Several recently refined techniques in plastic and reconstructive surgery have made the task of reforming the female breast easier while producing more predictable results. A blending of ideas has begun between the general surgeon performing the mastectomy and the plastic surgeon reconstructing the breast. Breast reconstruction in selection patients has become an accepted part of rehabilitation. It is the purpose of this paper to address the problems of breast cancer and patient selection for reconstruction and to outline the surgical techniques.

Adult↗

Blunt chest trauma: evaluation of the augmented breast.

Breast augmentation is being done increasingly, not only for women who consider their breasts too small but also for those with breast asymmetry, and post-mastectomy patients with reconstruction. It appears inevitable that traumatologists will have to evaluate injury to an augmented breast in a patient who has sustained blunt chest trauma. This paper discusses the differential diagnosis and treatment of implant rupture, hematoma, and spherical capsular contracture as a result of trauma.

Accidents, Traffic↗

Management of compound injuries of the lower extremity.

The reconstructive surgeon experienced in the use of rotated or free muscle and myocutaneous flaps, skilled in microvascular surgery, and interested in lower extremity trauma, may favorably alter the course of management of these historically difficult problems. It can be of great advantage to the patient if this surgeon is involved in the primary evaluation, so that all initial therapy can be performed with the future reconstructive goals in mind.

Adolescent↗

Pilar tumors.

We present 5 cases of pilar tumor, and we review the controversy over whether this tumor has a malignant potential. We feel the correct treatment is excision deep to galea, with a one to two cm margin of normal scalp. Presented with a pathology report of "pilar tumor" on a "shelled out" or ruptured sebaceous cyst, we feel the correct treatment is complete excision of the previous scar, going deep to the galea and taking a one to two cm margin of surrounding normal scalp.

Aged↗

Metabolic adaptations in delayed skin flaps. Glucose utilization and hexokinase activity.

The distribution of glucose and hexokinase activity was determined in the epithelial tissue of delayed bipedicled skin flaps in guinea pigs. The periods of "delay" were 1, 3, 7, 14, or 21 days. The flap survival was maximal (100% of the flap) when the flap elevation was performed either 7 or 14 days following the "delay" procedure. When the flap elevation was performed 1, 3, or 21 days following the "delay" procedure, the result was partial necrosis. A differential distribution of epithelial glucose was found within the bipedicled flaps. The lowest glucose level (30% of normal) was at a distance of 2 to 3.5 cm from the end of the caudal pedicle during the first day after the "delay" procedure. This decreased glucose content recovered toward normal levels during the later part of the "delay" period. The bipedicled flaps exhibited increased hexokinase activity during the 3-week period of the "delay," and the responses of hexokinase activity and tissue glucose levels to the "delay" procedure were reciprocal in the caudal half of the flaps.

Animals↗