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Biomedical subjects

J E Hoopes

Publications and source records attributed to J E Hoopes.

At least 73 records · Page 4Linked to original sources

Reduction mammaplasty: a technique to achieve the conical breast.

Conceptualization of the problem in reduction of the large breast is defined. A technique for reduction mammaplasty is presented based on: (1) the Wise-type pattern, (2) wide undermining of skin flaps with definitive sculpting of the breast parenchyma, and (3) utilization of hypotensive anesthesia. A series of 63 patients is presented in which this technique was utilized.

Adolescent↗

Skin flap necrosis in guinea pigs: limitation of glucose supply and accumulation of lactate.

The distribution of glucose and lactate within skin flaps was determined in full-thickness guinea pig skin (excluding the panniculus carnosus). The distal end of the flaps had a low glucose content (less than 50 percent of normal) but high lactate level (2 to 3 times normal) during the 3 days after flap elevation. Progressively decreasing gradients of glucose content, and increasing gradients of lactate content, were demonstrated from the mid-region to the distal end of the flaps at 3 hours postoperatively. The decrease in glucose and the accumulation of lactate may play a significant role in skin necrosis.

Animals↗

Subcutaneous mastectomy: a plea for conservatism.

The course after subcutaneous mastectomy is not without problems and the esthetic results, even in the absence of complications, are frequently disappointing. The role of subcutaneous mastectomy in the management of breast pathology remains uncertain at this time.

Adult↗

High tension electrical injury of the upper extremity.

A group of 18 patients received a high tension electrical injury of the upper extremity. The over-all results were dismal. Opportunity for improvement appears to lie in a regimen of rapid and complete removal of devitalized skin and muscle, avoidance of contamination and desication and the early provision of blood supply and wound coverage with pedicled flap coverage.

Arm Injuries↗

Enzymes of glucose metabolism in palmar fascia and Dupuytren's contracture.

Several enzymes participating in glucose metabolism and some of the acid hydrolases were assayed in palmar fascia and Dupuytren's contracture with fluorometric microanalytical methods. The enzyme activities of glucose metabolism were lower in normal palmar fascia than in dermis. The fascia of Dupuytren's contracture exhibited a general increase in the enzyme activities of glucose catabolism. Little alteration was found in alanine aminotransferase and UDP-glucose dehydrogenase activity in the lesion. Lysosomal hydrolytic enzyme activities were increased five to ten times in Dupuytren's tissue. The dermis overlying Dupuytren's contracture exhibited an increase in the enzyme activities of glucose catabolism, but to a lesser degree than did the fascia of the lesion. The epidermis of involved palmar skin displayed normal enzyme activities.

Acid Phosphatase↗

The Charles procedure for primary lymphedema. Long-term clinical results.

The best treatment for primary lymphedema has been a controversial point, because of the lack of clinical documentation of really long-term successful results after any therapy. We report the long-term results in 10 patients (12 extremities) after the Charles procedure. These patients were evaluated at an average period of 10 1/2 years following the surgery (4 of these extremities were examined 20 or more years following the surgery). All of them demonstrated excellent functional results; none demonstrated a recurrence of the lymphedema. We consider the Charles procedure to be the operation of choice in patients with primary lymphedema which is not responsive to conservative therapy.

Adolescent↗

Velopharyngeal insufficiency in hemifacial microsomia.

One-third of a group of 18 patients with hemifacial microsomia demonstrated velopharyngeal insufficiency of a significant degree. The ones with velopharyngeal insufficiency tended to have more severe soft tissue and skeletal deformities of the maxillary-malar complex, associated with a total unilateral palatal paralysis. Cinefluoroscopy was not helpful in diagnosing the velopharyngeal insufficiency. Fiberoptic nasopharyngoscopy, in contrast, proved to be an excellent diagnostic tool. We suggest that patients with hemifacial microsomia have a careful, periodic speech evaluation as an essential part of their overall management.

Endoscopy↗