PubMed Health⌕ Search

Biomedical subjects

J F Hecker

Publications and source records attributed to J F Hecker.

At least 37 records · Page 2Linked to original sources
PubMed1979

Thrombus formation on catheters in new born lambs.

Catheters were inserted into the aorta and inferior vena cava of newborn lambs by cutdown on the femoral vessels and directly into the umbilical vein. The lambs were killed after six days and the amounts of thrombus surrounding the cathethers were measured. Most catheters inserted into the umbilical vein looped within the liver and only a few passed directly into the portal vein or through the ductus venosus into the vena cava. On different types of catheters inserted via the femoral artery or femoral vein, there were significant differences both in the proportion with thrombus and the amount of thrombus. There were also significant differences in renal infarctions caused by different types of catheters.

Animals↗
PubMed1979

Effects of heparin, aspirin and dipyridamole on thrombus formation on venous catheters.

Heparin, aspirin and dipyridamole were given alone or in combination to groups of sheep which had polyethylene catheters inserted into facial and saphenous veins. Animals were killed after 3 or 9 days. Neither aspirin nor dipyridamole reduced the amounts of thrombus on the catheters at autopsy. Heparin reduced thrombus only when sufficient was given to reduce blood coagulation.

Animals↗
PubMed1976

Thrombus formation on indwelling venous cannulae in sheep : effects of time, size and materials.

Three experiments were performed to measure thrombus formation on plastic cannulae inserted by cut-down into veins of sheep. On polyethylene tubing, considerable thrombus was present after one day and the amount increased in the subsequent 13 days. When different sized polyethylene tubings were tested, thrombus tended to form in relation to the surface area. Smaller tubings had smaller proportions of their lengths covered with thrombus. There were differences between types of plastics with one batch of polyvinylchloride tubing being virtually non-thrombogenic.

Animals↗
PubMed1976

Measurement of thrombus formation on intravascular catheters.

Relative thrombogenicities of several brands of intravascular catheters were measured in the saphenous and cephalic veins of sheep. Differences in thrombogenicity between brands of up to eleven fold were found. At least one brand contained an ingredient which was locally toxic to sheep and which caused phlebitis in cannulated vessels. The brands tested were made from six types of plastics. It is suggested that differences in manufacturing technique may be more important than the type of plastic in determining the thrombogenicity of catheters.

Animals↗
PubMed1975

Rates of passage of digesta and water absorption along the larg intestines of sheep, cows and pigs.

In 5 cows, the mean length of the large intestine was only slightly greater than that of 21 sheep and 3 pigs. At about one-fifth of the way along the large intestine of the sheep and cows, corresponding to the end of the proximal colon and start of the spiral colon, there were marked reductions in the amount of digesta present and in the lumen diameter. In pigs these parameters decreased gradually along the large intestine. In all parts of the large intestine, the cows had more water in the digesta than did the sheep or the pigs. Nevertheless, the decrease in water content between the caecum and the rectum was similar for the cows and the sheep but less in the pigs. The rate of passage of digesta increased gradually along the large intestine of the pigs, but in the cows and sheep the rate was least in the caecum and proximal colon and greatest in the spiral colon. The total retention time for digesta in the large intestine was approximately 30, 20, and 9 h in the pigs, sheep, and cows respectively. The rate of water absorption from the large intestine was most rapid in the cows and slowest in the pigs. Differences in faecal water content between the species were not due to differences in retention times in the large intestine.

Animals↗